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Joneigh Khaldun, MD, MPH, FACEP, vice president and chief health equity officer for CVS Health, speaks on the goals of the Community Equity Alliance in improving health care disparities, particularly for cardiovascular health and mental health outcomes, within underserved communities.

There are 2 ranibizumab biosimilars approved in the United States, and with more ranibizumab and the first aflibercept biosimilars on the horizon, gaps in knowledge among retinal physicians should be addressed.

Patients with myelofibrosis (MF) who achieved a spleen response while taking ruxolitinib and lost it had survival outcomes similar to patients who did not respond, according to results from a real-world study.

A different type of test may improve diagnosis for some patients with myasthenia gravis (MG).

Senators concerned over health care worker shortages; Medicaid beneficiaries left unaware of renewal deadline; Ohio to open health clinic after toxic train derailment.

The authors identified 2 subgroups with non–small cell lung cancer (NSCLC) who had different responses to common cancer therapies.

An increased risk of hospitalization for more than 6 days due to community-acquired infections was associated with male sex and admittance to the Pulmonology or Surgery department, with risk shown to differ according to pathogen.

The second half of 2022 brought the first gene therapies for hemophilia to the market in both the United States and abroad.

Relugolix was frequently used in combination with other medications for prostate cancer in patients both new to androgen-deprivation therapy and continuing androgen-deprivation therapy in a real-world study.

Investigators note that although the overall cost for implementing next-generation sequencing (NGS) testing would be more than implementing current polymerase chain reaction (PCR)–based testing, the assay may be more cost effective overall because it screens for multiple conditions.

The results of the futility analysis also suggest the therapy leads to significant clinical benefits.

Despite coming at a high cost, an analysis found that in some cases, chimeric antigen receptor T-cell therapy may be cost-effective compared with the standard of care in the second line or later for relapsed or refractory diffuse large B-cell lymphoma (R/R DLBCL).

An HIV prevention and treatment program implemented in Zambian criminal justice facilities demonstrated high levels of pre-exposure prophylaxis (PrEP) uptake among at-risk individuals.

Geographic atrophy is a leading cause of blindness. The new approval will help to fill an unmet need for patients.

Patients with acute respiratory distress syndrome (ARDS) second to COVID-19 improved with early continuous positive airway pressure (CPAP) and high-flow nasal cannula (HFNC) treatment, a study finds.

Patients with heart failure and high comorbidity burdens who received postdischarge noninvasive telemonitoring and nurse telephone coaching showed better survival outcomes than those who received standard care.

The glycemia risk index (GRI) showed that pediatric patients and those receiving continuous subcutaneous insulin infusion had higher overall component of hypoglycemia than adults and those receiving multiple doses of insulin.

This review and meta-analysis included 34 studies covering 1762 patients, and investigated the efficacy of 4 varieties of dietary treatment for eosinophilic esophagitis (EoE).

The data showed that most doses of nusinersen were received on time while also underscoring the importance of being meticulous with the methodological approaches used with real-world databases for evaluating treatment patterns.

Coverage of our peer-reviewed research and news reporting in the health care and mainstream press.

The Biden administration sends medical experts to the site of the derailed train carrying hazardous materials in Ohio; senators push for pharmacy benefit manager (PBM) reforms; Kentucky Supreme Court proceeds with near-total abortion ban.

At Carolina Blood and Cancer Care Associates, the No One Left Alone (NOLA) initiative is working to break down cancer health disparities among its patients by addressing the social determinants of health that may be preventing equitable access to care.

The southeastern areas of the country have worse health outcomes and health-related quality of life (HRQOL) compared with other parts of the United States, with high rates of diabetes, obesity, cancer, and cardiovascular disease.

Long-term results show sustained benefit from the immunotherapy-TKI combination for patients with metastatic renal cell carcinoma regardless of risk profile or PD-L1 status.

When the first adalimumab (Humira) biosimilar launched at the end of January, it was just the beginnings of a wave of coming biosimilars for anti-inflammatory biologics.

While there are a number of treatments available for diabetic kidney disease (DKD), the biggest limitation is the lack of early detection, said Daniel E. Weiner, MD, MS, board certified nephrologist and lead navigator at Tufts Clinical and Translational Science Institute.

Social Security and Medicare spending could double by 2023; FDA panel experts want naloxone to be available over the counter after the drug information is revised; Moderna announced its COVID-19 vaccines will stay free, and the Biden administration might keep tests and treatments free for the uninsured.

The authors say newer treatment options for small cell lung cancer (SCLC) may lead to improvement in this area of high unmet need.