Rose McNulty

This new study aimed to identify metabolic differences in endothelial cells in pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension (PH) to aid in the development of novel therapeutic approaches.

An update to the ERNEST study found a survival benefit in ruxolitinib for the treatment of myelofibrosis in both the first and second line vs hydroxyurea.

Contrary to research done on adults, a recent study found that children may be highly sensitive to light exposure of any intensity before bedtime.

Metastatic renal cell carcinoma (mRCC) has seen increased treatment options in recent years, including immunotherapy (IO) combinations paired with tyrosine kinase inhibitors (TKI). A meta-analysis of phase 3 trials aimed to compare and rank available first-line treatments.

A recent analysis found a strong negative correlation between plasma THC levels and intraocular pressure in healthy adults after smoking cannabis.

Nasal surgical intervention led patients with obstructive sleep apnea (OSA) who historically were nonadherent to continuous positive airway pressure (CPAP) treatment to become adherent and experience improvements in objective and subjective severity measures.

Idiopathic pulmonary arterial hypertension and pulmonary hypertension due to chronic lung disease can be difficult to differentiate, but new research suggests descriptions of lung parenchyma in routine CT scans may prove useful.

Nocturnal road traffic noise was strongly linked to a range of insomnia symptoms, highlighting the potential impact of noise pollution on public health in large populations.

A poster presentation from the 2022 American Society of Clinical Oncology (ASCO) Gastrointestinal Cancers Symposium suggests more research is needed to confirm the optimal treatment algorithms for patients with hepatocellular carcinoma.

A patient with medication-induced severe acute generalized exanthematous pustulosis responded to treatment with secukinumab after unsuccessful courses of topical and systemic steroids.

Patients in upper quartiles of the sleep breathing impairment index, a novel gauge of obstructive sleep apnea (OSA) severity, had higher 10-year Framingham cardiovascular risk than patients whose symptoms were classified as less severe.

A recent study suggests a conceptual deep neural network–based surgical guidance platform is precise and has potential as a valuable tool during phacoemulsification procedures.

A recent study found an association between biological rhythms affecting sleep late in pregnancy and postpartum and depressive or anxiety symptoms.

One of the long-term effects of COVID-19 may be small fiber neuropathy in the ocular surface causing similar symptoms to dry eye disease and diabetic neuropathy, a recent study found.

The severity of excessive daytime sleepiness correlated with the prevalence of Parkinsonian-like symptoms in adults aged 50 to 64, but further research is needed to determine the mechanisms behind the findings.

Recent research suggests targeted memory reactivation might help with facial recognition and name recall, but quality and quantity of sleep may be important factors in effectiveness.

An abstract presented at the 63rd American Society of Hematology (ASH) Annual Meeting and Exposition assessed real-world data on patients with multiple myeloma to provide insight into longitudinal testing patterns and rates of sustained minimal residual disease (MRD) negativity.

Recent findings suggest that with more research, anomaly detection may be an option for general retinal disease screening and identification of novel presentations of common retinal diseases.

An abstract presented at the 63rd American Society of Hematology Meeting & Exposition found that the regimen was effective and that MRD could potentially be used as a biomarker to inform treatment duration.

Chronic cough can have a significant impact on patient quality of life, and recognizing it as an individual condition may help optimize its treatment.

A survey of health care workers in New York City during the COVID-19 pandemic’s peak identified associations between poor sleep and anxiety, acute stress, and depressive symptoms.

A large real-world analysis assessed age-related changes in commonly used visual field reliability indices and the potential mechanisms behind the trends.

A Danish study observed emergency department (ED) health care providers and identified 5 factors that could play into patient involvement in medication discussions, particularly in older patients with polypharmacy.

One-year outcomes varied among patients with differing neovascular glaucoma etiologies, but many achieved meaningful vision after surgical treatment that included glaucoma drainage devices.

The respiratory complications of spinal muscular atrophy are well-researched, but a new study provides insight into nonrespiratory complications that may be just as crucial.

Researchers found 18 novel and 21 known variants of SMPD1 with disease-causing potential, providing data that may be helpful in prenatal diagnosis of acid sphingomyelinase deficiency in India.

Recent studies show that glucagon-like peptide-1 receptor agonists have anti-inflammatory effects in human and rodent pathological models, making them a potential therapeutic strategy for treating pulmonary arterial hypertension after COVID-19 infection.

Patients with spinal muscular atrophy often present with severe scoliosis but face an elevated risk of complications from corrective surgery.

A case series of corrective surgeries in children with severe scoliosis due to spinal muscular atrophy (SMA) type 1 showed a positive success rate, but with significant postoperative complications.

Findings from the single-arm, open-label ASCEND-Peds trial suggest olipudase alfa is well-tolerated and may lead to clinically meaningful improvements in patients with acid sphingomyelinase deficiency (ASMD) who do not have neurovisceral manifestations.