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Opinion|Videos|May 22, 2024

Genetic Aspects of Alzheimer Disease

Author(s)Derek van Amerongen, MD, MS, Soeren Mattke, MD, DSc, B. Joy Snider, MD, PhD

The panel provides an overview of genetic factors associated with Alzheimer disease and the genetic mutations that contribute to the pathophysiology of the disease.

Episodes in this series

A panel of 5 experts on Alzheimer disease

EP. 1 The Clinical and Economic Implications of Alzheimer Disease Across Patients, Families, and the Health Care System

B. Joy Snider, MD, PhD, and Maria Lopes, MD, MS

EP. 2 Recent Insights into the Pathophysiology of Alzheimer Disease

A panel of 5 experts on Alzheimer disease

EP. 3 Genetic Aspects of Alzheimer Disease

A panel of 5 experts on Alzheimer disease

EP. 4 The Patient Experience: From Symptoms to Diagnosis of Alzheimer Disease

Video 5 - "Potential Consequences of Early Diagnosis of Alzheimer Disease"

EP. 5 Potential Consequences of Early Diagnosis of Alzheimer Disease

Video 5 - "Potential Consequences of Early Diagnosis of Alzheimer Disease"

EP. 6 Criteria for Diagnosing Alzheimer Disease and the Role of Testing

A panel of experts on Alzheimer's disease

EP. 7 Exploring the Economic Impact of Advanced Approaches for Diagnosing Alzheimer Disease

A panel of experts on Alzheimer's disease

EP. 8 Clinical Impact of the Introduction of Disease-Modifying Treatments for Alzheimer Disease

A panel of experts on Alzheimer's disease

EP. 9 Clinical Decision-Making for Alzheimer Disease Management

A panel of experts on Alzheimer's disease

EP. 10 Cost, Value, and Affordability of Treatment for Alzheimer Disease

A panel of 5 experts on Alzheimer disease

EP. 11 Advancements in Alzheimer Disease Treatment: Emerging Drug Candidates

A panel of 5 experts on Alzheimer disease

EP. 12 Exploring the Influence of Administration Routes on Medical Costs and Caregiver Burden

A panel of 5 experts on Alzheimer disease

EP. 13 Payer Coverage Considerations for New Treatments for Alzheimer Disease

A panel of 5 experts on Alzheimer disease

EP. 14 Concluding Remarks: Impact of Alzheimer Disease, Promising Treatments in Development, and Future Outlook

[Dr Snider] Discuss the genetic factors associated with AD. How do mutations in genes such as APP, PSEN1, and PSEN2 contribute to the pathophysiology of the disease? How do different alleles of APOE4affect risk of developing AD?

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