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Among patients with type 2 diabetes (T2D) and weight issues, cognitive advantages that women hold over men when both are affected are preserved into later life but are eroded for women carrying apolipoprotein E ε4 alleles.

Based on their analysis, the researchers compiled a recommended number of genes to include in panels for 14 cancer types.

Given that some patients may need to travel out of state to access CAR T sites of care, some may not have a clear understanding of their insurance benefits, including requirements for out-of-state or out-of-network treatment, as well as adequate assistance with the costs of medical-related travel.

The researchers credit wider availability of molecular testing and better understanding of the diseases for the emerging targeted therapies in development.

Three cell and gene therapies were among the drugs included in a specialty drugs pipeline forecast at the Academy of Managed Care Pharmacy 2021 meeting.

Investigators found a potential link between chronic obstructive pulmonary disease (COPD) and greater risk of experiencing stroke and myocardial infarction in patients with hypertension.

Changes to naming conventions and interchangeability labels are just some of the regulatory barriers standing in the way of biosimilar uptake, according to Kaiser Permanente researchers.

Megan Olsen, MPH, principal at Avalere, discussed how gene and cell therapies can offer new treatment options for patients with cancer.

This recent study out of Japan compared the use of renin-angiotensin system inhibitors and β-blockers among patients with heart failure, both those who had physical limitations and those who did not.

Atopic dermatitis has a tremendous affect on quality of life, so it’s nice to have more options to treat patients in a different way, noted Lawrence F. Eichenfield, MD, chief of pediatric and adolescent dermatology at Rady Children's Hospital-San Diego.

Over a 14-year period, active-duty US military members reported a marked 45-fold increase in rates of insomnia and 30-fold increase in rates of obstructive sleep apnea.

Coverage of our peer-reviewed research and news reporting in the health care and mainstream press.

Study quantifies risk of blood clots in patients with COVID-19; Biden administration aims to reverse restrictions on fetal tissue research; Michigan hospitals struggle to care for COVID-19 cases.

This week, the top managed care news included a pause in distribution of J&J’s COVID-19 vaccine; FDA clears first AI device to find possible cancerous hot spots during colonoscopies; lessons from years of public health budgetary neglect.

Symptoms of sleepwalking and/or REM sleep behavior disorder in men were significantly associated with higher odds of having Parkinson disease (PD), with PD-related neurodegeneration potentially impairing arousal regulation during sleep.

Rebecca Borgert, PharmD, BCOP, and Jim Rebello, PharmD, from Magellan Rx Management, discussed what evidence they believe could persuade payers to include biosimilars as preferred formulary products.

Data from a recent cross-sectional study show severity of atopic dermatitis (AD) is associated with prevalence of learning disorders among children.

A poster at the Academy of Managed Care Pharmacy 2021 meeting examined the impact of high-deductible health plans (HDHPs) on access to health care and resource use in the United States and the interaction of race, ethnicity, and income.

Study results indicate a possible relationship between diabetic kidney disease (DKD) and frailty and risk of subsequent delirium and cognitive impairment.

The review comes amid growing attention directed at identifying treatments that can prevent progression of polycythemia vera (PV) to myelofibrosis or an aggressive form of acute myeloid leukemia.

Ilumya (tildrakizumab) was shown to be safe and effective in controlling moderate to severe psoriasis for adults through 5 years of treatment in a recent study.

Students attending middle school and high school exhibited significantly improved sleep duration and daytime sleepiness with later school start times, while elementary school students were shown to be minimally affected by earlier start times.

Elevated levels of 2 inflammatory biomarkers may indicate a greater heart failure hospitalization risk for patients who have diagnosed atrial fibrillation.

The in vitro study of melanoma cells analyzed the molecular mechanisms of the pair of proteasome inhibitors, finding that they reduced B16-F1 tumor growth.

Karen Coderre, PharmD, and Madhavi Manduru-Rao, PharmD, detail how CMS' increased weighting for Consumer Assessment of Health Care Providers and Systems surveys impacts Star ratings.

The pandemic reduced visits to specialists last year, which in turn reduced the volume of prescriptions, according to a presentation at the Academy of Managed Care Pharmacy 2021 meeting.

A new study finds high rates of suicide among female nurses in the United States; President Joe Biden aims to undo Trump-era restrictions on abortion referrals; research indicates regular exercise may prevent severe COVID-19 outcomes.

This is a case study of a male patient with Fabry disease who presented with severe anaphylaxis following re-initiation of full-strength treatment with intravenous agalsidase beta (Fabrazyme).