
Studies With Potential to Change the Science of Heart Failure Management
These 4 studies were pegged as “ones to watch” during the American College of Cardiology (ACC) annual briefing on results for consumers. They will be presented in the opening session of late-breaking clinical trial results on day 1 of ACC.21.
Results from several late-breaking clinical trials will be presented in the opening session on day 1 of ACC.21, the
In the ACC’s annual consumer briefing, ACC.21 Vice-Chair Douglas Drachman, MD, the Corrigan Minehan Heart Center Director of Education and the Teresa G. and Ferdinand F. Martignetti Endowed Chair for Cardiovascular Medicine at the Massachusetts General Hospital, outlined 4 trials to watch.
PARADISE-MI
In this
ADAPTABLE
This
Drachman noted that this trial “may serve as a template for future pragmatic clinical trial design in the real world.”
LAAOS III
Does occlusion of the left atrial appendage during cardiac surgery for another reason work at reducing occurrence of stroke in patients with atrial fibrillation (AFib) on systemic anticoagulants, and do these patients have a lower long-term risk of stroke or systemic embolism?
ATLANTIS
After transcatheter aortic valve replacement (TAV), what is the optimal antithrombotic therapy: systemic anticoagulation or antiplatelet therapies, or a combination of the two? For anticoagulants, is warfarin or a newer non–vitamin K oral anticoagulant preferred, such as a novel oral anticoagulant or direct oral anticoagulant?
To answer these questions,
Newsletter
Stay ahead of policy, cost, and value—subscribe to AJMC for expert insights at the intersection of clinical care and health economics.