Major Depressive Disorder

Newer therapies, such as ketamine or esketamine, or the broader use of bright light therapy, made an updated clinical practice guideline for treating major depressive disorder (MDD), but psilocybin and cannabis did not.

Nearly 30% of youths are affected with worsening mental health by the end of adolescence, with anxiety typically presenting in childhood and depression during the teenage years, but the problem is even more acute for Black and Latinx youth.

Three types of salient beliefs were investigated in this study that examined why mothers would or would not participate in depression screening via genetic salivary testing, with the results indicating potential for mental health disparities among diverse populations.

Feeling depressed, anxious, worried, stressed, or lonely was linked with a higher risk of developing long COVID and hurting the ability to function in daily life, according to a study published this week.

Groups at risk for underrecognition and undertreatment of depression had improved rates of depression screening after implementing routine adult depressions screening in primary care.

A study conducted in the Netherlands found older adults with depression were at greater risk of polypharmacy than those without depression.

This new study of data from Kaiser Permanente Southern California compared outcomes for behavioral health referrals among patients with breast cancer between those receiving a tailored intervention or an education-only approach.

The analysis identified 4 genes that were driven by atopic dermatitis (AD) and which had significant expression changes in favor of MDD development.

A causal relationship between major depressive disorder (MDD) and multiple sclerosis (MS), and vice versa, was not found in a recent Mendelian randomization study, while higher body mass index (BMI) was shown to increase the risk for both.