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Merck to Present Data on The First FDA-Approved PD-1 Inhibitor: Pembrolizumab
As the immuno-oncology landscape intensifies, a second player in the game, Merck's PD-1 inhibitor pembrolizumab (Keytruda), was recently approved for the treatment of advanced, unresectable melanoma.
As the immuno-oncology landscape intensifies, a second player in the game, Merck’s PD-1 inhibitor pembrolizumab (Keytruda), was recently approved for the treatment of advanced, unresectable melanoma, in patients who are resistant to ipilimumab and to a BRAF inhibitor (if they harbor a BRAFV600 mutation). A press release by Merck on November 6, 2014, announced that results of studies evaluating pembrolizumab against chemotherapy, in advanced melanoma, will be presented at the Society for Melanoma Research, 2014 International Congress in Zurich, Switzerland, on November 16, 2014.
The late breaker oral session, “A Randomized Controlled Comparison of Pembrolizumab (MK-3475) and Chemotherapy in Patients with Ipilimumab-Refractory Melanoma,” will be presented by Dr Antoni Ribas, associate professor at the Jonsson Comprehensive Cancer Center, University of California at Los Angeles.
“Our focus on evaluating Keytruda as a monotherapy is enabling Merck to rapidly advance the clinical development of our anti-PD-1 therapy,” said Dr Roy Baynes, senior vice president, Global Clinical Development, Merck Research Laboratories, in the press release. “We look forward to the first comparative data in advanced melanoma being presented. We continue to expand our immuno-oncology clinical program with Keytruda both as monotherapy and in combination with other agents.”
Merck is currently testing the antibody in a variety of cancers, including advanced triple-negative breast cancer, classic Hodgkin Lymphoma, and bladder cancer.
Award-Winning Poster Presentations From AMCP 2024
April 23rd 2024At the Academy of Managed Care Pharmacy (AMCP) 2024 annual meeting, multiple poster presentations concerned with health equity, data collection, glucagon-like peptide-1 agonists, and more were acknowledged for their originality, relevance, clarity, bias, and quality.
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The Importance of Examining and Preventing Atrial Fibrillation
August 29th 2023At this year’s American Society for Preventive Cardiology Congress on CVD Prevention, Emelia J. Benjamin, MD, ScM, delivered the Honorary Fellow Award Lecture, “The Imperative to Focus on the Prevention of Atrial Fibrillation,” as the recipient of this year’s Honorary Fellow of the American Society for Preventive Cardiology award.
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Standard Criteria for Loss of Ambulation Needed in DMD
April 19th 2024A recent study suggests the differences between ambulation definitions for patients with Duchenne muscular dystrophy (DMD) can impact the identification of ambulant vs nonambulant individuals, and standard criteria across settings are needed.
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Promoting Equity in Public Health: Policy, Investment, and Community Engagement Solutions
June 28th 2022On this episode of Managed Care Cast, we speak with Georges C. Benjamin, MD, executive director of the American Public Health Association, on the core takeaways of his keynote session at AHIP 2022 on public health policy and other solutions to promote equitable health and well-being.
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An Overview of Health Care and Pharmaceutical Trends, 2023-2024
April 19th 2024Douglas M. Long, BA, MBA, was featured as the keynote speaker on the closing day of The Academy of Managed Care Pharmacy 2024 annual meeting, with a session dedicated to surveying the health care and pharmaceutical trends of the last year.
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