Latest Conference Articles

A symposium on the new drug class, SGLT2 inhibitors, drew plenty of interest from attendees at the American Diabetes Association meeting in San Francisco. SGLT2 inhibitors have gained notice, both for their ability to reduce A1C levels and for their potential to help patients lose weight.

A symposium that focused on the relationship between behavioral health and diabetes examined how the challenges of living with the disease wear on patients over time, ahead of results presented Sunday showing that much of what is diagnosed as "depression" in diabetes may not be. Presenters offered 3 models for better coordination of care.

A diabetes patient navigator program in Birmingham, Alabama, a joint project of the American Academy of Family Physicians Foundation and Sanofi US, resulted in lower A1C levels for its participants. Patients also reported higher levels of satisfaction in managing their disease.

For years, the standard for treating type 2 diabetes mellitus (T2DM) has been step therapy. Patients are told to make changes in their diets and to exercise more. Then, most start metformin; if T2DM progresses, doctors add drugs from among the dozen other classes, either alone but typically in combination.

Some experts argue that overdiagnosis (OD) and overtreatment (OT) of cancer is common and increasingly costly. Others argue that current cure rates are high because of the screening processes currently in place. Both viewpoints were debated during the session "Overdiagnosis and Overtreatment in Cancer: Point/Counterpoint."

The health services research poster session held in the afternoon on the penultimate day of the 50th annual meeting of the American Society of Clinical Oncology (ASCO) presented different perspectives on issues that determine patient care decisions. This is an important discussion, especially in light of the recent report by The Wall Street Journal on WellPoint's effort to promote oncologist adherence to standardized treatment guidelines.

The discussion on value in cancer care was rekindled today at the 50th annual meeting of the American Society of Clinical Oncology, but this time on a global scale. The session, "ASCO/European CanCer Organisation (ECCO) Joint Session: Value and Cancer Care," saw participation from physicians and economists from around the world, with individual perspectives on defining value and the programs being developed to address the issue.

Velcade (bortezomib), developed by Millenium Pharmaceuticals, is a proteasome inhibitor that is currently approved for the treatment of multiple myeloma and relapsed mantle cell lymphoma. Several abstracts were presented at the annual meeting of the American Society of Clinical Oncology this year for its use in other indications.

The second day at the 50th annual meeting of the American Society of Clinical Oncology ended with a session entitled "Health Care in America in 2014: Current and Future Implications of the Patient Protection and Affordable Care Act" (PPACA). The presenters provided an overview of the recent and anticipated changes related to the PPACA as well as its timeline.

"The Value of Cancer Care and the Professional and Ethical Obligations of the Practicing Oncologist: A Debate" delved into the ethical issues raised by the economic reality of the rising costs of cancer care for the practicing oncologist.

ABT-199, the result of a collaboration between AbbVie and Genentech, is a selective, potent, orally available BCL-2 inhibitor. The drug is being developed in collaboration by the two companies for acute myelogenous leukemia and chronic lymphocytic leukemia (CLL).

While the incidence of cancer continues to grow, novel and targeted therapies being developed have seen much improved survival for even the deadliest of cancers. New innovations in cancer diagnosis and treatment are associated with high cost. Cancer therapy constitutes nearly 11% of the total healthcare budget, and it is rapidly growing.

On the second day of the 50th annual meeting of the American Society of Clinical Oncology (ASCO), a session titled, "Targeting EGFR: the next 10 years" provided a progress report on the successful targeting of the protein in non-small cell lung cancer (NSCLC).

Attendees at the 167th Annual Meeting of the American Psychiatric Association (APA), convening at the Jacob K. Javits Center in New York City, appreciated Sunday's opportunity to hash out practical day-to-day issues at Meet the Author: Evidence-Based Guide to Antidepressant Medications and Antipsychotic Medications, with editor Anthony J. Rothschild, MD, director of the Center for Psychopharmacologic Research and Treatment, at University of Massachusetts Medical School.

The theory behind integrated care models in mental health is easy to grasp: Those who have depression or anxiety often have other problems, such as high blood pressure or unexplained pain, so having a psychiatrist collaborate with a primary care physician (PCP) makes sense.

In 2010, the topic of integrated care in mental health was still at the edges of practice, so much so that the topic only merited a single workshop at the meeting of the American Psychiatric Association (APA) in New Orleans.

Patrick J. Kennedy, former US Representative for Rhode Island's 1st Congressional District, says that he authored the Mental Health Parity & Addictions Equity Act in 2008, which was then incorporated into the Affordable Care Act in 2010. The parity law went into effect in January 2014, and by 2015, more health plans are expected to be covered under it.

Thomas R. Insel, MD, the director of the National Institute of Mental Health (NIMH), started his talk with a grim picture of the nation's mental health: a January 2013 report from the Institute of Medicine found that mortality rates for US men and women under 50 years ranked last and near last, respectively, among 18 developed countries, with causes including car accidents, gun violence, and drug overdoses.

Healthcare is an industry in massive transition, and Kimberly White, MBA, Numeroff and Associates, based in St Louis, Missouri, is working front and center on helping administrators and physicians to change their business models to promote survival in an unforgiving business market.

On the final day of the National Association of Managed Care Physicians' Spring Managed Care Forum 2014 in Orlando, Jeffrey Curtis, MD, director, Arthritis Clinical Intervention Program at the University of Alabama, Birmingham, gave a clinical presentation of studies that focused on using multiple biomarkers to assess treatments of rheumatoid arthritis.

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