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What We’re Reading: Chemotherapy Overdoses; Digital Diabetes Management Tools; Pneumonia Misdiagnosis

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Lack of routine testing can lead to tragic consequences for patients with cancer; an analysis raises questions about clinical benefits of digital diabetes management tools; overuse of antibiotics poses risks to patients with a misdiagnosis of pneumonia.

The Deadly Risk of Chemotherapy Overdoses

Common types of chemotherapy, such as fluorouracil (5-FU) or capecitabine, can be deadly for patients with cancer who are deficient in an enzyme that metabolizes drugs, according to Kaiser Health News. Despite the potential for severe adverse events, including death, routine preemptive testing for patients who may be deficient in the enzyme remains uncommon in the US, with about 3% of American oncologists saying they regularly order the tests before prescribing. While European authorities and some US health care entities have advocated for testing, resistance persists among oncologists, raising questions about patient safety and the need for broader adoption of screening protocols.

Evaluation of Digital Diabetes Management Tools Sparks Debate Over Effectiveness

The Peterson Health Technology Institute (PHTI) recently released a critical analysis of widely used digital diabetes management solutions, casting doubt on their clinical effectiveness and economic impact, according to Fierce Healthcare. The report, which evaluated 8 popular tools, concluded that these solutions fail to deliver significant clinical benefits and may even increase health care spending. While stakeholders acknowledged the need for rigorous evaluation of digital health tools, debates have arisen over the methodology and conclusions drawn by the PHTI, signaling a broader discussion about the standards for assessing digital health innovations.

High Rate of Inappropriate Pneumonia Diagnoses in Michigan Hospitals

A recent study sheds light on the prevalence of inappropriate pneumonia diagnoses in Michigan hospitals, raising concerns about the overuse of antibiotics and potential harm to patients, according to CIDRAP. The findings indicated that 12% of patients were inappropriately diagnosed with pneumonia, with older patients and those with dementia being the most affected. Alarmingly, nearly 88% of patients with an inappropriate diagnosis received full courses of antibiotics, increasing the risk of antibiotic-associated adverse events and contributing to antibiotic resistance.

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