Comprehensive Genomic Profiling

The AJMC® Comprehensive Genomic Profiling compendium is a comprehensive resource for clinical news and expert insights for the next-generation sequencing approach to assess genes for the purpose of therapy guidance.

WGS Feasible, Valuable in Metastatic Cancer Management

July 19th 2022, 2:49pm

Article

As the number of known cancer targets and precision therapies increases, implementing whole-genome sequencing (WGS) into regular clinical practice may benefit patients with metastatic cancer.

Survey Provides Insight Into Patient Experiences Receiving Comprehensive Tumor Genomic Profiling Results

July 16th 2022, 11:30am

Article

While comprehensive genetic profiling has the potential to change the course of certain patients’ cancers, a recent survey found that patients often have difficulty understanding results and their implications.

Method of Tissue Acquisition May Determine Success of Gene Sequencing in Lung Cancer

July 7th 2022, 5:35pm

Article

Successful comprehensive genomic profiling of tissue samples among patients with lung cancer was more likely to occur when samples were extracted via resections vs fluid cytology, biopsy, or fine-needle aspirations.

FOENIX Update: A New Era in Cholangiocarcinoma Precision Medicine

July 1st 2022, 12:00pm

Article

Patients with iCCA, particularly those whose disease progresses following first-line chemotherapy, have limited overall treatment options. Data presented at the 2022 American Society of Clinical Oncology (ASCO) Annual Meeting show that patients may soon have a new agent to fight this rare cancer in futibatinib (Taiho Oncology), an FGFR inhibitor.

Dr Elli Papaemmanuil Discusses Molecular Profiling of MDS, Use of Precision Medicine

June 30th 2022, 7:40pm

Video

Elli Papaemmanuil, PhD, assistant professor in computational oncology, Memorial Sloan Kettering Cancer Center, discussed current knowledge on the molecular profile of myelodysplastic syndromes (MDS) and potential use of precision medicine.

Lack of CGP Testing May Result in Missed Therapy Options in NSCLC

June 28th 2022, 8:01pm

Article

A real-world analysis found that comprehensive genomic profiling (CGP) in patients with non–small cell lung cancer (NSCLC) increases their therapy options patients and CGP testing needs to be utilized more.

Dr Hatem Soliman Explains How the DNA Damage Repair Pathway Affects Cancer Progression

June 22nd 2022, 8:09pm

Video

It is important that we learn how to exploit DNA damage repair deficiencies to treat cancer help patients in control their disease. explained Hatem Soliman, MD, medical director, Clinical Trials Office, Moffitt Cancer Center.

Dr Patricia Deverka Discusses Potential Collaborations for Real-world MCED Data Collection

June 18th 2022, 7:30pm

Video

There needs to be an emphasis on how to reduce the cost and burden of real-world evidence studies, said Patricia Deverka, MD, MS, senior researcher and deputy director at the Center for Translational and Policy Research and Precision Medicine, University of California San Francisco.

ESC Genetic Testing Recommendations Address Sudden Cardiac Death Risk in Athletes

June 17th 2022, 6:45pm

Article

Recommendations discuss appropriate use and diagnostic, prognostic, and therapeutic implications of cardiac genetic testing, including guidance on impact of exercise.

AACR Posters Demonstrate CGP for Biomarker Detection and Multiomics Profiling

June 11th 2022, 7:20pm

Article

Posters from the American Association of Cancer Research (AACR) Annual Meeting demonstrated the use of genomic profiling and sequencing can detect immunotherapy biomarkers and predict clinical outcomes in patients with cancer.