Diabetes

The AJMC® Diabetes compendium is a comprehensive resource for clinical news and expert insights for the chronic condition.

Latest News

AJMC
Trends in Insulin Out-of-Pocket Costs and Use Disparities, 2008-2021

July 31st 2025

Given trends in cost and use, insulin out-of-pocket cost reduction policies would be more efficient if they targeted members in high-deductible health plans with savings options and low-income patients.

PFAS | Image credit: Vodkaz - stock.adobe.com
PFAS Exposure Linked to Increased Risk of Type 2 Diabetes, Study Finds

July 29th 2025

Diabetes monitoring | Image credit: abidika - stock.adobe.com
SGLT2i-Induced Erythrocytosis Not Linked to Clots in Type 2 Diabetes

July 21st 2025

MRI head brain scan - DedMityay - stock.adobe.com
Semaglutide, Tirzepatide Cut Dementia, Stroke Risk in Type 2 Diabetes

July 18th 2025

Doctor examines eye anatomy model using magnifying glass | Image credit: Viktor - stock.adobe.com
Clinical Data Predicts Risk of Progression to Proliferative Diabetic Retinopathy

July 15th 2025

Advancing Care in Type 2 Diabetes and Obesity: A Coordinated, Guideline-Driven Approach

Understand how recent advances in GLP-1 receptor agonists and other therapies are transforming the treatment of type 2 diabetes and obesity through a shift of reactive to proactive care that addresses root causes of cardiometabolic disease.

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July 31st 2025

The Economics of Transthyretin-Mediated Amyloidosis: Balancing Equity and Access in Resource Allocation

1 Credit / Cardiology, Neurology
July 31st 2025

Advancing Immunotherapy in Endometrial Cancer: A Managed Care Perspective on Personalized Care

1.5 Credits / Gynecologic Cancer, Health Equity, Diversity & Inclusion, Oncology, Women's Health

More News

Metformin | Image credit: Sherry Young – stock.adobe.com
December 12th 2023

Metformin Does Not Improve Neonatal Outcomes for Pregnant Patients With Diabetes

Hayden E. Klein
Adding metformin to the insulin regimen for pregnant patients with preexisting type 2 diabetes (T2D) or gestational diabetes diagnosed early in pregnancy did not reduce the risk of neonatal adverse outcomes.
AJMC
December 12th 2023

Treatment Modification After Initiating Second-Line Medication for Type 2 Diabetes

David T. Liss, PhD Manisha Cherupally, MS Matthew J. O’Brien, MD, MSc Raymond H. Kang, MA Cassandra Aikman, MPH Amisha Wallia, MD, MS Andrew J. Cooper, MSc Eleena Koep, MS Emily D. Parker, PhD, MPH Ronald T. Ackermann, MD, MPH
Among adults with type 2 diabetes who started noninsulin second-line therapy, most modified treatment within 1 year. Discontinuation was by far the most common modification.
Woman having telemedicine visit on tablet | Image credit: rh2010 – stock.adobe.com
December 6th 2023

Exclusive Telemedicine Use Linked to Less Favorable Glycemic Outcomes for T2D Endocrinology Care

Hayden E. Klein
Adults with type 2 diabetes (T2D) undergoing endocrinology care are more likely to experience less favorable hemoglobin A1c improvements if they only use telemedicine compared with patients using in-person care or a mix of both.
Filling out form | Image credit: Tomasz Papuga – stock.adobe.com
November 29th 2023

Research Points to Potential MCIDs in Diabetes Distress Scale–17

Hayden E. Klein
Researchers identified a value of at least 0.25 to be a minimal clinically important difference (MCID) in diabetes distress, and MCID values of 0.38 and 0.39 for emotional and interpersonal distress subscales and physician and regimen distress subscales, respectively.
Chase D. Hendrickson, MD, MPH
November 21st 2023

Dr Chase Hendrickson Explains Reasons Behind Varying CGM Uptake in Endocrinology, Primary Care Settings

Hayden E. Klein
Chase Hendrickson, MD, MPH, Vanderbilt University Medical Center, attributes gaps in continuous glucose monitoring (CGM) prescribing rates to patient demographics, endocrinologists' longer familiarity with the technology, and the availability of ancillary support in endocrine clinics.
Colorectal screening | Image credit: Richelle – stock.adobe.com
November 14th 2023

Study Reveals Factors That Further Increase Colorectal Cancer Risk for Adults With T2D

Hayden E. Klein
The strongest associations between diabetes and colorectal cancer risk were observed in participants with a recent diabetes diagnosis and those who had not undergone recent colonoscopy, underscoring the significance of cancer screening.
Red FDA approved stamp
November 8th 2023

FDA Approves Diabetes Drug Tirzepatide for Chronic Weight Management

Laura Joszt, MA
Tirzepatide is already approved to treat type 2 diabetes, and is now approved for chronic weight management in adults with obesity or overweight with at least 1 weight-related condition.
Steven Coca, MD, MS, Icahn School of Medicine, Mount Sinai
November 8th 2023

Biomarkers of Kidney Disease Progression Have “Transcendent Signals” Across Subtypes, Says Dr Steven Coca

Laura Joszt, MA Gillian McGovern
Regardless of kidney disease subtype, biomarkers can successfully ascertain risk of kidney disease progression, said Steven Coca, DO, MS, of the Icahn School of Medicine at Mount Sinai.
AJMC
November 2nd 2023

Charitable Medication Distribution Improves Care for Uninsured Patients With Diabetes

Jonathan Hughes, PharmD, BCPS, BCACP Abby Sparkman, PharmD Priscilla Smith, PharmD, BS, BCPPS Tim McCormack, PharmD, BCPS Tavajay Campbell, PharmD, BCACP Hillary Blackburn, PharmD, MBA
This report illustrates how providing vital diabetes medications to uninsured patients through a charitable medication distributor improves clinical outcomes.
AJMC
October 31st 2023

At-Home Hemoglobin A1c Testing During COVID-19 Improved Glycemic Control

Lauren C. LaMonica, MPH Jingwei Ren, MS Nina Jain, MD Eli S. Goldberg, PhD Kyu B. Rhee, MD Paige Wickner, MD Sreekanth K. Chaguturu, MD
Providing at-home hemoglobin A1c test kits increases testing rates and facilitates hemoglobin A1c reduction over time among members of a large commercial health plan with diabetes.
AJMC
October 31st 2023

Safety vs Price in the Generic Drug Market: Metformin

Ben Teasdale, MPhil Amber Hudspeth, MS Kaury Kucera, PhD David Light, BS Jill Nailor, RPh Shannon Williams, BS Arnold Milstein, MD Kevin A. Schulman, MD
The generic drug market focuses on price. However, multiple generic metformin drugs have been recalled due to poor drug quality. The authors examine price and quality after these recalls.
US and Mexico flags | Image Credit: Rawf8 – stock.adobe.com
October 25th 2023

How Can Family Affect Diabetes Management in Mexican American Adults?

Hayden E. Klein
Interviews highlight the importance of culturally-tailored diabetes education to address health care disparities in the Mexican American community.
Steak on cutting board | Image Credit: Rishieka – stock.adobe.com
October 20th 2023

High Red Meat Consumption Linked to Increased Diabetes Risk

Hayden E. Klein
New research found that people who routinely eat high amounts of red meat have a 62% higher risk of developing type 2 diabetes, supporting dietary recommendations to limit red meat consumption.
AJMC
October 19th 2023

Use of Second-Generation Antidiabetic Medication Among a Nationally Representative Sample

Bang Truong, PhD Yuexin Li, MS Jingyi Zheng, PhD Jingjing Qian, PhD
Among individuals with a diagnosis of type 2 diabetes across the United States, income level, hemoglobin A1c, and comorbidity burden were the primary patient-level drivers of the use of newer antidiabetic agents.
What We’re Reading: Alzheimer Blood Tests; Year-Long Adderall Shortage; Type 2 Diabetes Management
October 12th 2023

What We’re Reading: Alzheimer Blood Tests; Year-Long Adderall Shortage; Type 2 Diabetes Management

AJMC Staff
Blood tests offer a less invasive and more accessible means of detecting Alzheimer disease; Democrats address a year-long Adderall shortage; A new study shows significantly improved clinical outcomes in Type 2 diabetes management with a digital behavioral therapy app.
Hospital sign | Image Credit: Spiroview Inc. – stock.adobe.com
October 11th 2023

For Patients With Diabetes, Review Finds CVD to Be Leading Cause of Hospital Admissions

Hayden E. Klein
Ischemic and coronary heart disease were the 2 major cardiovascular disease (CVD) subtypes contributing to hospital admissions among patients with diabetes.
Medical stethoscope and dollar bills | Image Credit: Kuzmick – stock.adobe.com
October 7th 2023

Patients With NASH and Type 2 Diabetes Face Costly Financial Burden

Abigail Brooks, MA
Annualized costs for the 24-month study period were highest among patients with both NASH and T2D, highlighting the incremental cost of adding an additional diagnosis for comorbid NASH or T2D.
Matthew Crowley, MD, MHS, associate professor of medicine, Duke University School of Medicine.
September 24th 2023

Dr Matthew Crowley Discusses Key Advantages and Challenges of Telehealth Among Underserved Populations

Pearl Steinzor
Matthew Crowley, MD, MHS, associate professor of medicine, Duke University School of Medicine, discusses telehealth initiatives at Duke Health, as well as overcoming virtual challenges and barriers that underserved and underinsured patient populations who need diabetes care face.
FDA approved | Image credit: Aquir – stock.adobe.com
September 22nd 2023

FDA Grants Approval for Empagliflozin in Chronic Kidney Disease

Hayden E. Klein
This approval marks the fourth endorsement by the FDA for empagliflozin, all of which have been linked to the EMPOWER program.
Susan Spratt, MD, senior medical director, Duke Population Health Management Office, associate professor of medicine, division of Endocrinology, Metabolism, and Nutrition,
September 17th 2023

Dr Susan Spratt Discusses Diabetes Management Services at Duke Health

Pearl Steinzor
Susan Spratt, MD, senior medical director, Duke Population Health Management Office, breaks down the the prevalence of diabetes in the United States and discusses current diabetes initiatives at Duke Health.
AJMC
September 15th 2023

Measuring Continuity of Care for Diabetes: Which Visits to Include?

Kevin R. Riggs, MD, MPH Caroline A. Presley, MD, MPH April A. Agne, MPH Carrie R. Howell, PhD Lei Huang, PhD, MS, MBA Michael J. Mugavero, MD, MHSc Emily B. Levitan, ScD Andrea L. Cherrington, MD, MPH
This study examined how inclusion of different provider specialties affected Continuity of Care Index values, year-to-year stability, and association with emergency department visits.
Diabetes | Image credit: Minerva Studio - stock.adobe.com
September 13th 2023

PCOS in Pregnant Women With Diabetes Linked to High Insulin Requirements, Weight Gain

Pearl Steinzor
However, women with type 2 diabetes and polycystic ovary syndrome (PCOS) in pregnancy did not have worse neonatal outcomes, a study found.
doctor with tablet pc and pregnant woman at clinic | Image credit: Syda Productions – stock.adobe.com
September 11th 2023

Women With Gestational Diabetes Have Elevated 30-Year Mortality Risk, Study Suggests

Hayden E. Klein
New research suggests an association between gestational diabetes history and mortality over 30 years, regardless of whether it manifests into type 2 diabetes.
Dr Nikolaus Marx: New Recommendations on Lifestyle Modification, Glucose-Lowering Agents for Comorbid Diabetes, CVD
September 6th 2023

Dr Nikolaus Marx: New Recommendations on Lifestyle Modification, Glucose-Lowering Agents for Comorbid Diabetes, CVD

Hayden E. Klein
A patient-centered approach on top of a multifactorial approach will help patients adhere to lifestyle modifications, said Nikolaus Marx, MD, professor of medicine/cardiology and head of the Department of Internal Medicine, University Hospital Aachen, Germany.
AJMC
September 1st 2023

Cost Analysis of Self-Monitoring Blood Glucose in Nonintensively Managed Type 2 Diabetes

David Kerr, MBChB, DM Ian Duncan, PhD Enrico Repetto, MD Rana Maroun, PharmD, PhD Alexander Wu, MSc Christopher Perkins, MS Gert Bergman, PhD, MSc Francesco Giorgino, MD, PhD
Analysis of claims data showed reduced utilization and costs among patients with nonintensively managed type 2 diabetes using self-monitoring of blood glucose compared with continuous glucose monitoring.
AJMC
August 22nd 2023

Predicting Hospital Readmission in Medicaid Patients With Diabetes Using Administrative and Claims Data

Jaehyeon Yun, PhD Giovanni Filardo, PhD, MPH Vishal Ahuja, PhD, MBA, MASc Michael E. Bowen, MD, MPH Daniel F. Heitjan, PhD
A statistical model based entirely on claims data can accurately predict 30-day hospital readmission in Medicaid patients with diabetes.
AJMC
August 21st 2023

Pharmacist-Led Review of Empagliflozin and Ertugliflozin Following Formulary Update

M. Thomas Bateman Jr, PharmD, BCACP Ryan Nguyen, PharmD, BCPS Ashwini B. Navathe, PharmD, BCPS, BCPPS Caitlin McCarthy, PharmD, BCPP
Management of empagliflozin and ertugliflozin may be suboptimal following an insurance carrier’s formulary updates. Pharmacists may improve the management.
AJMC
August 18th 2023

Non–Face-to-Face Care Management and Service Utilization in Patients With Diabetes

Charles Stoecker, PhD Elizabeth Nauman, PhD, MPH Alessandra N. Bazzano, PhD Eboni G. Price-Haywood, MD, MPH Yilin Yoshida, PhD, MPH Lizheng Shi, PhD, MSPharm, MA
CMS began reimbursement for non–face-to-face chronic care management in 2015, and results from Louisiana show that it increases outpatient visits but decreases inpatient and emergency department encounters.
Hand holding a blood glucose meter measuring blood sugar, the background is a stethoscope and chart file | Image Credit: xb100 – stock.adobe.com
August 10th 2023

Experts Call for Health System Action to Reduce Hypoglycemia Risk in Older Adults With Diabetes

Hayden E. Klein
According to one panelist, the leading causes of hypoglycemia in older adults are insufficient nutrition and taking the wrong dose or type of insulin, both of which can be addressed at the patient and system level.
patient sitting on hospital bed
August 4th 2023

Type 2 Diabetes Can Increase Hospital Bed-Days, Study Says

Hayden E. Klein
A Hong Kong study revealed how much type 2 diabetes (T2D) can increase hospital bed-days based on condition, age, sex, and other factors.
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