Previous phase 3 studies have demonstrated the efficacy of nebulized glycopyrrolate inhalation solution (GLY) for treating patients with chronic obstructive pulmonary disease (COPD). In a recent study, researchers conducted a secondary analysis and found that nebulized GLY demonstrated efficacy and was well tolerated for up to 48 weeks in subjects with COPD with or without background long-acting beta2-agonist (LABA).
A study found a lack of consistent and comprehensive coverage throughout the country, identified coverage-related challenges to accessing asthma care within states, and found substantial gaps between guidelines-based asthma care and coverage by state Medicaid programs.
Researchers developed a set of items based on a previous literature review and patients’ focus groups and tested it on a wide set of patients with episodic and chronic migraine.
Researchers recently investigated what role exercise plays in migraine prevention and found that although exercise can trigger migraine attacks, regular exercise may have prophylactic effects on migraine frequency.
Patients who use inhaled steroids to control their asthma or other breathing problems may be at a greater risk for developing nontuberculous mycobacterial lung infections.
Patients with chronic obstructive pulmonary disease (COPD) often have a significant disease burden that is particularly associated with the peak incidence of exacerbation events during winter months. A review assessed previous population studies that evaluated the impact of seasonality in COPD, emphasizing the importance of understanding how all factors impact patients and where interventions can be targeted.
A recent study compared the fracture risk between osteoporosis and osteopenia.
Older age, dyspnea, longer duration of illness, comorbidities, and use of oxygen hurt quality of life for those with chronic obstructive pulmonary disease.
Despite there being effective therapies, asthma is commonly poorly controlled. Acknowledging and addressing patient treatment beliefs and perceptual barriers to adherence to asthma medication is necessary for designing adherence interventions for patients.
Myofascial trigger points are prevalent in both migraine and tension-type headaches. However, their role in the pathophysiology of each disorder and to what degree is unclear.
A study says it found a link between bone mineral density and sleep onset latency in an elderly population.
There is an association between an individual’s perceptions of community safety and adverse respiratory health among populations with exposure to high air pollution, according to new research.
A recent study has found that prolonged auras are common and are phenotypically similar to other auras. Based on the observed duration of aura symptoms, the researchers suggest reconsidering the use of the term “prolonged aura."
A study investigating the genetic determinants of fracture risk identified 15 genetic determinants of fracture, which also influenced bone mineral density. Among the clinical risk factors considered, only bone mineral density demonstrated a major causal effect on fracture, while genetic predisposition to lower levels of vitamin D and estimated calcium intake from dairy were not associated with fracture risk, according to the results.
There is an increased need for potential biomarkers that can identify patients with chronic obstructive pulmonary disease (COPD) who will benefit from treatment involving inhaled corticosteroids (ICS). According to a recent study, the 2% threshold for blood eosinophils could accurately predict ICS treatment response in patients with COPD, but the risk of pneumonia was increased.
In 2015, the 20 mg/mL dose of the product was approved in the United States as the first generic version of the drug glatiramer acetate and was a fully substitutable generic that was approved for all indications of the dose.
Patients with asthma with certain genotype combinations demonstrate more intense symptoms when combined with a close proximity to roadways, suggesting that traffic-related air pollution exposure may affect the likelihood of asthma diagnosis and exacerbations.
Twice-yearly treatment with denosumab, a fully human monoclonal antibody, may be associated with increased bone mineral density (BMD) among patients who receive adjuvant aromatase inhibitors (AIs) therapy, according to a recent study.
Telerehabilitation (TR), defined as telecare that involves supervised online exercise sessions for patients with chronic obstructive pulmonary disease (COPD), is beneficial for symptom relief, physical function, and quality of life. A recent study found that specific attention toward the involvement of health professionals in the decision process combined with education and skill training is essential to support the successful implementation of TR.
Ovid Therapeutics Inc., a biopharmaceutical company, recently announced that the phase 2 STARS trial, which tested the efficacy of the investigational drug OV101, achieved its primary endpoint of safety and tolerability for treating Angelman syndrome.
Fragility fractures are a serious complication of type 1 and type 2 diabetes, but many clinicians who treat patients with diabetes are not aware of the increased risk of these fractures.
Early hospital readmissions for patients with asthma and chronic obstructive pulmonary disease (COPD) represent a major economic burden within the healthcare system and recent research found that comorbid chronic rhinitis is significantly associated with 30-day asthma and COPD related readmissions
Researchers evaluating the different methods used to predict the progression of multiple sclerosis (MS) found that human–machine hybrid predictions led to better prognoses than did machine learning algorithms or groups of humans alone.
Patient with chronic migraine were more likely to have aggression, anger, and hostility. Comorbid aggression may help to identify suicidality in migraine patients.
A substantial number of prescribers did not regard nonselective beta blockers as contraindicated, suggesting the need for improvement programs that target the prescribers’ awareness and knowledge.
A new study aimed to assess the prevalence of allergic sensitization, asthma, eczema, and hay fever from infancy to adulthood, finding that patterns of atopic disorders vary throughout childhood.
Viruses, when engineered, may have the potential to alter the course of cancer by driving tumor cells to express novel viral antigens or enhance the production of existing tumor antigens.
Group 2 innate lymphoid cells, a rare form of lymphocyte that defend the body from pathogens, may have immune-regulatory functions in rheumatoid arthritis and play a key role in the development of inflammatory arthritis, according to immunologists at Friedrich-Alexander-Universität Erlangen-Nürnberg.
A recent review evaluated current data on the effects of sex hormones on transient receptor potential channels, which contribute to the sensitization in migraine and chronic pain syndromes.
Researchers recently developed a systematic map of the cell types that make up the mouse nervous system which has the ability to reveal new information about the origin of neurological diseases, and may lead to a detailed map of the human brain.
