The AJMC® HIV compendium is a comprehensive resource for clinical news and expert insights for the condition, including disparities in care, prevention of infection among at-risk groups, and the importance of viral suppression.
May 16th 2024
Patients with HIV who switched to a treatment regimen that included tenofovir alafenamide (TAF) showed improvement in serum markers for hepatic steatosis (HS) among other benefits.
How Were HIV Care Services in South Carolina Interrupted by the COVID-19 Pandemic?
September 1st 2020Results from a recent study in the state show how its HIV service care continuum was affected by the coronavirus disease 2019 pandemic (COVID-19), namely that more than a quarter of HIV clinics had to close completely.
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Short-Term PrEP May Be Effective Alternative Method of HIV Prevention Among MSM
August 19th 2020Gay, bisexual, and other men who have sex with other men (MSM) during episodes of high-risk behavior could benefit from short-term use of preexposure prophylaxis (PrEP) to lessen their chances of contracting HIV, a new study reports.
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Saliva May Be a Reliable Alternative to Blood for HIV Antibody Testing
August 13th 2020HIV-specific antibodies of 3 immunoglobulin isotypes are readily found in human saliva, providing a potential second reliable method of detecting the virus that may be used as a painless alternative to a blood draw.
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HIV Education, Prevention Efforts See Lukewarm Results in Dhaka, Bangladesh
August 7th 2020A 3-year endeavor to scale up HIV prevention and education efforts among men who have sex with men in Dhaka, Bangladesh, showed only modest gains in the country where intercourse with a same-sex partner could mean a lifetime jail sentence.
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Immunosuppression to Blame for Oral Microbiota Change in Children With HIV
August 5th 2020Bacterial changes in the oral cavity from immunosuppression, not HIV itself, are more likely to blame for the greater incidence of oral caries in children 6 months to 6 years, reports a study from the Department of Oral Biology at the Rutgers University School of Dental Medicine.
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NIH Deems Kidney Transplantation Safe Between HIV-Positive Donors and Recipients
July 29th 2020HIV-positive individuals with end-stage kidney disease may now have a larger pool of kidneys available to them, with recent study results from the National Institutes of Health (NIH) showing that kidneys from HIV-positive deceased donors can be used in addition to those from HIV-negative donors.
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What Factors Are Most Likely to Predict Disclosing HIV Status in the Community?
July 26th 2020Having health insurance, a higher level of education, and more money were associated with a greater likelihood of caregivers disclosing their HIV status in the community, either positive or negative, while being male and living in a rural location indicated a lesser likelihood, reports AIDS Research and Therapy.
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Antibody "Cocktail" Could Offer Potent Treatment, Prevention of COVID-19
July 23rd 2020Writing in Nature, scientists found the antibodies fell into 2 distinct groups, targeting different regions of the viral spike. Thus, they say, the battle against coronavirus disease 2019 (COVID-19) could be opened on separate fronts, much like the approach Ho and others have studied in HIV and some forms of cancer.
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Treatment Adherence, Viral Suppression Suffer Due to HIV-Related Stigma in Florida
July 22nd 2020Stigma perpetuated in a health care setting has been linked to greater odds of poor outcomes in the HIV continuum of care for antiretroviral treatment adherence and reduced viral suppression among persons living with HIV in Florida.
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A Computer-Simulation Model Attempts to Reframe Costs, Solutions to Ending HIV in the United States
July 16th 2020To effectively end the HIV epidemic in the United States, combination strategies should be tailored according to need, backed by evidence-based interventions, and scaled according to location, report study results in The Lancet HIV.
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PrEP Use Has Changed Following Implementation of Social Distancing Measures
July 13th 2020A pair of late-breaking abstracts presented during AIDS 2020, this year’s virtual meeting of the International AIDS Society, detailed the effects that the coronavirus disease 2019 pandemic has had on trends in at-risk sexual behaviors and pre-exposure prophylaxis (PrEP) use, both in the United States and in Australia, due to shelter-in-place orders and social distancing.
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Donor Government Funding for HIV Falls
July 9th 2020A recent analysis conducted by the Kaiser Family Foundation and The Joint United Nations Program on HIV/AIDS found donor governments spent $7.8 billion for HIV in 2019, a decrease of $165 million from the previous year. This number is similar to that spent a decade ago, despite a 25% increase of individuals now living with HIV in regions receiving the aid.
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Study Identifies Possible New Patient Phenotype in HIV Space
July 4th 2020Previously associated with elite controller status, having an inherent low viral reservoir is now possibly linked to individuals with chronic HIV infection who initiate treatment with antiretrovirals more than 6 months after becoming infected.
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This Week in Managed Care: June 26, 2020
June 26th 2020This week, the top managed care news included CMS proposing rules for value-based contracting in Medicaid; claims data highlighting racial disparities in COVID-19 effects; an interview with Anthony Fauci, MD, on the progress made against HIV.
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Opioid Use Has a Detrimental Effect on Uptake of Care for Uncontrolled HIV
June 24th 2020Individuals who self-report a problem with drugs, especially opioids, are more likely to have uncontrolled HIV, to not be adherent to antiretroviral therapy, and to engage less in primary care for their infection but more in risky behaviors, including sharing needles and having multiple concurrent sexual partners.
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Fauci: Countless Lives Have Been Saved, but an HIV Vaccine and Cure Remain Elusive
June 21st 2020To mark the 25th anniversary of The American Journal of Managed Care®, we spoke with Anthony Fauci, MD, director of the National Institute of Allergy and Infectious Diseases (NIAID). Fauci has been at NIAID for 36 years, and he gave a keynote address at the 6th International AIDS Conference in San Francisco in 1990. Here he speaks on progress that has been made in the fight against HIV and AIDS, from AZT to Truvada to undetectable viral loads; why there is no cure just yet; and how the first tumultuous years of the AIDS crisis shaped research for decades to come.
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From the Editor-in-Chief: Bigger Questions of Systems, Viruses, and the Lives of Real People
June 19th 2020As I recall the early days of the HIV/AIDS pandemic, what stands out most is its profound human cost and the courage of those who helped our society transcend it. We are in the midst of a time in which the human toll of COVID-19 and the enormity of the path ahead are clear.
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Humility and Hope: Evolution of the HIV Pandemic, From ART to Today's Cancer Cures
June 19th 2020The connections between cancer and HIV/AIDS became clear relatively early in the HIV/AIDS pandemic and continue to this day. Not only were opportunistic infections present in a majority of HIV-infected patients who met the initial diagnostic criteria for AIDS, but several cancer types were far more prevalent as well. While there is still much to understand before HIV is fully conquered, we have already learned a great deal about the pathobiology of this virus that has helped advanced immune-oncological technologies and led to the development of increasingly effective gene therapy delivery systems.
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Challenges and Similarities in HIV, COVID-19 Crises: A Q&A With Anthony Fauci, MD
June 18th 2020To mark the 25th anniversary of The American Journal of Managed Care®, each issue in 2020 will include a special feature: an interview with a thought leader in the world of health care and medicine. The July issue features a conversation with Anthony Fauci, MD, director of the National Institute of Allergy and Infectious Diseases.
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