Rheumatology

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When patients with rheumatoid arthritis experience failure of an anti–tumor necrosis factor (anti-TNF) therapy, clinical guidelines support either cycling to a different anti-TNF agent or switching to a treatment with a different method of action (MOA). However, payers often require cycling of anti-TNF options before they will reimburse for treatments with a different MOA.

In a new study, published in Arthritis Research & Therapy, a research team led by Soo-Kyung Cho, MD, sought to investigate the incidence of malignancy in early rheumatoid arthritis and found that the use of biologic disease-modifying anti-rheumatic drugs decreased the overall risk of developing malignancies, though it did not affect the risk of developing hematologic malignancies.

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