HIV

The AJMC® HIV compendium is a comprehensive resource for clinical news and expert insights for the condition, including disparities in care, prevention of infection among at-risk groups, and the importance of viral suppression.

Latest News

Zandraetta Tims-Cook
Contributor: PrEP in Practice – How to Start Conversations About HIV Prevention

June 17th 2025

Learning the best type of HIV prevention for those at highest risk can start with conversations about their options, writes Zandraetta Tims-Cook, MD, MPH, AAHIVS

Vaccine | Image credit: weyo - stock.adobe.com
Cuts to HIV Vaccine Research Come Amid Challenges to Other Vaccines, Treatment

June 13th 2025

Doctor communicating with patient | Image credit: bongkarn - stock.adobe.com
People Living With HIV Communicate Less With Health Care Providers

June 9th 2025

Machine learning | Image credit: putilov_denis - stock.adobe.com
Machine Learning Capable of Predicting Hyperlipidemia in People With HIV

May 28th 2025

Young adult HIV | Image credit: ViDi Studio - stock.adobe.com
Adolescents, Young Adults With HIV at Increased Risk of Mental Health Issues

May 20th 2025

Clarifying USPSTF Recommendations for HIV Pre-Exposure Prophylaxis (PrEP)

This discussion focuses on how to address barriers and disparities as obstacles to using PrEP, with a focus on USPSTF PrEP guidelines and ACA Part 47 for payers and providers.

This multi-stakeholder roundtable panel discussion will focus on how to address barriers and disparities as obstacles to the use of PrEP, with a focus on increased understanding and education around US Preventive Services Task Force (USPSTF) PrEP guidelines and Affordable Care Act Part 47 for payers and providers.
Continuing Medical Education
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June 18th 2025

Navigating the HIV Treatment Frontier: Equipping Managed Care Professionals With Strategies for Innovation, Access, and Adherence

1.5 Credits / HIV/AIDS, Infectious Diseases

More News

Mystery Shopping Reveals Need for Higher-Quality HIV Testing, Counseling Services Among High-risk Group
November 8th 2019

Mystery Shopping Reveals Need for Higher-Quality HIV Testing, Counseling Services Among High-risk Group

Maggie L. Shaw
CDC recommends that young men who have sex with men have an HIV test every 6 months.
Future PrEP Drugs, Delivery Methods, Technologies Target Adherence Issue
November 1st 2019

Future PrEP Drugs, Delivery Methods, Technologies Target Adherence Issue

Allison Inserro
A new review published in The Lancet describes the future landscape of therapeutics in development for what the authors call the next generation of HIV prevention, or PrEP 2.0.
NIH, Bill and Melinda Gates Foundation Collaborate to Develop Gene-Based HIV Treatment
October 28th 2019

NIH, Bill and Melinda Gates Foundation Collaborate to Develop Gene-Based HIV Treatment

Kelly Davio
The National Institutes of Health (NIH) has announced plans to invest at least $100 million over the next 4 years to develop gene-based therapies for 2 diseases: HIV and sickle cell disease. The Bill and Melinda Gates Foundation will also contribute $100 million to the goal of advancing these potential cures, with an aim toward providing affordable, globally available treatment that will be accessible to patients in low-resource settings.
Stress at Time of HIV Diagnosis May Affect Later Psychosocial Status
October 26th 2019

Stress at Time of HIV Diagnosis May Affect Later Psychosocial Status

AJMC Staff
As HIV infection becomes a chronic illness, assessing psychosocial status regularly and implementing effective interventions aimed at related problems as they arise may be particularly important for people living with HIV to improve their health-related quality of life, a study suggests.
Universal HIV Testing in EDs Yields New Diagnoses, Linkage to Care in San Diego Hospitals
October 21st 2019

Universal HIV Testing in EDs Yields New Diagnoses, Linkage to Care in San Diego Hospitals

Kelly Davio
While targeted testing for HIV has helped more individuals to be diagnosed and treated, the CDC recommends routine, universal HIV screening for all individuals aged 13 years to 64 years as a way to reach populations who may be less likely to seek out or participate in HIV testing. Emergency departments (EDs) in particular may play an important role in universal screening, as evidenced by the experience of 2 academic EDs in San Diego, California.
Tesamorelin Shows Effectiveness at Fighting NAFLD in Patients With HIV
October 16th 2019

Tesamorelin Shows Effectiveness at Fighting NAFLD in Patients With HIV

Allison Inserro
As a result of the study, investigators suggested expanding the indication for tesamorelin (Egrifta) to include people living with HIV who have been diagnosed with nonalcoholic fatty liver disease (NAFLD), a comorbidity in HIV.
HIV Latent Reservoir Forms Near the Time of ART Initiation, Researchers Find
October 14th 2019

HIV Latent Reservoir Forms Near the Time of ART Initiation, Researchers Find

Kelly Davio
While antiretroviral therapy (ART) can suppress HIV infection, ART cannot completely eradicate HIV, which remains in a latent reservoir in CD4-positive T cells during treatment; discontinuation of ART leads to rapid rebound of the virus. This reservoir forms even when ART is initiated early on in the infection, and while the most widely accepted model of how the reservoir forms involves infection of a CD4-positive T cell as it transitions to a resting state, the dynamics and timing of the reservoir’s formation have been largely unknown.
This Week in Managed Care: October 11, 2019
October 11th 2019

This Week in Managed Care: October 11, 2019

This week, the top managed care news included an effort by the Trump administration to bolster Medicare Advantage; an abortion case from Louisiana reached the Supreme Court; the study of adapting to changing oxygen levels wins the Nobel Prize.
California Becomes First State to Make HIV Prevention Medication Accessible Without a Prescription
October 9th 2019

California Becomes First State to Make HIV Prevention Medication Accessible Without a Prescription

Jaime Rosenberg
Once the bill goes into effect in January 2020, pharmacists will be able to provide pre-exposure prophylaxis for at least a 30-day supply and up to a 60-day supply and a complete course of post-exposure prophylaxis without a prescription.
What We're Reading: Juul Sued by School Districts; Virus Linked to Acute Flaccid Myelitis; HIV Prevention Drugs
October 8th 2019

What We're Reading: Juul Sued by School Districts; Virus Linked to Acute Flaccid Myelitis; HIV Prevention Drugs

AJMC Staff
E-cigarette manufacturer Juul is being sued by 3 school districts; virus linked as potential cause of acute flaccid myelitis; HIV prevention drugs will be available without prescription in California
FDA Approves Descovy for HIV Prevention in MSM, Transgender Women
October 3rd 2019

FDA Approves Descovy for HIV Prevention in MSM, Transgender Women

Jaime Rosenberg
The FDA has approved Gilead’s second HIV prevention pill, Descovy, for at-risk adults and adolescents weighing at least 35 kg, excluding those who are at risk of HIV due to vaginal sex because the efficacy of Descovy has not been assessed in this population.
Tuberculosis Preventive Therapy Heightens Risk of Adverse Outcomes in Pregnant Women With HIV
October 3rd 2019

Tuberculosis Preventive Therapy Heightens Risk of Adverse Outcomes in Pregnant Women With HIV

Jaime Rosenberg
The findings indicate that the initiation of tuberculosis preventive therapy isoniazid during pregnancy carries greater risk than initiation of the treatment during the postpartum period.
What We're Reading: Ending NY HIV Epidemic; Vaping-Related Lung Damage; Judge Clears Supervised Injection Drug Site
October 3rd 2019

What We're Reading: Ending NY HIV Epidemic; Vaping-Related Lung Damage; Judge Clears Supervised Injection Drug Site

AJMC Staff
New York Governor Andrew Cuomo said that the state is on track to meet its goal of ending the HIV/AIDS epidemic in New York by 2020; lung damage exhibited by some patients as a result of vaping resembles the damage on lungs exposed to chemical spills or harmful gases; a federal judge has ruled that a Philadelphia nonprofit’s plan to open a supervised injection drug site for drug users does not break federal law.
Observational Study Results Suggest Most HIV–HIV Kidney Transplants Have Long-term Success
October 3rd 2019

Observational Study Results Suggest Most HIV–HIV Kidney Transplants Have Long-term Success

Jaime Rosenberg
The study, which followed 51 people with HIV who received kidney transplants from deceased donors with HIV in South Africa, found that the transplants produced long-term success, with high rates of overall survival and kidney graft survival after 5 years.
Researchers Identify and Silence Long Noncoding RNA Responsible for HIV Replication
September 27th 2019

Researchers Identify and Silence Long Noncoding RNA Responsible for HIV Replication

Jaime Rosenberg
According to the researchers, the long noncoding RNA, when turned off or deleted, eliminates dormant HIV reservoirs that persist even when patients adhere here to their antiretroviral therapy regimen and are virally suppressed.
Researchers Identify Significant Prevalence of HIV-Transmitted Drug Resistance
September 26th 2019

Researchers Identify Significant Prevalence of HIV-Transmitted Drug Resistance

Jaime Rosenberg
Among 206 people visiting a county HIV clinic between 2006 and 2013, there was an overall 17.5% prevalence of transmitted drug resistance.
This Week in Managed Care: September 20, 2019
September 20th 2019

This Week in Managed Care: September 20, 2019

This week, the top managed care stories included Purdue Pharma filing for bankruptcy; new data showing the number of people who get screened for HIV at least once falls far short of what CDC recommends; findings that most US hospital markets are now highly concentrated.
Initiating Treatment in EDs Could Be Critical for Containing Spread of HIV
September 19th 2019

Initiating Treatment in EDs Could Be Critical for Containing Spread of HIV

Jaime Rosenberg
The researchers of the study argue that emergency departments (EDs) should not just be leveraged to diagnose HIV; they must also be proactive and initiate treatment, as well as facilitate follow-up case management and linkage to care outside of the ED.
HIV Associated With Significantly Increased Risk of Atrial Fibrillation
September 16th 2019

HIV Associated With Significantly Increased Risk of Atrial Fibrillation

Jaime Rosenberg
The researchers found that HIV significantly increases the risk of atrial fibrillation—a leading cause of stroke—at the same rate as or higher than known risk factors, including diabetes and hypertension.
How Many People Actually Get Screened for HIV?
September 14th 2019

How Many People Actually Get Screened for HIV?

Jaime Rosenberg
Using national electronic health record information on more than 40 million patients over a 20-year period, researchers have found that the proportion of Americans older than 18 years who have had a prior HIV test could be as low as 6.4%. However, they noted several limitations of their analysis.
People Living With HIV Face Significant Burden of Kidney Disease, Researchers Say
September 11th 2019

People Living With HIV Face Significant Burden of Kidney Disease, Researchers Say

Jaime Rosenberg
Cumulative viral load was associated with increased risk of kidney disease, suggesting that early viral suppression could decrease incidence of disease.
While Adherence to ART Regimens Has Improved Among People With HIV, Rates Remain Suboptimal
September 7th 2019

While Adherence to ART Regimens Has Improved Among People With HIV, Rates Remain Suboptimal

Jaime Rosenberg
The proportion of people living with HIV with more than 90% adherence to antiretroviral therapy (ART) increased from 33.5% in 2001 to 52.4% in 2010.
EMERALD Subgroup Analyses Demonstrate Safety, Efficacy of Switching Certain Patients With HIV to Symtuza
September 4th 2019

EMERALD Subgroup Analyses Demonstrate Safety, Efficacy of Switching Certain Patients With HIV to Symtuza

Jaime Rosenberg
New subgroup analyses from the phase 3 EMERALD trial are supporting the safety and efficacy of switching treatment-experienced, virally suppressed patients to the therapy.
Top 5 AJMC® Articles of August 2019
August 31st 2019

Top 5 AJMC® Articles of August 2019

Here are the top 5 articles for the month of August.
This Week in Managed Care: August 30, 2019
August 30th 2019

This Week in Managed Care: August 30, 2019

This week, the top managed care stories included a huge ruling against one opioid maker and a settlement offer from another; an expert panel calling for broader screening for hepatitis C; a review showing there are more fatal events linked to a multiple sclerosis drug than previously known.
People Living With HIV in New York City Still Dying From Infections, Not Just Old Age
August 30th 2019

People Living With HIV in New York City Still Dying From Infections, Not Just Old Age

Jaime Rosenberg
The researchers, who used autopsy reports of 252 people who died of AIDS in New York City between 1984 and 2016, found that infections associated with the virus are still the leading cause of death for the patient population in the state.
Understanding Disparities in HIV Outcomes to Drive Testing, Care Linkage Program Efforts
August 27th 2019

Understanding Disparities in HIV Outcomes to Drive Testing, Care Linkage Program Efforts

Jaime Rosenberg
Using 2 decades' worth of data, researchers were able to identify disparities in HIV outcomes across more than 25,000 people living with HIV in Tennessee.
Medicaid Expansion Linked to Increased HIV Testing
August 24th 2019

Medicaid Expansion Linked to Increased HIV Testing

Jaime Rosenberg
An analysis of data from between 2010 and 2017 found that Medicaid expansion promoted HIV testing without increasing HIV risk behavior among nonelderly adults.
Clinical Trial Participation Reduces Alcohol Intake, Improves HIV Outcomes in Women Regardless of Treatment Type
August 23rd 2019

Clinical Trial Participation Reduces Alcohol Intake, Improves HIV Outcomes in Women Regardless of Treatment Type

Jaime Rosenberg
Women participating in a randomized clinical trial were able to significantly reduce their alcohol intake regardless of medication assignment and subsequently improve rates of viral suppression.
FDA Panel Backs Use of Descovy for HIV Prevention in Men, Transgender Women
August 17th 2019

FDA Panel Backs Use of Descovy for HIV Prevention in Men, Transgender Women

Jaime Rosenberg
The panel voted against recommending the prevention pill for use in cisgender women due to inadequate data on efficacy in this patient population.
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