Migraine

Researchers assessed 3 risk factors for migraine in children and adolescents: stress, sleep poverty, and alimentation.

Among children and adolescents suffering from migraine, results from a prospective study show being overweight is associated with a higher frequency of migraine attacks and separation anxiety symptoms.

If green light therapy were proven to be effective for migraine, it would be hugely important, said Frank Porreca, PhD, professor of pharmacology and anesthesiology at the University of Arizona and a member of the Department of Collaborative Research at Mayo Clinic in Arizona.

While migraine was more manifest in some patients during the pandemic, others were able to adopt healthier habits, said Peter McAllister, MD, a neurologist, board certified headache specialist, and medical director of the New England Institute for Neurology and Headache.

The genetic determinants of sleep and migraine partly overlap, suggesting sleep disturbances may causally influence migraine etiology and could be targets for migraine treatment, according to results of a Mendelian randomization study.

If you only experience migraine with your period for a few days, it would be difficult to recommend taking a drug all the time, said Stephen Silberstein, MD, professor of neurology at Thomas Jefferson University and director of the Headache Center at Jefferson Health.

Patients with chronic migraine who received a combination therapy of erenumab and onabotulinumtoxinA exhibited significant reductions in monthly headache days and monthly migraine days.

The CGRP story is really based on reverse translation and other observations in humans will be pursued along that same model, said Frank Porreca, PhD, professor of pharmacology and anesthesiology at the University of Arizona and a member of the Department of Collaborative Research at Mayo Clinic in Arizona.

Variability in prevalence of vestibular migraine, depending on ethnicity and geographic location suggests, a combined genetic and environmental contribution to VM, according to results of a systematic review.

There can be a myriad of reasons for the patterns observed in our study on alteration of migraine frequency and triggers during the pandemic, said Faraidoon Haghdoost, MD, a general practitioner and PhD student at The George Institute for Global Health in Sydney, Australia.

In a study published in Scientific Reports, researchers highlighted structural and functional brain differences among those who suffer menstrual-related migraine (MRM) and pure menstrual migraine (PMM).

Increased time spent in front of computer screens, less time spent sleeping, and less access to gyms have led my patients to have a lot more migraines, said Peter McAllister, MD, a neurologist, board certified headache specialist, and medical director of the New England Institute for Neurology and Headache.

Data from a 5-year open-label treatment period on the safety profile of erenumab (Aimovig) showed the treatment helped patients with episodic migraine achieve a sustained reduction in the number of monthly migraine days and the number of days in which therapies were needed for acute migraines.

Migraine is a significant risk factor for postoperative nausea and vomiting, according to results of a retrospective study published in the Journal of Clinical Medicine.

Medication overuse headache is a huge problem in societies that don't have access to proper headache care as patients take more over-the-counter, readily available treatments, said Rigmor Jensen, MD, professor of neurology at The University of Copenhagen and director of the Danish Headache Center.

In an attempt to develop a multivariable predictive model for days with new-onset migraine headaches, researchers found episodic migraine attacks were not predictable based on self-prediction or on self-reported exposure to common trigger factors.

Treatment guidelines for comorbid depression and migraine are warranted to ensure optimal efficacy and avoid possible pitfalls in psychopharmacotherapy, according to study results.

According to a study published in Headache, greater occipital nerve blocks (GONB) with bupivacaine were not as effective as intravenous (IV) metoclopramide as a first-line treatment for migraineurs who presented to emergency departments.

New research published in JAMA Neurology highlights disparities in migraine based on sexual orientation in the United States.

Many women suffering from migraine say the condition affects family planning, while this finding is more prevalent among women who are younger and experience menstrual and chronic migraine.

Prevalence of restless legs syndrome is elevated among individuals with migraine according to a systematic review and meta-analysis published in Pain Research and Management.

In individuals suffering from chronic and episodic migraine, a preliminary study shows exposure to green light therapy significantly reduced headache days and improved both intensity and duration of headache attacks.

A systematic review concluded that a correlation between magnesium deficiency and headaches exists, while magnesium deficiency may be an independent risk factor for migraine.

Compared with patients with epilepsy, migraineurs tend to suffer more from psychological difficulties, according to a study published in Journal of Multidisciplinary Healthcare.

A study using real-world data from an Italian region found two-thirds of patients with chronic migraine treated with erenumab transitioned to episodic migraine within 6 months.