Cameron Santoro is an associate editor for The American Journal of Managed Care® (AJMC®), AJMC.com, and The Center for Biosimilars®.
Expert Insights on Deuruxolitinib for Alopecia Areata
Arash Mostaghimi, MD, MPA, MPH, assistant professor of dermatology, director of the inpatient dermatology consult service, and codirector of the Complex Medical Dermatology Fellowship at Brigham & Women's Hospital, discusses the recent FDA approval of deuruxolitinib for the treatment of moderate to severe alopecia areata.
Research Explores Novel Insights on Pediatric Hair Loss
Posters presented at the Society for Pediatric Dermatology Annual Meeting shed new light on pediatric hair loss, including the rising prevalence of androgenetic alopecia in children, the potential of artificial intelligence to assess hair loss severity, and the long-term safety of ritlecitinib for treating alopecia areata in adolescents.
Advancements in Asthma Treatment: Next Steps and Insights From Clinical Development of Rilzabrutinib
Leda Mannent, MD, global project head, Immunology and Inflammation, Sanofi, outlines future steps for the clinical development of rilzabrutinib, as well as promising data to advance to phase 3 studies.
Black Women With Obesity, Elevated Leptin Levels at Higher Risk for Breast Cancer
The risk of early-onset breast cancer, particularly luminal A and triple-negative subtypes, was higher in Black women with obesity and high leptin levels compared with White women. This research highlights the urgent need for targeted interventions to address racial disparities in breast cancer outcomes.
Tiara Green Calls for Comprehensive Support for Rare and Chronic Diseases
Health care inequity is costing the United States billions of dollars without providing quality outcomes for patients with rare and chronic diseases, Tiara Green, MSEd, president of Accessia Health, tells The American Journal of Managed Care.
Risks, Benefits of Bilateral Mastectomy for Unilateral Breast Cancer
Despite a significant increase in women with unilateral breast cancer who received a bilateral mastectomy, this study found no survival benefit compared with other treatment options. Although removing the unaffected breast reduces the risk of developing cancer in the other breast, results did not show decreased risk of death from breast cancer.
Exploring Comorbidities, Dupilumab Treatment in Pediatric Alopecia Areata
Two posters presented at the Society for Pediatric Dermatology Annual Meeting explored common health conditions linked to childhood alopecia areata and the effectiveness of dupilumab treatment in children with both alopecia areata and atopic dermatitis.
Diagnosing and Managing Scarring Alopecia in Adolescents
Marissa Joseph, MD, MSc, FRCPC, medical director at Women’s College Hospital in Toronto, Ontario, Canada, highlighted cases from her practice to illustrate the recommended approach to scarring inflammatory scalp dermatosis in adolescents at the Society for Pediatric Dermatology Annual Meeting.
New Study Suggests Alopecia After COVID-19 Vaccine Rare but Possible
A literature review found a link between COVID-19 vaccination and alopecia, with most cases experiencing hair loss within 1 month after the first dose. However, the small sample size and limited data call for further investigation.
Expert Consensus Offers Guidance for Treating Androgenetic Alopecia
An expert consensus by Spanish dermatologists offers treatment recommendations for androgenetic alopecia, the most common cause of hair loss, using a combination of medications and hair transplantation depending on the patient's sex, age, and other factors.
Lower Utilization Seen for Patients With Breast Cancer Using Remote Monitoring With Texts
A remote monitoring app with alerts for doctors did not improve medication adherence in patients with breast cancer, but those receiving tailored text messages on top of monitoring saw reduced high-cost health care use.
BRCA Genes in Breast Cancer: Balancing Risk, Treatment With Breast-Conservation Therapy
Breast-conserving therapy for BRCA1/2 mutation carriers has higher risks of future breast cancers than the general population, but most patients avoid another cancer event, and many remain bilateral mastectomy–free after 20 years.
Nail Changes in Alopecia Areata: Review of Manifestations, Diagnosis, Management Strategies
Results found nail changes in patients with alopecia areata (AA) can occur before, after, or independent of hair loss with the most common nail problems including pitting, ridging, and white spots.
BLU-222 Shows Safety, Tolerability in Combination Therapy for Patients With Breast Cancer
Early data suggest that BLU-222 combined with ribociclib and fulvestrant is safe and tolerable for patients with HR-positive and HER2-negative breast cancer, potentially overcoming resistance to CDK4/6 inhibitors.
A Breathtaking Crisis, Part 2: Climate Change Worsens Asthma for Underserved Communities
Underserved communities, already facing higher asthma prevalence due to social determinants of health, are disproportionately affected by the impact climate change is having on asthma exacerbations. Potential solutions include education for patients and health care providers, climate litigation to establish environmental rights, and policy changes to curb climate change.
Lasers Offer New Options for Hair Loss Treatment in Alopecia Management
Various laser technologies are emerging as a promising treatment for alopecia, showing effectiveness in hair regrowth with minimal adverse events. These treatments target inflammation and stimulate hair follicles to promote hair growth, but more research is necessary to confirm long-term safety and efficacy for some lasers.