Articles by Darius Lakdawalla, PhD

The prices of targeted oncology therapies have grown substantially, but revenues have not. This is due in part to large declines in per-drug patient counts.

Geographic variation in cancer treatment spending reveals that chemotherapy and hospital inpatient care may offer opportunities for savings for practices participating in the Oncology Care Model.

What Do Pharmaceuticals Really Cost in the Long Run?
ByDarius Lakdawalla, PhD,Joanna P. MacEwan, PhD,Robert Dubois, MD, PhD,Kimberly Westrich, MA,Mikel Berdud, PhD,Adrian Towse, MA, MPhil This study found that brand price at launch and generic entry overstates long-run average pharmaceutical costs, with and without accounting for medical cost offsets.

The Cost of Adherence Mismeasurement in Serious Mental Illness: A Claims-Based Analysis
ByJason Shafrin, PhD,Felicia Forma, BSc,Ethan Scherer, PhD,Ainslie Hatch, PhD,Edward Vytlacil, PhD,Darius Lakdawalla, PhD This study demonstrates that common pharmacy claims-based measures underestimate the effect of actual adherence on inpatient costs among patients with serious mental illness.

Reconsidering the Economic Value of Multiple Sclerosis Therapies
ByTiffany Shih, PhD,Craig Wakeford, MA,Dennis Meletiche, PharmD,Jesse Sussell, PhD,Adrienne Chung, PhD,Yanmei Liu, MS,Jin Joo Shim, MS,Darius Lakdawalla, PhD Availability of multiple sclerosis (MS) therapies provides substantial value to the currently healthy (who may contract MS in the future), particularly when treatment is fully covered by insurance.

Medicaid Prior Authorization Policies and Imprisonment Among Patients With Schizophrenia
ByDana Goldman, PhD,John Fastenau, MPH, RPh,Riad Dirani, PhD,Eric Helland, PhD,Geoff Joyce, PhD,Ryan Conrad, PhD,Darius Lakdawalla, PhD This study examined the impact of prior authorization formularies on the likelihood that patients with schizophrenia will be arrested and incarcerated.

Improving Patient-Centered Care in Diabetes With Comparative Effectiveness Research
ByDouglas K. Owens, MD,Wade Aubry, MD,Roy Beck, MD,Joshua Benner, MD,Jan E. Berger, PharmD,Michael E. Chernew, PhD,Felicia Forma, BSc,Dana P. Goldman, PhD,William H. Herman, MD,Rebecca Killion, MA,Darius Lakdawalla, PhD,Anne L Peters, MD 
Darius Lakdawalla, PhD, addresses the value of diabetes patients' adherence in this clip.

Clinical Outcomes Associated With Rates of Sulfonylurea Use Among Physicians
ByKatalin Bognar, PhD,Kelly Fee Bell, PharmD, MS Phr,Darius Lakdawalla, PhD,Anshu Shrestha, PhD,Julia Thornton Snider, PhD,Nina Thomas, MPH,Dana Goldman, PhD 
Comparative Effectiveness Research and Formulary Placement: The Case of Diabetes
ByMichael E. Chernew, PhD,Rick McKellar, BS,Wade Aubry, MD,Roy Beck, MD, PhD,Joshua Benner, PharmD, ScD,Jan E. Berger, MD, MJ,A. Mark Fendrick, MD,Felicia Forma, BSc,Dana Goldman, PhD,Anne Peters, MD,Rebecca Killion, MA,Darius Lakdawalla, PhD,Douglas K. Owens, MD,Joe Stahl, MA 
Comparative Effectiveness Research and Formulary Placement: The Case of Diabetes
ByMichael E. Chernew, PhD,Rick McKellar, BS,Wade Aubry, MD,Roy Beck, MD, PhD,Joshua Benner, PharmD, ScD,Jan E. Berger, MD, MJ,A. Mark Fendrick, MD,Felicia Forma, BSc,Dana Goldman, PhD,Anne Peters, MD,Rebecca Killion, MA,Darius Lakdawalla, PhD,Douglas K. Owens, MD,Joe Stahl, MA Formularies of the future should use evidence-produced CER to better target, not limit, diabetes care.