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Wound care is costly, costing at least $28.1 billion annually for the Medicare population alone. Treating patients with wounds can be complex as they often have multiple comorbidities that impede wound healing.

The results showed that in half of patients with cancers of unknown origin, next-generation sequencing located the primary site of origin and, in those who were matched to a therapy, half achieved a clinical benefit.

Improved understanding of the early mechanisms of chronic kidney disease (CKD) may be the next step in efforts to delay or reverse disease progression.

Researchers discuss the current state of digital health for the treatment of Parkinson disease, particularly patient perspectives and specific technological innovations being investigated.

According to the researchers, few treatments have been able to reduce the thrombotic burden in patients with polycythemia vera (PV) and essential thrombocytopenia (ET), and progress on this front has been hindered by a lack of studies designed to assess a treatment’s impact on thrombotic events.

Patients with chronic obstructive pulmonary disease (COPD) with clinically important deterioration were found to have greater exacerbations and mortality risks; however, triplet therapy could help rectify that.

Deep learning algorithms to diagnose skin disease like atopic dermatitis could save time for providers while increasing accuracy, according to a pilot study.

Reduced left ventricular ejection fraction, longitudinal strain, and circumferential strain have possibly been linked to development of heart failure among elderly individuals.

A survey released this month of US patients with blood cancers shows a somewhat surprising level of hesitancy about receiving a COVID-19 vaccine, but because patients with cancer were not included in clinical trials, the situation for this population is somewhat nuanced.

Spinal muscular atrophy treatment Zolgensma was found to be safe and effective for long-term use and use in presymptomatic patients, according to posters presented at the 2021 MDA Virtual Clinical & Scientific Conference.

The researchers of the study say their findings may aid the hematological community in determining the value of integrating gene expression profiles in contemporary prognostic models to better identify high-risk patients with a poor prognosis.

Among these factors, having a higher degree of disability from multiple sclerosis (MS) was independently associated with higher morbidity and mortality risks from having a comorbid case of COVID-19.

European Medicines Agency announces AstraZeneca vaccine is safe; a low-dose aspirin regimen may help reduce severe COVID-19 outcomes; President Joe Biden sends excess AstraZeneca vaccines to Canada and Mexico.

Coverage of our peer-reviewed research and news reporting in the health care and mainstream press.

This week, the top managed care news included AstraZeneca refuting blood clot links to COVID-19 vaccine; 2021 V-BID Summit celebrates 20 years of policy achievements for value-based insurance design; Managed Care Cast discusses 4 strategies payers can use to ensure opioid use disorder care.

To mark World Sleep Day, a survey issued this week spotlights trends that have impacted sleep quality in the past year, including rising stress amid the COVID-19 pandemic and the prevalence of unattended snoring that may signal an underlying health condition.

Minimal residual disease (MRD) is being used more frequently in clinical trials and to identify the best treatment course for patients, but unknowns remain about the optimal use of MRD testing.

Despite HHS’ recommendation that everyone with HIV start antiretroviral therapy (ART) soon after their diagnosis, uptick disparities remain and are especially apparent among persons with drug abuse or dependence.

Xavier Becerra, California's attorney general, will become the next secretary of HHS after the Senate voted 50-49, split by party lines.

The study examined the cost to Medicare when patients with end-stage renal disease switched from their employer-based health insurance to Medicare between 2007 and 2017 before the end of the 30-month coordination period.

A new study suggests that 3-feet social distancing is sufficient for in-person instruction in public schools; Amazon announces it will offer its Amazon Care telemedicine program to private employers nationwide; ACIST Kodama Intravascular Ultrasound Catheter recalled.

Patients with pulmonary arterial hypertension (PAH) and chronic thromboembolic pulmonary hypertension had similar incidence of COVID-19, but the impact on clinical operations at the centers that treat these patients was substantial.

Patients with multiple sclerosis have high rates of urinary and kidney infections, inpatient hospitalizations, and outpatient hospital claims, according to recent results presented at the Americas Committee for Treatment and Research in Multiple Sclerosis annual meeting.

Patients with obstructive sleep apnea (OSA) and history of cardiovascular disease treated with continuous positive airway pressure (CPAP) therapy were shown to report 20% higher levels of moderate physical activity compared with non-CPAP users, with these patients also more likely to exercise at levels meeting clinical recommendations.

A panel of experts provided consumer insights into value-based insurance design (VBID) and how the COVID-19 pandemic may have changed consumer behaviors in a way that VBID may be able to address as the country emerges from the pandemic.

Responses from a study of in-person focus groups show that not only do patients report adverse effects on quality of life, physical well-being, and mental health but that their caregivers do as well.

While an association was found between dementia and the most common form of lupus, links to other autoimmune diseases—rheumatic arthritis, Sjögren’s syndrome, and Behcet’s disease—were not found.

Results of a scoping review of 19 studies indicate estrogen likely plays a key role in migraine pathogenesis but affects patients in different ways depending on past medical history, age, and use of hormonal therapy.