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A look into the US cities hardest hit by cases of coronavirus disease 2019 (COVID-19); Anthony Fauci, MD, urges Americans to double down on health precautions amid COVID-19 surges; a study spotlights risk of high health care costs among the insured.

This week, the top managed care news included the Supreme Court signaling willingness to uphold the Affordable Care Act; Pfizer’s coronavirus disease 2019 vaccine shows 90% efficacy; racial disparities in lung cancer screenings and prescribing biologics.

Age, sex, and body mass index typically drive the development of obstructive sleep apnea, noted Krishna M. Sundar, MD, clinical professor, Pulmonary Division, Department of Medicine, medical director, Sleep-Wake Center, University of Utah.

Chimeric antigen receptor (CAR) T cells can be highly effective, but the durability of the therapy has been lacking in many patients with hematological malignancies. Many efforts are underway to fix this problem.

The FIDELIO-DKD program is perhaps just the beginning of seeing how finerenone can be used, said Rajiv Agarwal, MD, MS, FASN, a professor of medicine at Indiana University School of Medicine and a staff physician at the Veterans Affairs Medical Center in Indianapolis, Indiana.

Living in a neighborhood rife with violent crime and prostitution was linked in this recent study to worse virologic control among pregnant woman living with HIV.

A report by PwC discusses the health care agenda of President-elect Joe Biden, particularly how his term will shape the future of the Affordable Care Act, value-based care, and drug prices.

Researchers have identified additional mutations in both SMN1 and other genes, some of which may be associated with the onset of spinal muscular atrophy (SMA).

The Gates Foundation will add another $70 million of funding for vaccines and treatments against coronavirus disease 2019 (COVID-19); nursing homes see rising COVID-19 cases; finding health coverage for workers laid off due to the pandemic.

Michael S. Fitts, assistant dean for user access and diversity at the University of Alabama at Birmingham, discusses misconceptions of Parkinson disease related to race and age, as well as advice for patients in their treatment journey.

Experts spotlighted sex- and gender-specific changes in normal sleep and sleep disturbance, as well as attributable risk factors, during a session at the CHEST 2020 annual meeting.

Intravenous diuretic treatment of patients with decompensated heart failure can increase urine output, promote weight loss, and improve dyspnea.

Between 2003 and 2016, the United States saw a 4-fold increase in drug use–related endogenous endophthalmitis hospitalizations, contributing to a substantial health care use burden.

The US may have inadequate testing for coronavirus disease 2019 (COVID-19); potentially 80% of new COVID-19 cases are linked to indoor venues; protection against measles and mumps is suboptimal among cancer patients.

Treatment targets include several interleukins, immunoglobulin E, and alarmins, pointed out Nicola Hanania, MD, MS, pulmonary critical care physician and director, Airway Clinical Research Center, Baylor College of Medicine, Houston.

If you only experience migraine with your period for a few days, it would be difficult to recommend taking a drug all the time, said Stephen Silberstein, MD, professor of neurology at Thomas Jefferson University and director of the Headache Center at Jefferson Health.

In what is believed to be the first study of its kind, investigators found patients with leukemia face a higher risk of suicide than the general public, especially if they had acute myeloid leukemia.

Improvements in completed visits while using telemedicine to conduct rheumatology visits during the coronavirus disease 2019 pandemic may present an option for continued telemedicine use for follow-up care.

In a pair of sessions at the Quality Cancer Care Alliance Virtual Fall Leadership Summit, speakers discussed the promise of precision medicine for not only informing individuals’ cancer treatment decisions but also identifying individuals at high risk before disease develops.

Patients with newly diagnosed multiple myeloma often receive twice-weekly triplet regimens of carfilzomib, lenalidomide, and dexamethasone (KRd). New data suggest less frequent dosing can be equally successful.

Black individuals with diabetic macular edema (DME) exhibited a significantly lower likelihood of visual acuity improvement following intravitreal bevacizumab treatment compared with White and Hispanic patients.

Efficiency, collaboration, and efficacy are key drivers in creating clinical pathway buy-in, with updates also vital to incorporate the latest trends and insights in cancer care.

A recent study of female breast cancer survivors shows that feelings toward body image were consistently worse among those who had a bilateral mastectomy vs breast-conserving surgery.

During oral arguments, the justices asked skeptical questions regarding Republican state efforts to get the Affordable Care Act (ACA) overturned.

FDA approves a coronavirus disease 2019 (COVID-19) antibody treatment; North Dakota braces hospitals for surging cases; fruit consumption among children is low.

What is feasible for one person may be unaffordable for another, said Milena Murray, PharmD, MSc, BCIDP, AAHIVP, associate professor, Midwestern University Chicago College of Pharmacy, who practices at the Northwestern Medicine Infectious Disease Center.

David Weisenfeld, JD, legal editor at XpertHR, previews how employment law rulings may be affected by the Senate's recent confirmation of Justice Amy Coney Barrett to the Supreme Court.

New data to be presented at the American Academy of Ophthalmology’s Annual Meeting highlight the efficacy of Tepezza (teprotumumab), the first and only FDA approved medicine for thyroid eye disease.