Opinion|Videos|January 31, 2025

The Inflation Reduction Act and Cost Considerations for BTK Inhibitors

Name: The Inflation Reduction Act and Cost Considerations for BTK Inhibitors
Uploaded: 2025-01-31T13:00:00.000Z
Duration: AJ9M25S
Description: The Inflation Reduction Act and Cost Considerations for BTK Inhibitors

Author(s)Callie Coombs, MD , Matthew Davids, MD, MMSc , Seema Bhat, MD

Panelists discuss how the inclusion of ibrutinib on the Inflation Reduction Act (IRA) negotiated drug price list could make it a more economically attractive first-line option, potentially influencing the sequencing of Bruton tyrosine kinase (BTK) inhibitors in relapsed/refractory chronic lymphocytic leukemia (R/R CLL) treatment while considering other financial factors like insurance coverage, copays, and total out-of-pocket costs that impact patient access and treatment decisions.

Video content above is prompted by the following:

With ibrutinib on the negotiated drug price list under the IRA, how might cost considerations influence first-line BTK inhibitor selection and subsequently shape second-line and beyond treatment choices in R/R CLL?
Beyond the IRA, what role do broader economic factors, such as insurance coverage and out-of-pocket costs, play in treatment selection for patients with R/R CLL requiring BTK inhibitors?

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The Inflation Reduction Act and Cost Considerations for BTK Inhibitors

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