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Depression has been associated with poorer outcomes for patients who have acute coronary syndrome (ACS), including myocardial infarction. Now, new research indicates that treating depression may improve long-term cardiac outcomes for patients with ACS.

KEYNOTE-048, a phase 3 trial studying pembrolizumab (Keytruda) as a first-line treatment for patients with recurrent or metastatic head and neck squamous cell carcinoma (HNSCC) whose tumors overexpress PD-L1, has met a primary end point of overall survival.

A recent study investigated the associations of migraine with pain symptoms among outpatients with major depressive disorder during a 10-year period, finding that migraine treatment should be integrated into treatment for depression to improve patients’ pain symptoms and health-related quality of life.

The Trump administration said it will restart the risk adjustment payment program just weeks after suspending the payments; the first pill in a decade has been approved to treat pain caused by endometriosis; Eli Lilly executives said during the second quarter earnings call that the idea of importing drugs from abroad was “the wrong road to go down.”

When a patient experiences an adrenal crisis associated with Addison disease (primary adrenal failure), hydrocortisone and fluid resuscitation must be given immediately in order to prevent hypotensive shock and death. A recent clinical audit evaluated healthcare professionals’ management of adrenal crisis, and found that there is a clinical need to improve the acute management of this life-threatening condition.

A second biosimilar to Amgen’s Neupogen, which treats neutropenia, has been approved in the United States. The FDA approved Pfizer’s filgrastim-aafi, which will be sold under the brand name Nivestym. Zarxio (filgrastim-sndz) was the first filgrastim biosimilar approved by the FDA in 2015.

Despite pre-exposure prophylaxis (PrEP) being crucial for preventing new HIV infections and working toward an end to the epidemic, the treatment is still out of reach for many.

A study of over 35,000 women with early-stage breast cancer found that where you live makes a difference in terms of what kind of posttreatment imaging is received, due to geographic variation.

Researchers recently aimed to develop a predictive model to identify patients at risk of developing severe COPD exacerbations, finding that for every 2 patients identified to be at risk of severe flare-up of disease, 1 patient may experience a severe exacerbation.

Findings from the Foundation for Government Accountability did not net out those who would be eligible for exemptions under CMS rules.

If all states passed their own health insurance mandates similar to ones in New Jersey and Massachusetts, close to 4 million more Americans would have health insurance, and premium costs would drop an average of nearly 12%, according to a recent report from The Commonwealth Fund and the Urban Institute.

Adam Boehler, director of the Center for Medicare & Medicaid Innovation, is taking on an additional role as the senior advisor for value-based transformation and innovation. He represents the last departmental appointment as part of HHS Secretary Alex Azar's 4 priority areas.

Coal worker’s pneumoconiosis (CWP), commonly called black lung, is making a return, especially in central Appalachia, according to a recent study published in the American Journal of Public Health.

A new research study, published in JAMA Cardiology, aimed to further confirm a previous correlation between asthma and atrial fibrillation (AF) and to determine if the degree of asthma control affected the risk of developing AF.

The Trump administration is proposing to pay doctors who take Medicare basically the same amount for office visits regardless of reason; the pending sale of Mission Health to HCA Healthcare reflects a national trend as hospitals consolidate at an accelerating pace and the cost of healthcare continues to rise; a closer look at 5 ideas in President Trump's plan to lower drug prices.

The FDA approved the first targeted therapy for adults with relapsed or refractory acute myeloid leukemia with an IDH1 mutation. In addition, FDA also approved a companion diagnostic to be used to detect the specific mutations in the IDH1 gene.

While the connection between diabetes and cancer has been known, this study was the first to show that women with diabetes face a higher risk than men with the disease.

Acetazolamide, sold under the trade name Diamox, is a drug used to treat altitude sickness, glaucoma, epilepsy, heart failure, and seizures. According to a new study, acetazolamide may also be effective in treating the fast-growing brain tumor glioblastoma.

Researchers observed that migraine was associated with an increased risk of developing a cochlear disorder, especially tinnitus.

New tools from the American College of Chest Physicians' CHEST Foundation, the Allergy & Asthma Network, and the American College of Allergy, Asthma & Immunology can help clinicians and patients to work together to choose the best treatment and increase adherence.

A recent systematic review and meta-analysis published in The Lancet Oncology found that men with advanced cancers respond better than women to treatment with anti-PD-1 or anti-CTLA-4 immune checkpoint inhibitors.

According to a report, existing HIV tools and strategies are insufficient, and despite historic breakthroughs in maximizing prevention and treatment strategies, the HIV pandemic will likely continue to be a global challenge for the foreseeable future.

A recent study published in Radiology found that evaluating the differences in iron accumulation in the deep gray matter of the brain using a magnetic resonance imaging (MRI) technique may help to identify patients with multiple sclerosis (MS) that are at greater risk for disease progression and disability.

A solution has been found to maintain a version of a free government website that has hosted clinical guidelines, but now users will have to pay for access.

For vulnerable populations, their health and healthcare issues may be exacerbated by social factors. Here are just 5 vulnerable populations who experience greater risk factors, worse access to care, and increased morbidity and mortality compared with the general population.

Nearly half of patients visiting urgent care centers who were diagnosed with an acute respiratory condition, for which antibiotics are neither recommended nor effective, walked away with an antibiotic prescription anyway.

Do e-cigarettes help current smokers quit, or do they just become an additional nicotine habit? A new study of more than 30,000 adults in Sweden indicates that traditional smokers use both methods.

Coverage of our peer-reviewed research and news reporting in the healthcare and mainstream press.