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Assessing 4 dose levels of carfilzomib, researchers have determined that the drug, in combination with thalidomide and low-dose dexamethasone, is highly safe and effective in transplant-eligible patients with newly diagnosed multiple myeloma.

The findings represent the first in a new wave of renal outcomes trials in the sodium glucose co-transporter 2 (SGLT2) inhibitor class, a game-changing group of type 2 diabetes drugs with many benefits beyond lowering blood glucose.

A new study has found that prevalence rates of chronic obstructive pulmonary disease varied by occupation.

Senator Bernie Sanders, I-Vermont, has reintroduced a Medicare for All bill while other Democrats eye an alternative; the Trump administration is appealing a federal judge's decision to toss out Medicaid work requirements in Kentucky and Arkansas; AIDS activists are pushing CDC to force Gilead to give the agency royalties for Truvada.

This week, the Institute for Clinical and Economic Review (ICER) released a Draft Evidence Report assessing the clinical effectiveness and value of 2 potential drug therapies to treat individuals with peanut allergy.

A study of gay and bisexual men found that incidence of sexually transmitted infections (STIs) increased following pre-exposure prophylaxis (PrEP) initiation.

Rising consumerism, new competition, and payment models designed to keep patients out of acute care are forcing hospital-centric enterprises to rethink their delivery models. Organizations that excel in building integrated care delivery ecosystems and lasting consumer relationships based on a differentiated brand promise and superior outcomes will be the ones that find success.

The fourth annual Numerof Survey Report outlined the evolution of population health management in the United States. The report found that while the population health management has been gaining momentum, initiatives toward adopting risk-based models have stalled.

The American College of Physicians has updated their breast cancer screening guidelines to recommend that women of average risk of breast cancer get a mammogram at age 50 and every other year; the FDA advised clinicians against aburptly halting opioid prescribing for patients with chronic pain; New York’s mayor declared a public health emergency over the state’s measles outbreak.

The program comes as Congress has singled out the cost of insulin in its scrutiny of drug prices. Patients with type 1 diabetes cannot survive without the hormone, and press reports have highlighted the plight of young adults who ration insulin after they reach age 26 and cannot stay on family insurance plans.

Pharmacy benefit manager executives told members of the Senate Finance Committee that rebates are not the cause of high drug prices, and that more must be done to end evergreening and pay-for-delay tactics. Senators were skeptical.

FDA has approved a monoclonal antibody to treat postmenopausal women who have a higher risk of bone fracture.

A study found that children with respiratory infections were more likely to receive antibiotics and less likely to receive guideline-concordant antibiotic management during a telemedicine visit compared with an urgent care or primary care visit.

New light has been shed on incidents of violence against hospital workers; nutrients from food, as opposed to those from dietary supplements, have been associated with lower cancer death rates; a new smoking intervention doubled smoking cessation rates among individuals with mental health conditions.

Oncologists and hematologists are welcoming a clarification from the CDC about the use of opioid pain relief for patients with cancer, past cancer, or sickle cell disease, and they are hopeful that payers see the update so that patients in pain are not denied or delayed relief.

The results come as US professional societies are updating primary prevention guidelines in cardiology.

In the past 5 decades, there has been a steady rise in the prevalence of multiple sclerosis (MS), according to estimates using a validated algorithm across 5 large US administrative health claims data sets. The research was published in Neurology.

The Trump administration is planning an Affordable Care Act replacement plan; a drug-resistant fungus has been spreading and causing severe issues for hospitals; protesters gather in Washington, DC, to criticize the FDA's handling of the opioid crisis.

Genetic alternations in colorectal cancer (CRC) are linked to different survival and treatment outcomes, according to a study that used next-generation sequencing (NGS) of tumor DNA. The study was published in Journal of Clinical Oncology.

"Watch and wait” is typically used first for asymptomatic patients with myelofibrosis, according to a retrospective review of management strategies from the United Kingdom.

A recent study conducted in mice found that the ability of cells to use glucose can actually help to regulate the immune system during lung inflammation.

There may be a difference between controlled burns and wildfires on one’s immune system.

A study of patients with multiple myeloma in a real-world setting found that adherence to immunomodulatory drugs (IMIDs) is high across all 3 options of the drugs.

E-cigarettes have become increasingly popular in the United States since their introduction in 2007. Reported use has dramatically increased among adults and, alarmingly, youths, as well. Sales of e-cigarettes, other vaping devices, and e-liquids have increased nearly 1400% over the last decade.

Rising healthcare costs and challenges with access to care have given rise to innovations in healthcare and new partnerships. Now, Blue Cross and Blue Shield of North Carolina (Blue Cross NC) is partnering with Duke University Health System (Duke Health) to create a new health insurance company to meet the needs of seniors.

Coverage of our peer-reviewed research and news reporting in the healthcare and mainstream press.

After leaving the FDA, Commissioner Scott Gottlieb, MD, will return to conservative think tank American Enterprise Institute; the Trump administration is urging Alaska to become the first state to change its Medicaid program funding to a block grant; CVS is expanding its same-day prescription delivery service to 36 states and Washington, DC.