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The family that owns the drug company at the center of the nation’s opioid problem reached a tentative settlement with thousands of municipal governments and nearly 2 dozen states that sued the pharma industry for its role in creating the crisis; nearly 8 in 10 Americans back legislation to protect people from surprise medical bills; the water crisis in Flint, Michigan, was not only about lead in the water—it was also about a deadly outbreak of Legionnaires’ disease.

The study researchers, who examined 1600 premenopausal women who underwent bilateral oophorectomy between 1988 and 2007, found that psychiatric symptoms may lead a woman to undergo an oophorectomy, even after receiving a nonmalignant diagnosis.

Predetermined topics to be discussed by the 2020 dietary guidelines committee failed to mention risks correlated to red meat, processed foods, and appropriate sodium intake, which contribute to the impending epidemic of lifestyle diseases.

In a new study, researchers compared the associations between several measures of breathing patterns during sleep and daytime sleepiness related to obstructive sleep apnea (OSA). They found that nighttime oxygen desaturation severity was a strong predictor of sleepiness.

The Trump administration said Wednesday that the FDA will “prioritize” enforcement of flavored e-cigarette regulations in an effort to get them removed from the market.

The discussion about whether existing inflammatory bowel disease (IBD) or new IBD can worsen after secukinumab therapy is not resolved, the researchers said.

Nearly 28.5 million Americans are uninsured or underinsured, leaving them at risk for medical costs they may not be able to afford. Surprise billing is particularly problematic for acute, or emergency cases.

Cumulative viral load was associated with increased risk of kidney disease, suggesting that early viral suppression could decrease incidence of disease.

Health insurers will shell out $743 million in rebates to consumers under an Affordable Care Act (ACA) rule; the human papilloma virus (HPV) vaccine offers benefits to men who are not vaccinated; Apple is launching 3 studies to assess the Apple Watch’s ability to monitor health and medical conditions.

All patients with metastatic breast cancer should undergo genetic testing based on the prevalence of P/LP variants in patients with metastatic breast cancer, which can have therapeutic implications.

According to a report from the US Census Bureau, the rising rate of the uninsured appears to be a result of a slump in Medicaid coverage. Health policy experts say the decline reflects efforts by the Trump administration to undermine the Affordable Care Act.

A new liquid biopsy test could detect microsatellite instability and tumor mutational burden, which can distinguish which patients are likely to respond to immune checkpoint inhibitors.

Juul is being investigated for making unauthorized safety claims, while the governor of New York proposes to ban flavored e-cigarettes; Sutter Health is being sued for its role in rising healthcare costs; a European doctor who uses telemedicine and internet prescribing to provide American women with mifepristone and misoprostol to induce abortion in the first trimester is suing the FDA.

In 2 studies published in The Lancet Neurology, ozanimod was well tolerated and had a lower relapse rate in patients with relapsing multiple sclerosis.

The meta-analysis showed that more than 1,125,000 men around the world have the inherited bleeding disorder; 418,000 of those have a severe version of the mostly undiagnosed disease. Previously, only 400,000 people globally were estimated to have hemophilia.

The agency has approved nintedanib (Ofev) to slow the rate of pulmonary function decline in adult patients with interstitial lung disease associated with systemic sclerosis or scleroderma.

School-based telemedicine was shown to potentially enhance healthcare benefits for children with chronic diseases, such as asthma, in rural and medically underserved communities, according to a study.

Human leukocyte antigen c (HLA‐C), a protein encoded by the HLA-C gene, plays an important role in protecting against both cancer and viruses. At the same time, it has been implicated in autoimmune diseases, including rheumatic diseases, though the mechanism by which it contributes to the pathogenesis of these diseases is not yet clear.

Oxycontin manufacturer rejects settlement for role in opioid epidemic and moves toward bankruptcy; new vaping-related respiratory illnesses reported; Senator Kamala Harris, D-California, a 2020 presidential candidate, proposes a new healthcare plan for veterans.

Employers are recognizing the need to modernize the employee health experience following research that demonstrates the disconnect between companies’ investment in health benefits and the impact on employee health.

The Harvard researchers designed this new device with consideration of the human pancreas, where islets—also known as islands of cells—receive glucose level information from the bloodstream, then adjust their insulin production.

A total of 45% of patients made at least 1 error when using an inhaler, and the number of errors per patient ranged from 1 to 6.

Cloud faxing can provide the opportunity for providers to be more productive and lower costs.

A study investigating the effects of weather and air pollution on migraine found that higher relative humidity was associated with higher odds of migraines during warmer seasons. Traffic-related pollutants was linked with migraines in colder weather.

Using vorinostat with pembrolizumab can help improve the efficacy of the immunotherapy in non–small cell lung cancer.

The proportion of people living with HIV with more than 90% adherence to antiretroviral therapy (ART) increased from 33.5% in 2001 to 52.4% in 2010.

Men without chronic obstructive pulmonary disease (COPD) showed an associated difference in bone quality based on their smoking status and pack-years, according to a new study.

A recent study explored the efficacy of brentuximab vedotin (BV) in patients with high-CD30–expressing non-Hodgkin lymphoma (NHL) to determine who is most likely to benefit.