Opinion|Videos|December 23, 2024

The Pathophysiology of Chronic Graft-Vs -Host Disease (cGVHD) and the Role of CSF1R

Sergio A. Giralt, MD, discusses how the pathophysiology of chronic graft-vs-host disease involves complex immune dysregulation, with CSF1R playing a crucial role in driving the differentiation of monocytes into macrophages, contributing to inflammation and fibrosis in the disease.

Video content above is prompted by the following:

Describe the pathophysiology of chronic graft-vs-host disease and the role of CSF1R in disease pathogenesis.