Clinical

A new study questions the maximum-tolerated-dose approach in cancer.

There are multiple barriers to accessing innovative oncology care from the design of healthcare benefits to a patient’s position on the federal poverty level, explained Daniel J. Klein, president and CEO of the Patient Access Network (PAN) Foundation.

What we're reading, February 25, 2016: the government will require proof of eligibility for enrollment in special sign-up periods under the Affordable Care Act (ACA); this year's flu vaccine is more effective; and 6 states are suing the Obama administration over an ACA fee.

The presence of interstitial lung abnormalities is linked to an increased risk of death, according to a new research published in JAMA.

Detecting acute HIV infections is important because this infection contributes disproportionately to the transmission of HIV and highly contagious.

Emergency room overutilization is a significant issue in oncology care and may increase healthcare expenditures while lowering the quality of patient care.

A collaborative study conducted across cancer treatment centers in the United States has identified malignant brain tumors as the most common cause of cancer-related deaths in adolescents and young adults aged 15 to 39 years.

With a vote of 89-4, the Senate confirmed Robert Califf, MD, for the position of FDA commissioner.

What we're reading: drug makers are not reporting complete information about side effects; Johnson & Johnson will pay $72 million to the family of a woman who blamed her ovarian cancer on talcum powder; and Maine and Utah make new attempts at expanding Medicaid.

Experts and biological researchers aren’t completely convinced with the president's cancer moonshot initiative and the released budget.

Survival in children with acute lymphoblastic leukemia could be significantly influenced by their family’s socioeconomic status, a new study published in Pediatric Blood and Cancer has found.

A national survey of physicians found strong support for key policies that could help prevent opioid misuse, but report encountering barriers.

A healthcare delivery model that utilizes home visits and that is interdisciplinary and team-based has been shown to improve care while controlling costs for patients with complex needs

The full slides from the 2015 Patient-Centered Diabetes Care keynote speech, where Robert A. Gabbay, MD, PhD, discussed new care models being implemented to improve patient health in the long term.

A new report by the American Cancer Society points to disparities in cancer survival between whites and blacks for certain cancers, although the reasons for these differences remain unconfirmed.

What we're reading, February 23, 2016: drug spending for CVS health plans slowed from 11.8% to 5%; CDC Director Tom Frieden, MD, MPH, talks Zika virus; and an investigation into the HealthCare.gov launch found widespread mismanagement.

The supplemental new drug application submitted by Pfizer, the drug's manufacturer, included phase 3 results from the PALOMA-3 trial.

Risk adjustment for social determinants of health could reduce penalties to children’s hospitals for patient factors that are beyond their control, according to the results of a new study published in JAMA Pediatrics.

The American Journal of Managed Care's co-editor-in-chief A. Mark Fendrick, MD, director of the University of Michigan Center for Value-Based Insurance Design (VBID), is testifying on how the principles of VBID and clinical nuance can contribute to healthcare reform in the US military health system.

What we're reading, February 22, 2016: new legislation proposes placing a 3-year moratorium on advertising newly approved drugs; the prevalence and incidence of stroke among young adults has increased significantly; and more women with breast cancer are choosing outpatient mastectomies.

Support from at least 60 senators during today's procedural vote will ensure a final confirmation vote for Robert Califf, MD, likely Tuesday.

Patients with mental illness can be a very difficult population to treat and programs need to be established that properly meet the health needs of these patients, said Dana Goldman, PhD.

A report card evaluating the healthcare being provided to the aging US population found that the use of evidence-based practices widely varies across the country.

This week's top managed care stories included the release of 7 core sets of quality measures, more evidence that value-based insurance design works to lower costs, and the FDA assigns breakthrough designation to AstraZeneca's PD-L1 inhibitor.

Two studies presented at the ongoing 2016 Multidisciplinary Head and Neck Cancer Symposium report on financial hurdles faced by patients diagnosed with head and neck cancer that result in lifestyle modifications, advanced disease, and worse outcomes.

What we're reading, February 19, 2016: long-term hospice care is weighing on Medicare; both the pope and the World Health Organization suggest women in Zika infected countries have access to contraception; and Texas health official steps down after co-authoring study on Planned Parenthood.

While primary care physicians are incorporating more nurse practitioners and physicians' assistants into patient care teams, there is a lack of incorporation of other healthcare professionals, such as behavioral specialists, psychiatrists, and pharmacists.

A study of decade-long trends in the incidence and mortality rates of patients who develop cardiogenic shock during hospitalization for acute myocardial infarction found a decline in death rates, but not incidence.

A new study, published in Nature Communications, has delineated a mechanism that could help explain the resistance that is emerging with the new immuno-oncology agents such as PD-1 and PD-L1.

Employers can encounter complications with benefit design approaches when it comes to those patients for whom traditional, less-expensive drugs are ineffective, or for those who prefer to have the drugs administered differently, explained Cheryl Larson, BA, vice president of the Midwest Business Group on Health.