
Opinion|Videos|July 19, 2024
ASCO 2024: DREAMM-8 Study of Belantamab Mafodotin, Pomalidomide, and Dexamethasone
Author(s)Alfred L. Garfall, MD
Alfred L. Garfall, MD, discusses follow-up data from the DREAMM-8 study presented at ASCO 2024.
Advertisement
Video content above is prompted by the following questions:
- Discuss the data presented at ASCO 2024 on the DREAMM-8 study (NCT04484623) of belantamab mafodotin plus pomalidomide and dexamethasone (BPd) vs pomalidomide plus bortezomib and dexamethasone (PVd) in patients with relapsed/refractory multiple myeloma (RRMM). (
Abstract )- What was the objective of this study?
- How was this study designed/what methodology was used?
- What results were presented?
- N=155
- Median follow-up: 21.78 months
- PFS
- ORR
- Median duration of response
- OS
- Safety
- Please provide your key takeaways from this study.How might these findings impact the management of patients with RRMM?
- Belantamab mafodotin was previously withdrawn from the US market for RRMM following results from the phase 3 DREAMM-3 trial (NCT04162210) which did not meet its primary endpoint of progression-free survival (PFS). How do the results of the DREAMM-8 trial shed light on potential advantages of BPd in patients with RRMM?
Newsletter
Stay ahead of policy, cost, and value—subscribe to AJMC for expert insights at the intersection of clinical care and health economics.
Advertisement
Latest CME
Advertisement
Advertisement
Trending on AJMC
1
Dual JAK Inhibition Demonstrates Efficacy in Progressive Nonsegmental Vitiligo
2
Nerandomilast a "No-Brainer" for First-Line Pulmonary Fibrosis Therapy: Justin M. Oldham, MD, PhD, MS
3
FDA Grants Breakthrough Therapy Designation to R-DXd in CDH6-Expressing Ovarian Cancer
4
FDA Approves Guselkumab for Pediatric Plaque Psoriasis, Active Psoriatic Arthritis
5