Hayden E. Klein

New findings show that VX-880, a stem cell-derived islet cell therapy, can restore endogenous insulin secretion and improve glycemic control in people living with type 1 diabetes (T1D).

New estimates predict that type 2 diabetes prevalence will more than double in the next 30 years, from 529 million people in 2021 to at least 1.3 billion in 2050.

Yesterday’s FDA approvals of a new indication for empagliflozin and combination empagliflozin with metformin hydrochloride for pediatric type 2 diabetes (T2D) provide a new class of oral drugs to treat the condition in children.

Improving access to diabetes technology so that everyone can benefit is a top priority, said David Maahs, MD, PhD, professor of pediatrics at Stanford University and division chief of pediatric endocrinology at Lucile Packard Children’s Hospital.

Biosimilars are starting to make a significant impact in overall drug spending, which is what they are designed to do, said Scott Soefje, PharmD, director of pharmacy cancer care at Mayo Clinic.

Preliminary data suggest the number of meningococcal disease cases among individuals with HIV doubled in 2022, while vaccination rates for the disease remain low.

An evaluation of a same-day HIV pre-exposure prophylaxis (PrEP) program in Jackson, Mississippi, showed that most individuals given a same-day prescription either never started PrEP or stopped use within 3 months.

David Maahs, MD, PhD, professor of pediatrics at Stanford University and division chief of pediatric endocrinology at Lucile Packard Children’s Hospital, talks about the Timely Interventions for Diabetes Excellence dashboard, increases in continuous glucose monitoring, and more.

Among a small cohort of healthy Korean male volunteers, evogliptin combined with empagliflozin or dapagliflozin had no significant effects on the pharmacokinetics (PK) of each drug.

If payers can agree on consensus criteria to improve care quality or costs, that will help physicians remember and try to be compliant, said Samyukta Mullangi, MD, MBA, incoming medical director at Thyme Care.

The pilot 4T study showed consistent hemoglobin A1C improvement in all children with type 1 diabetes (T1D) after 1 year, underscoring the importance of early continuous glucose monitoring (CGM) following diagnosis, explained David Maahs, MD, PhD, professor of pediatrics at Stanford University and division chief of pediatric endocrinology at Lucile Packard Children’s Hospital.

The Respiratory Infection Intensity and Impact Questionnaire (RiiQ) Symptoms Scale demonstrated logical patterns of upper and lower respiratory symptoms among participants.

In a review of adults with type 1 diabetes (T1D), having a body mass index (BMI) <18.5 kg/m2 increased the risk of all-cause mortality by 3.4 times compared with normal BMI.

Among women on Medicaid, the prevalence of Kaposi sarcoma—a cancer commonly associated with HIV—was 82 times higher in women with HIV compared with women without HIV.

"It's really important that oncologists are on level footing along with the rest of their medical peers," said Samyukta Mullangi, MD, MBA, incoming medical director at Thyme Care.

According to new estimates, the US government spent between $143 million and $314 million in 2022 inflation-adjusted dollars funding the development of tenofovir disoproxil fumarate-emtricitabine. The previous estimate was around $50 million.

Amal Agarwal, DO, MBA, chief clinical officer at Monogram Health, explains the importance of value-based agreements in dialysis care, and the issue of dialysis prevalence among low-income and marginalized communities.

Individuals with type 1 diabetes (T1D) had brain atrophy patterns equivalent to a brain age about 6 years older than their actual age.

The study also showed that the measurement of HbA1c—which serves as an indicator of clinical assessment—sharply drops in the late teenage years among individuals with type 1 diabetes (T1D).

In a case report, dupilumab and prednisone were among the treatments for atopic dermatitis (AD) used to relieve a patient of her delayed generalized hypersensitivity reaction to the mRNA COVID-19 vaccine.

A review of 24 meta-analyses supported the need for additional monitoring of patients with diabetes and COVID-19, especially if they have comorbidities associated with diabetes.

A CDC report emphasized the need for increased investments, innovation, and focus on equity in order to end the HIV epidemic.

At the Pharmacy Quality Alliance (PQA) 2023 Annual Meeting, the strategy advancement lead at Humana talked more about Humana’s health equity strategy and areas that pharmacy benefit managers (PBMs) and health plans can influence.

Telehealth provides more flexibility for patients with gastrointestinal issues to better fit their care into their lives and around symptoms they may be experiencing, said Sam Holliday, co-founder and CEO of Oshi Health.

Having at least 2 episodes of severe hypoglycemia that required hospitalization was found to be a major predictor for time to death in individuals with type 1 diabetes (T1D).

Between 2010 and 2020, pediatric antiretroviral therapy (ART) coverage tripled, but still consistently lagged behind adult ART coverage.

Pharmacists at the Pharmacy Quality Alliance (PQA) 2023 Annual Meeting discussed the role of data collection and analysis in the movement toward health equity.

David Maahs, MD, PhD, professor of pediatrics at Stanford University and division chief of pediatric endocrinology at Lucile Packard Children’s Hospital, highlights key points from his review on pediatric diabetes technology and therapy.