Evidence-Based Oncology October 2019
Evidence-Based Oncology October 2019
Donna Cryer, JD
Alexander J. Alvarnas; and Joseph C. Alvarnas, MD
An Interview With Debra Patt, MD, MPH, MBA, by Jaime Rosenberg
Real-World Evidence: Research Reveals a Lack of Racial Diversity in Clinical Trials for Cancer Drugs
ASTRO Calls for Voluntary Start, Scaling Back Excessive Cuts in CMS' Proposed Radiation Oncology Model
Paul Harari, MD, FASTRO
Matthew Gavidia and Jaime Rosenberg
AJMCtv October 2019
Produced by Jaime Rosenberg
Joseph Alvarnas, MD
AJMCtv October 2019
Produced by Jaime Rosenberg
AJMC®TV interviews let you catch up on what’s new and important about changes in healthcare, with insights from key decision makers—from the clinician, to the health plan leader, to the regulator.
Richard Snyder, MD, Executive Vice President, Facilitated Health Networks; Chief Medical Officer, Independence Blue CrossWith more novel, costly therapies being approved and patients being responsible for more costs, how do you think this will impact the prevalence and popularity of value-based agreements?
I think it will absolutely increase the speed to value-based care and also the kinds of arrangements that we will see going forward. There are quite a few creative ideas emerging. Amongst them, the Blue Cross Blue Shield Association has a number of direct contracting models to eliminate the need for a provider to invest in the cost of a medication, [which will] thereby gain perhaps somewhat of a discount and facilitate the patient care delivery without incurring as much out-of-pocket costs for the patient.
How do value-based agreements benefit all stakeholders, including providers, patients, and payers?
If they’re done correctly, a value-based contract should benefit all 3. So, I’ll give you a few examples. First of all, from a patient perspective, we can define the benefits to reward patients with lower out-of-pocket costs if they go to a Blue Distinction Center or a center of excellence to get their care, and by steering them to such a location, they’re virtually guaranteed to have better clinical outcomes at a lower cost. That is the basis for the Blue Distinction Centers program that the Blue Cross Blue Shield Association has been promulgating in and around things like [chimeric antigen receptor] CAR T-cell therapy and Luxterna and other expensive drugs.
Typically, they reward the payer with lower total cost of care, and oftentimes a warranty in the event the medication does not effectively control the diagnosis. Obviously, that is a good thing since a large proportion of the care today is being paid for by employer groups through self-funded arrangements, and these very, very costly drugs that are emerging from the pipeline put a significant stress on their [profit and loss statements], so from a payer perspective and ultimately our customers, the employer group, it helps to control costs and ensure quality outcomes and reward us with a warranty in the event the outcome is not optimal. In the case of the provider, a lot of these arrangements do not require the provider to pay out the cost of stocking or storing these medications until a patient is waiting for them. With some of these programs, precertification barriers or limits can be reduced, since they’re very unusual circumstances—rare diseases where the medication otherwise wouldn’t be used. So, I think there are plenty of reasons why the member—the patient, the payer—the ultimate customer the employer group or the government, and ultimately the provider delivering the service can benefit from value-based contracts.
How important are population health management and coordination of care in value-based contracting?
They’re actually integral to value-based contracting. When we do episode of care payments, we are paying for a period of time and everything that happens in that period of time, so it’s critically important that the right patients are chosen for that episode, that there’s extremely good coordination to prevent leakage out of the system of care to other systems, and ultimately that patients adhere to any medication regimens that they’re prescribed and that post-acute care when the patient goes home for a period of time, that’s included in the episode, is well managed so they don’t bounce back to an emergency room or a hospital or end up having a complication that could have been otherwise avoided if we had been monitoring them more closely.
In today’s world, we have technology, whether it’s video capabilities or Bluetooth-enabled monitoring devices to determine whether patients are adhering to their treatment plans and whether they’re having any early signs of a complication that could result in a readmission to the hospital or emergency room or avoidable testing and treatment.
What are your thoughts on the proposed Radiation Oncology Model and the fact that CMS wants it to be mandatory?
Stephen Schleicher, MD, MBA, Medical Oncologist, Tennessee Oncology
The big hype right now is this proposed radiation oncology bundled payment. This would be the first true bundled payment to come in oncology. The [Oncology Care Model] OCM is an episode-based payment, but it is not a bundle, and then the other experiments like Medicare’s [Bundled Payments for Care Improvement], the comprehensive joint replacement model—both had nothing to do with oncology. So far in oncology, outside of [Merit-based Incentive Payment System], the OCM was voluntary, so this is a big change in oncology to have a mandatory payment model, and as we’ve seen in OCM, there are unpredictable consequences of the methodology, such as the novel therapy drugs coming out after the baseline.
So, in my opinion, I’d prefer a voluntary model where groups that are excited about being on the cutting edge can be a part of that and help us learn where the challenges are in bringing a bundle to radiation oncology and then perhaps make it mandatory in the future, based off the initial feedback.
How does the implementation of high-cost, novel drugs into clinical practice after the baseline period cost calculations further add to the challenge of lowering costs under OCM?
This remains a challenge since the baseline period was up until 2015 and we had this, really, immunotherapy boom happen after that. So, it is a challenge and Medicare does a great job trying to predict what costs should be based off these new novel therapies, but we have some data that was presented at [the 2019 American Society of Clinical Oncology annual meeting] ASCO and is going to be published shortly showing that this is still not a perfect methodology to account for these, so I think understanding those challenges and trying to understand the risk that those challenges have on us going forward is important. I will say performance period 4, which included the first half of 2018, was when immunotherapy came to the front line of non-small cell lung cancer, so it was kind of a test case for the model, and I think I was pleasantly surprised that the prediction had been better than expected when we got our performance period 4 results.
Nina Chavez, MBA, FACMPE, Chief Operating Officer, New Mexico Oncology Hematology Consultants, LtdNow that we are a few years into the OCM and other value-based models, have community oncologists become better at practicing the business of oncology?
It’s a difficult question in the sense that community oncology [aren’t] businessmen. Doctors don’t go to medical school to get a business degree, and, unfortunately, in our healthcare environment, if you’re going to be an independent practice, you have to understand the business of medicine that you’re in. I think that the OCM over the past couple of years has helped us look at things that we didn’t really think of from an oncology perspective.
You’re always looking at the patient first, you’re always looking at that patient outcome, but now we have to look at the total cost of care, we have to look at that patient engagement piece—not just saying that we did it but also documenting it and having those documented interactions, which is something more for the payers than, really, the patient.
So, I do think that oncologists have become better businesspeople.…They’ve had to in order to survive in this environment and be able to take care of their patients in a better way.
With therapies like CAR T-cell therapy entering the market, will reimbursement present significant challenges to providers?
CAR T…I was talking to my doctor about this because I’m not clinical, and I want to make sure I got her opinion, and she said that with CAR T, the insurers are not paying for it right now; we don’t know what’s going to happen. It really should be happening in a hospital, but if you’re not partnering with your hospital and you’re trying to do it in an independent practice, it’s not going to be easy.
I think from a cost perspective, we don’t know what the market’s going to do; we don’t know what the payers are going to do. We do know that we can’t get that medication—we can’t get CAR T therapies very easily in community oncology. We can’t even get it from the [group purchasing organization] we currently have.
You have to go through a certain specialty, and it is very costly, so I think that remains to be seen. It’s something that we’ll have to kind of see how it goes.
Lee Schwartzberg, MD, FACP, Executive Director, West Cancer Center; Chief Medical Officer, OneOncologyThe US Preventive Services Task Force (USPSTF) recently updated its recommendations for BRCA1/2 screening and testing and included women with a history of several cancers and women with ancestry associated with the mutations. What are your thoughts on this?
Who should be screened for genetic testing for cancers is an ever-evolving issue, and we recently saw the USPSTF come out with a new recommendation. To me, this was very interesting, because they tend to be a very conservative group, and they actually got ahead of some of the other guideline committees by mentioning that all women who have a personal history of breast, ovarian, or other cancers should be tested. So, we’re starting to see this movement toward universal testing. We’re not quite there yet, but this is a broadening of who should be tested.
Testing for germline mutations for hereditary cancers is getting cheaper all the time. It’s getting easier to talk about, although we still need our genetic counselors, and we need a workflow that works with this because genetic testing doesn’t just affect our patient, it affects the whole family. So, it’s a little different concept from the way we take care of patients. I think there’s more and more comfort with disseminating this information, so I strongly endorse that recommendation. Not every payer has agreed to that yet, but it’s definitely moving in that direction.
The reason this is important is that up to 5% to 10% of women who have cancer, one of the female cancers, will have a mutation, and that’s a pretty substantial number when you’re dealing with a quarter of a million breast cancer diagnoses per year. So, this old sort of arbitrary “do triple-negative breast cancer if they’re under 60”—there’s a lot of arbitrariness in who we’re defining should be tested. The broader we make it, the better it is.
What are your thoughts on USPSTF leaving men out of its updated recommendation for BRCA1/2 screening and testing?