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The top 5 most-read conference stories of 2020 on AJMC.com included stories about study results on the impact that new therapies are having on cardiovascular and renal health.

In a year in which health care professionals were forced to alter treatment plans to adjust to an ongoing health crisis, the majority of our most popular ophthalmology stories of 2020 involved the intersection of ophthalmologic care and coronavirus disease 2019.

The top 5 most-read respiratory stories of 2020 on AJMC.com largely focused on the treatment options and risks associated with idiopathic pulmonary fibrosis (IPF) as well as how mental health and asthma are related.

Migraine accounts for many billions of dollars in direct and indirect health care costs, said Peter McAllister, MD, a neurologist, board certified headache specialist, and medical director of the New England Institute for Neurology and Headache.

Tomatoes metabolically engineered to be enriched by the antiparkinsonian drug levodopa may provide a novel, cost-effective source of the drug for patients with Parkinson disease.

The top 5 most listened-to podcasts spanned a range of health topics, including key 2020 election concerns among stakeholders, the use of applied machine learning to predict health care utilization, and real-world evidence on biomarker testing in colon cancer.

In a cohort study of nurses, irregular and long menstrual cycles throughout life were associated with a greater risk of type 2 diabetes (T2D).

Two story lines predominated renal news in 2020: coronavirus disease 2019's effect on the kidneys and the overwhelming benefits of sodium-glucose cotransporter 2 inhibitors for those with chronic kidney disease and type 2 diabetes.

Researchers discuss recent insights on the relationship between sleep-disordered breathing (SDB) and atrial fibrillation (AF), particularly how proper SDB management can reduce the incidence, burden, and recurrence of AF.

Recent study findings highlight mixed results following use of this medication among Mississippi and Massachusetts Medicaid beneficiaries.

The coronavirus disease 2019 (COVID-19) pandemic dominated headlines for much of 2020, and most of the top 5 multiple sclerosis articles of this year discussed the effects of COVID-19 on patients with this disease. Others touched on physician and patient assessments of relapse and potential new treatments for neural damage.

Immunosuppressed patients who had an autoimmune disease (AD) were significantly less likely to develop severe acute respiratory distress syndrome (ARDS) compared with patients who were not immunosuppressed and did not have an AD.

The top 5 most-read stories about spinal muscular atrophy (SMA) of 2020 on AJMC.com focused on a new treatment option for SMA and whether gender or gene mutations have any effects on the disease.

In addition to significant morbidity and impaired health-related quality of life, patients with atopic dermatitis have a significant out-of-pocket (OOP) financial burden related to their disease.

A study from Denmark found that low health literacy was not a risk factor for mortality in patients with chronic obstructive pulmonary disease (COPD) compared with the general population and patients with other chronic conditions.

The top 5 most-read stories of 2020 about rare diseases on AJMC.com focused mainly on new and noteworthy treatment options for a variety of conditions.

Although research has cemented BMPR2 mutations as having associations with the development of pulmonary arterial hypertension, the germline mutations are not the only culprit.

The top 5 most-read news stories for Evidence-Based Oncology™ (EBO), a publication of The American Journal of Managed Care®, ranged from drug approvals to policy challenges and targeted therapies.

Our most-popular articles relating to migraine in 2020 included new research on menstrual migraine and the efficacy of erenumab, a calcitonin gene-related peptide inhibitor, for migraine.

Our top heart failure articles of the year cover a groundbreaking development for dapagliflozin, address the important issue of disparities in this space, and see coronavirus disease 2019 make yet another appearance.

Recent major investments signal growth in an emerging therapeutic sector.

Both secukinumab 300 mg and secukinumab 150 mg significantly improved signs and symptoms of axial disease in patients with psoriatic arthritis (PsA) who had inadequate response to non- steroidal anti-inflammatory drugs.

The distinction between valvular and nonvalvular atrial fibrillation (AF) has been a persistent point of confusion for clinicians.

Verana Health, along with the FDA, the American Glaucoma Society, and American Academy of Ophthalmology, recently announced the launch of the Patient-Reported Outcomes for Minimally Invasive Glaucoma Surgery study with the first patient enrolled.

Among patients with Parkinson disease, a positive history of essential tremor was found to be associated with slower progression of motor and nonmotor symptoms, with no impact observed on survival.

In 2020, articles published in The American Journal of Accountable Care® (AJAC) explored drivers of success in accountable care organizations, responses to payment reform efforts, and more.

Researchers are studying the blood of Robert K. Massie, Jr, PhD, MA, Society for Progress, who was born with severe factor VIII hemophilia and contracted HIV and hepatitis C from contaminated blood products. He did not require antiretrovirals until undergoing a liver transplant a decade ago.

Most patients with bone metastases or multiple myeloma (MM) who are hospitalized with skeletal-related events require lengthy and costly follow-up care after they are discharged.