The AJMC® HIV compendium is a comprehensive resource for clinical news and expert insights for the condition, including disparities in care, prevention of infection among at-risk groups, and the importance of viral suppression.
May 16th 2024
Patients with HIV who switched to a treatment regimen that included tenofovir alafenamide (TAF) showed improvement in serum markers for hepatic steatosis (HS) among other benefits.
Study Evaluates Effectiveness of Digital HIV Care Navigation Intervention
November 16th 2019A recent study, published by JMIR Research Protocols, demonstrated the effectiveness of implementing a digital HIV care navigation intervention for young racial and ethnic minority men and transwomen.
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NIH, Bill and Melinda Gates Foundation Collaborate to Develop Gene-Based HIV Treatment
October 28th 2019The National Institutes of Health (NIH) has announced plans to invest at least $100 million over the next 4 years to develop gene-based therapies for 2 diseases: HIV and sickle cell disease. The Bill and Melinda Gates Foundation will also contribute $100 million to the goal of advancing these potential cures, with an aim toward providing affordable, globally available treatment that will be accessible to patients in low-resource settings.
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Stress at Time of HIV Diagnosis May Affect Later Psychosocial Status
October 26th 2019As HIV infection becomes a chronic illness, assessing psychosocial status regularly and implementing effective interventions aimed at related problems as they arise may be particularly important for people living with HIV to improve their health-related quality of life, a study suggests.
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Universal HIV Testing in EDs Yields New Diagnoses, Linkage to Care in San Diego Hospitals
October 21st 2019While targeted testing for HIV has helped more individuals to be diagnosed and treated, the CDC recommends routine, universal HIV screening for all individuals aged 13 years to 64 years as a way to reach populations who may be less likely to seek out or participate in HIV testing. Emergency departments (EDs) in particular may play an important role in universal screening, as evidenced by the experience of 2 academic EDs in San Diego, California.
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Tesamorelin Shows Effectiveness at Fighting NAFLD in Patients With HIV
October 16th 2019As a result of the study, investigators suggested expanding the indication for tesamorelin (Egrifta) to include people living with HIV who have been diagnosed with nonalcoholic fatty liver disease (NAFLD), a comorbidity in HIV.
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HIV Latent Reservoir Forms Near the Time of ART Initiation, Researchers Find
October 14th 2019While antiretroviral therapy (ART) can suppress HIV infection, ART cannot completely eradicate HIV, which remains in a latent reservoir in CD4-positive T cells during treatment; discontinuation of ART leads to rapid rebound of the virus. This reservoir forms even when ART is initiated early on in the infection, and while the most widely accepted model of how the reservoir forms involves infection of a CD4-positive T cell as it transitions to a resting state, the dynamics and timing of the reservoir’s formation have been largely unknown.
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This Week in Managed Care: October 11, 2019
October 11th 2019This week, the top managed care news included an effort by the Trump administration to bolster Medicare Advantage; an abortion case from Louisiana reached the Supreme Court; the study of adapting to changing oxygen levels wins the Nobel Prize.
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California Becomes First State to Make HIV Prevention Medication Accessible Without a Prescription
October 9th 2019Once the bill goes into effect in January 2020, pharmacists will be able to provide pre-exposure prophylaxis for at least a 30-day supply and up to a 60-day supply and a complete course of post-exposure prophylaxis without a prescription.
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FDA Approves Descovy for HIV Prevention in MSM, Transgender Women
October 3rd 2019The FDA has approved Gilead’s second HIV prevention pill, Descovy, for at-risk adults and adolescents weighing at least 35 kg, excluding those who are at risk of HIV due to vaginal sex because the efficacy of Descovy has not been assessed in this population.
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Tuberculosis Preventive Therapy Heightens Risk of Adverse Outcomes in Pregnant Women With HIV
October 3rd 2019The findings indicate that the initiation of tuberculosis preventive therapy isoniazid during pregnancy carries greater risk than initiation of the treatment during the postpartum period.
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New York Governor Andrew Cuomo said that the state is on track to meet its goal of ending the HIV/AIDS epidemic in New York by 2020; lung damage exhibited by some patients as a result of vaping resembles the damage on lungs exposed to chemical spills or harmful gases; a federal judge has ruled that a Philadelphia nonprofit’s plan to open a supervised injection drug site for drug users does not break federal law.
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Observational Study Results Suggest Most HIV–HIV Kidney Transplants Have Long-term Success
October 3rd 2019The study, which followed 51 people with HIV who received kidney transplants from deceased donors with HIV in South Africa, found that the transplants produced long-term success, with high rates of overall survival and kidney graft survival after 5 years.
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Researchers Identify and Silence Long Noncoding RNA Responsible for HIV Replication
September 27th 2019According to the researchers, the long noncoding RNA, when turned off or deleted, eliminates dormant HIV reservoirs that persist even when patients adhere here to their antiretroviral therapy regimen and are virally suppressed.
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This Week in Managed Care: September 20, 2019
September 20th 2019This week, the top managed care stories included Purdue Pharma filing for bankruptcy; new data showing the number of people who get screened for HIV at least once falls far short of what CDC recommends; findings that most US hospital markets are now highly concentrated.
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Initiating Treatment in EDs Could Be Critical for Containing Spread of HIV
September 19th 2019The researchers of the study argue that emergency departments (EDs) should not just be leveraged to diagnose HIV; they must also be proactive and initiate treatment, as well as facilitate follow-up case management and linkage to care outside of the ED.
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HIV Associated With Significantly Increased Risk of Atrial Fibrillation
September 16th 2019The researchers found that HIV significantly increases the risk of atrial fibrillation—a leading cause of stroke—at the same rate as or higher than known risk factors, including diabetes and hypertension.
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How Many People Actually Get Screened for HIV?
September 14th 2019Using national electronic health record information on more than 40 million patients over a 20-year period, researchers have found that the proportion of Americans older than 18 years who have had a prior HIV test could be as low as 6.4%. However, they noted several limitations of their analysis.
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This Week in Managed Care: August 30, 2019
August 30th 2019This week, the top managed care stories included a huge ruling against one opioid maker and a settlement offer from another; an expert panel calling for broader screening for hepatitis C; a review showing there are more fatal events linked to a multiple sclerosis drug than previously known.
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