Gianna Melillo

Study results published in PLoS One strongly suggest machine learning can be an effective approach to identify patients who should receive a diagnostic biochemical test to screen for acute hepatic porphyria.

Anzueto, a professor of medicine at the University of Texas Health in San Antonio and clinician practicing pulmonary and clinical care, also serves as a member of the GOLD Science Committee.

The intersection of climate change and negative impacts on health were brought into sharp focus this week with executive orders from President Biden, a move by General Motors (GM) to stop making some gasoline-powered cars, and top global cardiology organizations calling for urgent action on air pollution.

Results of a case-control study show metformin use may protect against the development of age-related macular degeneration (AMD) in adults 55 years and older, and the association is dose-dependent, with the greatest benefit at low to moderate doses.

A prospective cohort study found that diabetes and insulin resistance were the strongest risk factors for premature onset of coronary heart disease (CHD) among American women. Results were published in JAMA Cardiology.

Treatment with erenumab led to improvements in pain, medication use, and quality of life in onabotulinumtoxinA-resistant patients with chronic migraine, according to study results published in The Journal of Headache and Pain.

Metabolic surgery is more effective than conventional medical therapy in the long-term control of type 2 diabetes (T2D), according to results of a 10-year follow-up study of a randomized controlled trial published in The Lancet.

During the coronavirus disease 2019 pandemic in France, researchers found a 7-fold increase in the number of alcohol-based hand sanitizer eye exposures among children.

In a review published in Therapeutics and Clinical Risk Management, researchers outlined the current understanding of the transthyretin amyloidosis (ATTR) disease process, diagnostic and surveillance approaches, treatment modalities, and potential future directions.

Meilan King Han, MD, a professor of internal medicine at the University of Michigan, discusses how her practice has altered patient care to adapt to the ongoing pandemic and challenges patients with chronic obstructive pulmonary disease (COPD) and providers face when dealing with a highly contagious airborne respiratory virus.

Lower socioeconomic status (SES) and barriers related to the perceived need for exercise rehabilitation were associated with decreased referral to rehabilitation among patients with pulmonary arterial hypertension (PAH).

Treatment with interleukin-6 receptor antagonists tocilizumab and sarilumab resulted in improved outcomes, including survival, among critically ill patients with coronavirus disease 2019 (COVID-19) receiving organ support in intensive care.

Results of a vignette-based survey study indicate patients with diabetes require greater health benefits to adopt more intrusive remote digital monitoring (RDM), food monitoring, and real-time feedback by a health care professional.

As Rochelle Walensky, MD, MPH, prepares to assume the role of CDC director on January 20, the infectious disease specialist faces a myriad of challenges wrought by the ongoing coronavirus disease 2019 (COVID-19) pandemic.

Results from a prospective observational study showed aqueous transforming growth factor beta and autotaxin exhibited high diagnostic performance in detecting glaucoma subtypes and could serve as promising biomarkers for glaucoma.

Compared with triptan nonresponders, patients with migraine who report a response to at least 1 triptan have a higher likelihood of responding to treatment with erenumab, according to real-world data published in The Journal of Headache and Pain.

Results of a phase 2 trial showed that an activin type II receptor blockade, achieved via bimagrumab, led to significant loss of fat mass, gain in lean mass, and metabolic improvements among patients with type 2 diabetes (T2D) and overweight or obesity.

Swedish patients with type 2 diabetes and obesity who underwent gastric bypass surgery exhibited a reduced risk of developing new diabetic retinopathy, compared with those who did not undergo surgery.

A flow cytometric score developed in 2012, which uses 4 parameters to distinguish low-grade myelodysplastic syndromes (MDS) from nonclonal cytopenias, is simple and practical for screening patients with MDS, according to research published in the American Journal of Translational Research.

New research underscores the substantial economic burden associated with early discontinuation of guideline-recommended hypomethylating agent (HMA) therapy among patients with refractory anemia with excess blasts, a diagnosis that substantially overlaps with higher-risk myelodysplastic syndrome (MDS).

Mepolizumab and benralizumab are both potent targets of the interlukin-5 pathway with the ability to significantly reduce eosinophil counts, according to new research published in Allergy, Asthma & Clinical Immunology.

The US Surgeon General, Vice Admiral Jerome Adams, MD, and other officials urged for greater uptake of FDA-approved treatments for coronavirus disease 2019 (COVID-19) in an effort to slow the surge of cases requiring hospitalization. However, logistic, monetary, and efficacy concerns may have drastically limited the amount of biologic treatments actually administered to patients.

Home confinement during the coronavirus disease 2019 pandemic was associated with a significant myopic shift among Chinese children aged 6 to 8, according to new research published in JAMA Ophthalmology.

Non-Hispanic Black individuals with type 1 diabetes and coronavirus disease 2019 infections may be more likely to be hospitalized for diabetic ketoacidosis (DKA) compared with non-Hispanic White patients.

Starting in 2 weeks, allocation of coronavirus disease 2019 (COVID-19) vaccines will be based on the percentage of doses each state has successfully administered thus far and the number of residents aged 65 or over, according to HHS.

Erenumab treatment has been associated with reductions in migraine frequency and improvements in health-related quality of life that were maintained for at least 5 years, according to the results of an open-label treatment phase of a recent study.

Study results, published in JAMA Ophthalmology, showed the Home Acuity Test can be used to measure visual acuity by telephone for a wide range of outpatients with diverse conditions under the care of an ophthalmologist.

A new American Diabetes Association (ADA) survey highlights how the coronavirus disease 2019 (COVID-19) pandemic took a toll on the population with diabetes, which is one of the most prevalent preexisting conditions in America.

Data on patients with migraine who stopped erenumab treatment show that over half of patients had an early disease worsening while the remaining patients maintained their responder status during weeks 1 through 4 post treatment.

Researchers conducting a large epigenome-wide association study identified several methylation sites associated with hereditary transthyretin amyloidosis (hATTR), a rare, life-threatening disorder caused by amyloidogenic coding mutations in the TTR gene.