Health Care Delivery

Sattva S. Neelapu, MD, professor and deputy department chair in the Department of Lymphoma/Myeloma in the Division of Cancer Medicine at the University of Texas MD Anderson Cancer Center, discusses findings of the ZUMA-12 study examining axicabtagene ciloleucel (axi-cel) as a first-line treatment option for high-risk patients with large B-cell lymphoma.

Mark Wildgust, PhD, vice president, Global Medical Affairs, Oncology, Janssen, speaks on progression-free survival, complete response, and overall survival benefits observed with ciltacabtagene autoleucel (cilta-cel) in CARTITUDE-1 and other studies presented at the 63rd Annual American Society of Hematology Meeting and Exposition.

Andre Goy, MD, MS, chairman and executive director of the John Theurer Cancer Center, speaks on molecular features of diffuse large B-cell lymphoma and how this explains differences in patient response for chemotherapy and chimeric antigen receptor (CAR) T-cell therapy.

Constantine S. Tam, MBBS, MD, consulting hematologist and associate professor, Peter MacCallum Cancer Centre, discusses the superior safety and progression-free survival outcomes from the SEQUOIA phase 3 trial, which compared zanubrutinib with bendamustine and rituximab combination therapy in treatment-naive chronic lymphocytic leukemia/small lymphocytic lymphoma.

Investigators discuss the humoral response to enzyme-replacement therapy in their review of the clinical picture and diagnostic confirmation of Fabry disease.

Findings about the willingness of primary care providers to prescribe artificial pancreas systems have positive implications for increasing access to and reducing disparities around this technology by alleviating the need to see a specialist.

Posters review how a patient’s neighborhood impacts access to the liver transplant waitlist and how Medicaid expansion improved waitlist mortality.

High-flow nasal therapy overcomes some of the barriers associated with noninvasive ventilation, making the novel support beneficial for patients with acute exacerbations of chronic obstructive pulmonary disease (COPD).

Researchers at the University of Rochester are analyzing facial muscle movements through videos taken over webcams or smartphones to train a machine learning algorithm with the hope that it can predict Parkinson disease at an earlier stage.

Results presented Saturday at the annual meeting of the American Society of Hematology show significant benefits in event-free survival, progression-free survival, and complete response over standard of care.

A case series of corrective surgeries in children with severe scoliosis due to spinal muscular atrophy (SMA) type 1 showed a positive success rate, but with significant postoperative complications.

This new review examined oral health outcomes in children with growth hormone deficiency (GHD) following a search of the published literature from January 2000 through May 2021.

Although pulmonary arterial hypertension (PAH) is a rare occurrence in systemic lupus erythematosus (SLE), a recent report details efforts by researchers to find an easy way to identify predictive factors, since having both diseases together reduces overall survival.

Guidelines recommend patients with nonalcoholic fatty liver disease (NAFLD) who are obese achieve 5% to 10% weight loss to prevent NAFLD progression.

Many postoperative readmissions are amenable to diversion to a hospital at home program for surgical patients, representing an opportunity to generate revenue and improve patient experience.

Andre Goy, MD, MS, chairman and executive director of the John Theurer Cancer Center, provides an overview of the emerging data at ASH 2021 on CAR T-cell therapy as a second- and first-line treatment.

The CDC’s latest Morbidity and Mortality Weekly Report details the care and HIV service disparities that persist among sexual minority men.

The findings, said the researchers, are an important step toward achieving glucose control with a fully automated closed-loop system for patients with type 1 diabetes.

Pfizer predicts that a fourth dose of a COVID-19 vaccine may be needed to quell the Omicron variant; CMS officials share figures on enrollment for health coverage under the Affordable Care Act (ACA); City of Hope announces acquisition of Cancer Treatment Centers of America.

High-intensity interval training (HIIT) may maintain health, including immune cell function, for patients with treatment-naïve chronic lymphocytic leukemia (CLL).

Nail involvement was shown to reduce the effectiveness of ustekinumab in the treatment of moderate to severe psoriasis, whereas secukinumab exhibited overall higher efficacy than ustekinumab and similar response rates regardless of nail involvement.

Children aged 6 to 11 years had reduced asthma exacerbations and improved lung function and asthma control when on dupilumab for a year.

Children with uncontrolled asthma had a 3- to 6-times the risk of hospitalization for COVID-19, the investigators found.

On this episode of Managed Care Cast, guests discuss why pharmacists are in a unique position to help address social determinants of health (SDOH) and the importance of incorporating patients’ perspectives into research agendas.

British study finds higher immune response when mixing Pfizer, AstraZeneca COVID-19 vaccines with Moderna; World Health Organization strongly advises against the use of convalescent plasma to treat COVID-19; disparities in pay by gender among physicians.

Results of a systemic review found evidence potentially supporting the use of smart phone applications among mothers with gestational diabetes.

Early data suggest the Omicron variant may cause less severe cases of COVID-19; a new JAMA study finds the average young adult overweight; spotlighting vaccine discrimination in Africa.

Peter Dicpinigaitis, MD, professor of medicine at the Albert Einstein College of Medicine and director of the Montefiore Cough Center, discusses what he and others have seen during the pandemic in patients with chronic cough who had COVID-19.

Setting up a palliative care consultation program for patients with acute myeloid leukemia (AML) improved some aspects of care.

Multidisciplinary care that includes growth hormone treatment should not cease once patients with Prader-Willi syndrome reach adulthood, according to authors of a study on care outcomes.