
Performance on a manual dexterity test can act as an objective behavior marker that can aid in detecting the prodromal stage of patients with Parkinson disease.
Allison is Associate Editorial Director for The American Journal of Managed Care® (AJMC®) and The Center for Biosimilars®. She joined AJMC® in 2017. She produces and oversees written, video, and podcast content across several disease states and issues surrounding value-based care and health policy.
She has an MPA from New York University. You can connect with Allison on LinkedIn.

Performance on a manual dexterity test can act as an objective behavior marker that can aid in detecting the prodromal stage of patients with Parkinson disease.

A recent study identified the pretransplant characteristics contributing to delayed engraftment (DE) following autologous hematopoietic cell transplantation (AHCT).

With increasing awareness of genetic testing and advancements in precision medicine, more patients are seeking counsel from clinicians about what steps they should take if mutations are found. This requires physicians to become more informed, and a recent article discusses the hypothetical case of an Ashkenazi Jewish woman with breast cancer.

HHS Secretary Alex Azar said his messaging about the Affordable Care Act (ACA) will be simple if the federal 5th Circuit Court of Appeals, in a decision that is expected any day now, sides with the administration in Texas vs Azar in finding the 2010 landmark health law unconstitutional. “Keep calm and carry on,” he said, as he and CMS Administrator Seema Verma released information about 2020 ACA premiums and health plan choices.

A recent study illustrated the benefits of tildrakizumab for patients with psoriasis with comorbid metabolic syndrome.

A meta-analysis suggests that patients with bipolar disorder have a much greater risk of developing Parkinson disease (PD).

The study found that, on average, it took nearly 2 months or longer for patients of color to receive immunomodulatory drugs such as lenalidomide and/or proteasome inhibitors such as bortezomib and carfilzomib. The use of these therapies has more than doubled survival of patients with multiple myeloma within the past decade.

As a result of the study, investigators suggested expanding the indication for tesamorelin (Egrifta) to include people living with HIV who have been diagnosed with nonalcoholic fatty liver disease (NAFLD), a comorbidity in HIV.

Patients with severe psoriasis have an increased risk of dying from liver, esophageal, and pancreatic cancers, and people with psoriasis have an overall increased risk of a variety of other cancers, according to a meta-analysis and review published Wednesday in JAMA Dermatology.

Patients on Medicare with metastatic breast cancer who receive treatment that is discordant with NCCN guidelines bear a greater burden of patient cost responsibility than patients who do receive care according to treatment guidelines.

Declines in global health status and quality of life, physical functioning, fatigue, and pain begin to appear 2 to 3 months before progression of the underlying malignant disease, multiple myeloma researchers said in a new study.

A higher-than-normal body mass index (BMI) at the time of a diagnosis of Parkinson disease (PD) has a protective effect against cognitive decline and the conversion to dementia, a recent study indicated.

In an effort to educate clinicians about the issue of forcing patients in pain to suddenly halt opioid use, HHS released a guide that emphasizes patient-centered care and recommends against a rapid taper or stopping opioids all at once, while a patient living with chronic pain both welcomed the guide and expressed concern.

In a long-awaited move, HHS announced Tuesday plans to reform federal antikickback statutes and overhaul the so-called Stark Law, which was originally intended as a safeguard against financial incentives that would inappropriately influence physicians’ clinical decisions, in an effort to speed the transition to value-based care.

In a long-awaited move, HHS announced Tuesday plans to reform federal antikickback statutes and overhaul the so-called Stark Law, which was originally intended as a safeguard against financial incentives that would inappropriately influence physicians’ clinical decisions, in an effort to speed the transition to value-based care.

JAMA on Tuesday retracted and republished a 2018 study about chronic obstructive pulmonary disease (COPD) after the discovery of a programming error in the statistical analysis. The subsequent complete reanalysis by the authors showed that the intervention that was studied showed harm, rather than benefit, to patients.

Noninvasive transcranial magnetic stimulation (TMS) may help improve cognitive performance in patients with Parkinson disease (PD) and mild cognitive impairment, according to a recent study.

The Government Accountability Office (GAO)’s analysis of Indian Health Service (IHS) data shows that from fiscal years 2013 through 2018, the percentage of patients at federally operated IHS hospitals and health centers who reported having health insurance coverage increased an average of 14 percentage points, from 64% in 2013 to 78% in 2018.

Researchers said the previous results on high sensitivity C-reactive protein and migraine are mixed, and the relationship to insomnia limited; the aim of this study was to evaluate the cross-sectional association between hs-CRP and types of headache, and to see whether the relationship to insomnia could be reproduced.

Governments and health systems can save money in the long term and improve health outcomes by investing earlier in social determinant of health strategies that help people with housing, exercise, mental health, as well as the ability to afford costly prescription drug medication, the report said.

Researchers said Wednesday they created a second-generation chimeric antigen receptor (CAR) T-cell therapy that prevented relapse of lymphoma and leukemia and led to 100% long-term survival in early laboratory studies.

Residents of North Pasadena, Texas, struggling with food insecurity obtained “prescriptions” for healthy food from their clinic providers and boosted their intake of fruits, vegetables, lean protein, beans, and whole grains, in another example of the food as medicine movement that also illustrates some of the challenges with these efforts.

House Speaker Nancy Pelosi unveiled her plan to lower drug prices by giving the government the ability to negotiate prices for up to 250 of the costliest drugs, including insulin; slapping pharmaceutical companies with penalties if they refuse to negotiate; and seeking Medicare rebates from drug makers if they raise prices beyond inflation.

CMS made an “error of law” when it tried to expand a site-neutral payment system, a federal judge ruled.

The Health Care Cost Institute (HCCI) Tuesday released their final Healthy Marketplace Index, which also showed that 69% of markets studied showed an increase in concentration.

The research found that aerobic exercise for 30 to 45 minutes for 3 times a week had an effect similar to that of several conventional Parkinson drugs in patients with mild severity.

As an FDA advisory committee prepares to meet Friday to discuss an application from Aimmune Therapeutics for AR101, its peanut oral immunotherapy (OIT) product, results of a different phase 2 study were released late Thursday indicating that those with allergies to the legume would have to continue treatment in order to avoid reactions.

The Trump administration said Wednesday that the FDA will “prioritize” enforcement of flavored e-cigarette regulations in an effort to get them removed from the market.

The discussion about whether existing inflammatory bowel disease (IBD) or new IBD can worsen after secukinumab therapy is not resolved, the researchers said.

Finding a midlife risk factor for dementia—such as migraine—could allow for earlier detection of at‐risk patients.

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