Alopecia

Latest News

The authors recommend incorporating more SoC-specific imagery and case discussions into dermatology curricula, along with a stronger emphasis on biopsy in unclear cases. | Image Credit: Prostock-studio - stock.adobe.com
High Rates of Misdiagnosis in Hair, Scalp Disorders Among Patients With Skin of Color

August 13th 2025

Hair and scalp disorders in patients with skin of color are frequently misdiagnosed, often due to educational gaps and premature diagnosis, with scalp biopsy proving more reliable than trichoscopy for accurate diagnosis.

The new data are from one of 2 pivotal phase 3 trials designed to study the safety and efficacy of upadacitinib in adults and adolescents with severe AA. | Image Credit: Yurii Kibalnik - stock.adobe.com
Upadacitinib Shows Strong Efficacy in Phase 3 Alopecia Areata Trial

August 7th 2025

Though it would seem surprising for alopecia therapies with overlapping targets to lead to different patient outcomes, the authors said the evidence suggests the strategy can work. | Image credit: Nadya Kolobova - stock.adobe.com
New Strategies and Combinations Could Help Address AA Relapse

August 1st 2025

The new report evaluated how alopecia areata affects mental health across cultural and national borders. | Image credit: melita - stock.adobe.com
Links Between Alopecia and Mental Health Vary by Country

July 21st 2025

The JAKis evaluated were effective in a dose-dependent manner, the study found. | Image Credit: Victoria - stock.adobe.com
Analysis Highlights Comparative Efficacy of Alopecia Areata Drugs

July 18th 2025

More News

Medical technology concept. | Image Credit: Nuttapong punna - stock.adobe.com
July 9th 2024

Nail Changes in Alopecia Areata: Review of Manifestations, Diagnosis, Management Strategies

Cameron Santoro
Results found nail changes in patients with alopecia areata (AA) can occur before, after, or independent of hair loss with the most common nail problems including pitting, ridging, and white spots.
Young black woman with hair concern| Image Credit: Prostock-studio-stock.adobe.com
July 1st 2024

Survey Shows Suboptimal Comfort in Treating Hair Among Patients With SOC

AJMC Contributor
In addition to ensuring residency programs provide educational and practical opportunities for addressing skin of color (SOC) hair-related concerns, prioritizing having residents of diverse backgrounds can help close knowledge and comfort gaps, suggest researchers.
Dermatologist conducts laser therapy. | Image Credit: Tetiana - stock.adobe.com
June 29th 2024

Lasers Offer New Options for Hair Loss Treatment in Alopecia Management

Cameron Santoro
Various laser technologies are emerging as a promising treatment for alopecia, showing effectiveness in hair regrowth with minimal adverse events. These treatments target inflammation and stimulate hair follicles to promote hair growth, but more research is necessary to confirm long-term safety and efficacy for some lasers.
Dermatologist examines hair breakage | Image Credit: shidlovski - stock.adobe.com
June 26th 2024

Alopecia Areata Hair Breakage Linked to Cysteine Deficiency

Cameron Santoro
The review explores the potential link between alopecia areata (AA) and cysteine metabolism. Research suggests insufficient cysteine levels or disruptions in its processing could contribute to AA development. Further studies are needed to confirm these connections and explore potential therapeutic strategies targeting cysteine metabolism for AA treatment.
Trichologist examines head of patient | Image Credit: Siniehina - stock.adobe.com
June 25th 2024

Exploring the Potential of Thyroid Receptor β for Treating Androgenetic Alopecia

Cameron Santoro
This scientific review examines the potential of targeting the thyroid receptor β (TRβ) for developing new drugs to treat androgenetic alopecia, with the authors discussing various mechanisms by which TRβ might work and analyze promising drug candidates.
Trichoscopy | Image Credit: familylifestyle - stock.adobe.com
June 19th 2024

Unveiling Treatment Options for Alopecia Areata

Cameron Santoro
In a European expert consensus statement, researchers discover the exciting breakthroughs for patients with alopecia areata (AA). This article explores the unlocked potential of combination therapies and targeted biologics to regrow hair and transform lives.
Alopecia medicine | Image Credit: Victoria - stock.adobe.com
June 18th 2024

Ritlecitinib Effective For Patients With Alopecia Areata, Improves Hair Regrowth

Maddi Hebebrand
A poster from the 2024 Revolutionizing Alopecia Areata, Vitiligo, and Eczema (RAVE) conference held in Chicago, Illinois presented results of a clinical trial for patients with alopecia areata (AA). The trial used rilecitinib and showed promising results in patients with AA after most patients achieved significant hair regrowth following 15 months of treatment.
AA Medication | Image Credit/ KenamiRyoko - stock.adobe.com
June 13th 2024

Benefits of JAK Inhibitors Compared With Existing Therapies for AA Treatment

Cameron Santoro
Different Janus kinase (JAK) inhibitors underwent an evaluation for severe alopecia areata (AA) and found deuruxolitinib higher doses (12 mg) and baricitinib (4 mg) showed promise in hair regrowth improvement, but further research must be done to confirm these results while more long-term effects are explored.
Alopecia | Image Credit: Andrey - stock.adobe.com
June 10th 2024

Scalp Cooling Therapy Effective in Reducing Chemotherapy-Induced Alopecia

Cameron Santoro
Scalp-cooling therapy (SCT) is a treatment that may help reduce hair loss in women with breast cancer who are experiencing chemotherapy-induced alopecia (CIA). A study found that many women who used SCT were satisfied with the results, but the treatment is expensive, making it necessary for more advocacy by health care professionals to make SCT accessible.
Woman holding brush full of hair | Image Credit: anaumenko - stock.adobe.com
May 31st 2024

History of Oral Contraceptive Use, Gene Variant May Increase Risk of FFA

Cameron Santoro
A case controlled study suggests a gene variant may offer some protection from frontal fibrosing alopecia (FFA), but only if there is no prior history of oral contraceptive pill use, which appears to increase the risk for carriers of this variant.
Male pattern baldness | Image Credit: Oksana - stock.adobe.com
May 30th 2024

Patients With AGA Treated With PRP Display Hair Regrowth, Potential Microbiome Rebalance

Cameron Santoro
Platelet-rich plasma (PRP) treatment increased hair regrowth in patients with androgenetic alopecia (AGA) and may help rebalance the scalp microbiome, although the link between the microbiome changes and hair growth needs future investigations.
Receding hairline | Image Credit: Bongkochrut - stock.adobe.com
May 28th 2024

Primary Cicatricial Alopecia Connected to Increased Risk of Endocrine, Metabolic Diseases

Cameron Santoro
A study using a large Korean health database found that people with a rare hair loss disorder called primary cicatricial alopecia were more likely to also have additional health problems like diabetes and high blood pressure compared with people who had other hair loss conditions or no hair loss at all.
Microneedling hair loss treatment | Image Credit: Dharma - stock.adobe.com
May 14th 2024

Scalp Repair Serum Microneedling: Fewer Treatments, More Hair Regrowth for AGA

Cameron Santoro
A study found scalp repair serum microneedle combined therapy with medication to improve hair growth outcomes for patients with moderate to severe androgenetic alopecia (AGA) and reduce the number of microneedling sessions necessary.
Illustration of patient with AA at doctor | Image Credit: Rudzhan - stock.adobe.com
May 13th 2024

Alopecia Areata Risk Associated With Atopy, Allergies

Cameron Santoro
A genetic study suggests people with allergies and eczema are more likely to develop alopecia areata, an autoimmune disease that causes hair loss. Researchers believe this link may be due to similar immune system responses.
Mature woman with alopecia. | Image Credit: highwaystarz - stock.adobe.com
May 7th 2024

AA Unlikely to Cause Anxiety, Depression but May Be Affected by Mental Illness

Cameron Santoro
A Mendelian randomization study using genetic analysis found that alopecia areata (AA) increases the risk of anxiety and depression, but not the other way around, providing unique evidence for a causal link while adding to existing evidence.
Thin hair loss on non-White man | Image Credit: Alessandro Grandini - stock.adobe.com
April 25th 2024

Insurance Coverage Limits JAKi Therapy Access for Patients With AA, Especially Non-White Populations

Cameron Santoro
A survey study showed major barriers to Janus kinase inhibitor (JAKi) therapy for patients with alopecia areata, especially for non-White patients who face higher rates of being uninsured and struggle more to afford the treatment.
Woman with hair loss | Image Credit: Creative Cat Studio - stock.adobe.com
April 17th 2024

Severe AA Impairs Quality of Life, Study Calls for Holistic Management Strategies

Cameron Santoro
A survey study found a strong association between severe alopecia areata (AA) and significant impairments in quality of life and mental wellbeing, highlighting the need for comprehensive treatment addressing both physical and emotional aspects of the disease.
Physician diagnoses hair loss, alopecia | Image Credit: buravleva_stock - stock.adobe.com
April 14th 2024

AA May Increase Risk of Hypothyroidism, AG Needs Further Investigation

Cameron Santoro
Potential links between alopecia areata (AA) and hypothyroidism were observed among the study but the connection between androgenetic alopecia (AG) and hypothyroidism needs further investigation.
Man with hair loss measuring regrowth | Image Credit: Pixel-Shot - stock.adobe.com
April 10th 2024

Laser-Assisted Drug Delivery Is Effective in Alopecia but Lacks Comparison With Existing Treatments

Cameron Santoro
Studies show that laser-assisted drug delivery (LADD) improves hair growth in patients with alopecia. However, researchers are still looking at the best ways to compare LADD's effectiveness against other methods like microneedling.
Male pattern baldness. | Image Credit: boyloso - stock.adobe.com
April 8th 2024

Treatment Targeting CXCL12 Protein Offers Hope for Patients With AGA, AA

Cameron Santoro
Antibodies targeting the CXCL12 protein show potential to promote hair growth in conditions like androgenic alopecia (AGA) and alopecia areata (AA), offering hope for new treatment options.
Doctor examines child scalp. | Image Credit: Nadzeya - stock.adobe.com
April 4th 2024

Combination Therapies Optimize Hair Regrowth in Pediatric Patients With AA

Cameron Santoro
Corticosteroids are the most common treatment for pediatric patients with alopecia areata (AA), but promising newer options like JAK inhibitors are emerging. This review highlights the importance of personalized treatment plans and maximizing response through combination therapies.
Dermatologist checks woman's scalp. | Image Credit: Andrey Popov - stock.adobe.com
March 29th 2024

Light Therapy Clothing Shows Potential for Mild Psoriasis, PMLE, AA Treatment

Cameron Santoro
Red and near-infrared–emitting fabric clothing may improve symptoms of mild psoriasis, polymorphous light eruption (PMLE), and alopecia areata (AA), but further research with larger groups is needed due to limitations in the pilot study design.
Woman worried about hair loss | Image Credit: Prostock-studio - stock.adobe.com
March 27th 2024

Alopecia Areata Impacts Patient Perception, Quality of Life

Cameron Santoro
Patients with alopecia areata (AA) often perceive their hair loss as more severe than dermatologists do, leading to increased emotional and social problems. This study highlights the importance of understanding patient perception for better treatment and improved quality of life.
Before and after hair regrowth, rear view of male head | Image Credit: Sebastian - stock.adobe.com
March 20th 2024

Tofacitinib Effective for AA, Earlier Intervention Improves Outcomes

Cameron Santoro
Research suggests tofacitinib effectively treats alopecia areata (AA), particularly when used early for severe cases. This offers promising evidence for doctors to consider when making treatment plans for patients.
Woman experiences hair loss | Image Credit: Siam - stock.adobe.com
March 14th 2024

Deuruxolitinib Demonstrates Efficacy, Tolerability in Patients With Moderate to Severe AA

Cameron Santoro
Posters suggest deuruxolitinib, a medication targeting specific cellular pathways, effectively promotes hair regrowth in patients with moderate to severe alopecia areata (AA) and results in minimal adverse events.
Alopecia surrounded by medication | Image Credit: greenapple78 - stock.adobe.com
March 13th 2024

Review Finds JAK Inhibitors More Effective for Moderate to Severe AA Compared With Established Therapies

Cameron Santoro
Baricitinib and other oral JAK inhibitors show promise as effective treatments for moderate-to-severe alopecia areata (AA), with fewer adverse effects compared with traditional options.
Dermatologist checks patient's scalp, wearing surgical masks | Image Credit: Andrey Popov - stock.adobe.com
March 9th 2024

Study Finds No Link Between COVID-19 Vaccine, Alopecia Areata

Cameron Santoro
A study in San Bernardino County found no increased risks of alopecia areata (AA) after the COVID-19 vaccination but suggests further research into potential geographic and gender-based factors.
Hair loss in brush and medicine on table | Image Credit: Viktoriia M - stock.adobe.com
March 5th 2024

Baricitinib Shows Effectiveness, Safety for Severe AA With Room for Further Exploration

Cameron Santoro
A study found baricitinib to be safe and effective for treating severe alopecia areata (AA) but expressed the need for more long-term trials to support these findings.
Woman with hair loss | Image Credit: New Africa - stock.adobe.com
February 29th 2024

Experts Measure AA Severity With Key Factors, Reach Consensus on Treatment Decisions

Cameron Santoro
An expert survey using the eDelphi method pinpointed disease duration, treatment response, and mental health as crucial factors in a new multidimensional tool known as Alopecia Areata Severity and Morbidity Index (ASAMI), underlining the importance of personalized treatments for future research incorporating patient perspectives.
Woman removing wig | Image Credit: Seventyfour - stock.adobe.com
February 23rd 2024

Gender Differences, Disease Severity, Income Disparities Drive Financial Burden in AA

Cameron Santoro
Women with alopecia areata (AA), especially those with severe symptoms and lower income, face significant financial burden managing the condition.
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