Understanding Autoimmunity in Type 1 Diabetes and Potential for Therapeutic Opportunities

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Although type 1 diabetes (T1D) includes a reasonably small patient population, it does impose a significant impact on patients, caregivers, payers, and society. This piece explores the history; physical, economic, and psychosocial burden; and clinical pathophysiology of T1D to evaluate opportunities for earlier intervention to change the standard of care for this disease and improve overall outcomes.