The AJMC® Diabetes compendium is a comprehensive resource for clinical news and expert insights for the chronic condition.
Gene Factors Into Sex-Related Differences in Cognition Loss in Presence of T2D
Among patients with type 2 diabetes (T2D) and weight issues, cognitive advantages that women hold over men when both are affected are preserved into later life but are eroded for women carrying apolipoprotein E ε4 alleles.
Examination of Marshallese Living in US Illustrates Health Disparities in T2D
A high proportion of Marshallese, or Marshall Islanders, living on the mainland Unites States, have undiagnosed hypertension and type 2 diabetes (T2D), according to findings that will be used to address disparities in Native Hawaiian and Pacific Islander populations.
Can a Machine Learning Model Predict T2D?
A machine learning model using the gut microbiome may serve as a successful predictive measure for type 2 diabetes development.
Early T1D Onset Linked With Shorter Reproductive Periods Among Women
Women who received a type 1 diabetes (T1D) diagnosis prior to menstruation onset exhibited shorter reproductive periods compared with healthy controls.
Low-Carb Diet May Help Achieve Type 2 Diabetes Remission, Study Finds
A review found that a low-carbohydrate diet may lead patients with type 2 diabetes to experience disease remission, potentially providing new insight into how clinicians can help patients better manage their disease, investigators concluded.
Improving Adherence Through Data Analysis: An Interview With Kristin Alvarez, PharmD
Researchers Identify Key Differences in Diabetes Care Quality Between Clinics
Investigators found 10 main themes characterizing the differences between primary care clinics classified as high- and low-performing in distributing diabetes care.
Meal Timing May Impact Metabolic Risk Factors
New research shows eating before 8:30 am may reduce risk factors for type 2 diabetes as individuals who did so exhibited lower blood sugar levels and less insulin resistance.
20-Year Data Highlight Little Progress in Rural Racial Health Disparities
Between 1999 and 2018, Black adults living in rural regions of the United States experienced high mortality rates due to diabetes, high blood pressure, heart disease, and stroke compared with White adults, according to new research published in the Journal of the American College of Cardiology.
Comparing T2D Medication Initiation Patterns Among Medicare Advantage, Commercially Insured Patients
Medicare Advantage beneficiaries with type 2 diabetes (T2D) may be less likely than commercially insured individuals to be treated with newer medications to lower glucose levels, according to results of a retrospective cohort study published in JAMA Network Open.
Behavior-Based Diabetes Management: Impact on Care, Hospitalizations, and Costs
The Diabetes Care Rewards program offers a business case for health plans to promote engagement through use of contingent incentives, thus improving health outcomes and lowering costs.
How Do Screening Methods for Gestational Diabetes Compare?
When comparing 1-step and 2-step approaches for diagnosing gestational diabetes among pregnant women, researchers found no significant between-group differences in the risks of primary outcomes relating to perinatal and maternal complications.
Costs for Commercially Insured Adults Prescribed Second-line Diabetes Medications
Adults with type 2 diabetes who received nonsulfonylurea medications had relative increases in total costs. Receiving newer medication classes led to relatively decreased medical costs.
Exercise Timing Linked to Cardiorespiratory Fitness in Men With T2D
Timing of bout-related moderate-to-vigorous physical activity (MVPA) is associated with cardiorespiratory fitness and cardiovascular risk among men with type 2 diabetes (T2D), independent of bout-related MVPA volume and intensity, according to research published in Diabetes Care.
Use of Diabetes Medications in Traditional Medicare and Medicare Advantage
Medicare Advantage enrollees are more likely to be treated with metformin and sulfonylureas and less likely to receive costly newer medications than those in traditional Medicare.
Caring for the Whole Patient With Diabetes Drives ChristianaCare Pilot Success
Collaboration enabled ChristianaCare to significantly grow its population of patients with well-controlled disease, thanks to a diabetes control roadmap that ensured both physical and emotional health needs were met through interprofessional partnerships.
Mendelian Randomization Study Shows Vitamin D Deficiency Not Associated With T1D
Genetically decreased vitamin D levels are unlikely to have a large effect on risk of type 1 diabetes, according to results of a Mendelian randomization study published in PLOS Medicine.
How Does Maternal Diet Impact Childhood Weight?
Low-quality maternal diets may increase the odds of offspring being considered overweight or obese, according to study results published in BMC Medicine.
Phase 3 Trials Show Lilly’s Tirzepatide Reduces A1C, Body Weight Among Patients With T2D
The SURPASS program, which consists in part of SURPASS-3 and SURPASS-5, is testing the efficacy and safety of tirzepatide, a novel investigational once-weekly dual glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1 receptor agonist.
Trial Finds Semaglutide With Lifestyle Intervention Reduces Body Weight by Nearly 15%
In the placebo-controlled trial, 86% of participants who received semaglutide attained at least a 5% reduction in total body weight.
Prediabetes May Not Necessitate Diabetes Development in Older Adults
Prediabetes may not be a robust diagnostic biomarker for predicting future diabetes development in older adults.
GD May Increase Heart Disease Risk Despite Achieving Normal Blood Glucose Levels
Results of a prospective cohort study suggest history of gestational diabetes (GD) may promote development of atherosclerotic plaque, potentially increasing the risk of future heart disease among women, even in the absence of hyperglycemia.
Recognizing the Role of Systemic Racism in Diabetes Disparities
There needs to be broad acceptance of the role systemic racism plays in social determinants of health in order to improve metabolic outcomes among minority populations in the United States.
Insulin Resistance, Diabetes Strongly Linked With Premature CHD Among Women
A prospective cohort study found that diabetes and insulin resistance were the strongest risk factors for premature onset of coronary heart disease (CHD) among American women. Results were published in JAMA Cardiology.
Metabolic Surgery Superior to Drug Therapy at Controlling Type 2 Diabetes, Study Says
Metabolic surgery is more effective than conventional medical therapy in the long-term control of type 2 diabetes (T2D), according to results of a 10-year follow-up study of a randomized controlled trial published in The Lancet.
Study Weighs Perceived Benefits, Costs of RDM Adoption for Diabetes Management
Results of a vignette-based survey study indicate patients with diabetes require greater health benefits to adopt more intrusive remote digital monitoring (RDM), food monitoring, and real-time feedback by a health care professional.
Trial Finds Bimagrumab Aids Weight Loss in Patients With T2D, Obesity
Results of a phase 2 trial showed that an activin type II receptor blockade, achieved via bimagrumab, led to significant loss of fat mass, gain in lean mass, and metabolic improvements among patients with type 2 diabetes (T2D) and overweight or obesity.
Black Americans With T1D, COVID-19 Have Increased Risk of Hospitalization for DKA
Non-Hispanic Black individuals with type 1 diabetes and coronavirus disease 2019 infections may be more likely to be hospitalized for diabetic ketoacidosis (DKA) compared with non-Hispanic White patients.
ADA Survey Highlights COVID-19’s Impact on Americans With Diabetes
A new American Diabetes Association (ADA) survey highlights how the coronavirus disease 2019 (COVID-19) pandemic took a toll on the population with diabetes, which is one of the most prevalent preexisting conditions in America.
Jardiance 1 Step Closer to FDA Approval for Use in Heart Failure
The FDA today accepted Boehringer Ingelheim and Eli Lilly’s supplemental New Drug Application for Jardiance (empagliflozin), the sodium glucose co-transporter 2 inhibitor being investigated for use in patients with heart failure.
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