Video content above is prompted by the following questions:
How has the story of CLL treatment evolved in recent history? What are the latest trends and innovations you have observed in the treatment and management of CLL leading up to ASCO 2024?
Coming into ASCO 2024, what would you consider to be the largest unmet needs in the treatment and management of CLL?
Results from the phase 3 DeLLphi-305 trial, presented at ESMO 2026 and published in the New England Journal of Medicine, showed median overall survival of 21.1 months with the combination vs 12.7 months with durvalumab alone.
SGLT2 inhibitors were linked to hemoglobin gains of about 1.0 to 1.6 g/dL in small MDS and MPN studies, but a review found no randomized trials to confirm.
The authors found concurrent growth in pharmacy benefit manager market concentration and worsening of patient access measures across states from 2016 to 2025.