The AJMC® Multiple Sclerosis compendium is a comprehensive resource for clinical news and expert insights for the disabling disease that impacts the brain and spinal cord.
March 19th 2024
Results from this cohort study found that levels of glial fibrillary acid protein, cerebral spinal fluid, and neurofilament heavy chain are distinguishable biomarkers that are associated with disease outcomes in multiple sclerosis (MS).
A Managed Care Focus on Assessing the Armamentarium for Multiple Sclerosis to Better Individualize Treatment
1.5 Credits / Neurology
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The Promising Role of Novel and Emerging Therapies for Amyotrophic Lateral Sclerosis: Clinical and Managed Care Insights
1.0 Credit / Neurology
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Strategies for the Management and Treatment of ALS: The Value of Early Diagnosis and Clinical Intervention
3.0 Credits / Neurology
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Leveraging Managed Care to Optimize Best Practices in the Treatment of Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)
1.0 Credit / Neurology
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Improving Outcomes and Quality of Care in Spinal Muscular Atrophy: Updates in Treatment Advances
2.0 Credits / Neurology
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New and Emerging Treatment Strategies for Myasthenia Gravis: The Role of the Specialty Pharmacist
1.0 Credit / Neurology
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Improving Treatment Access for Spinal Muscular Atrophy: How Managed Care Strategies Can Ease Clinical and Caregiver Burden
1.5 Credits / Neurology
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Assessing the Treatment Landscape for Multiple Sclerosis to Better Individualize Care
1.5 Credits / Neurology
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Study: Network Representation Learning Could Help Identify MS-Related Genes
May 17th 2020Identifying the particular genes at play in multiple sclerosis (MS) could lead to a better understanding of the disease, and possibly better therapies for it. A new paper proposes network representation learning as the best method to identify those genes.
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Patients With MS Have Increased Risk for Cardiovascular Disease, Related Mortality
May 13th 2020Patients with multiple sclerosis (MS) had a 3.5-fold increase in all-cause mortality and a 1.5-fold increase in cardiovascular disease mortality, compared with those without MS, even after controlling for traditional risk factors, and women were more at risk than men. Statins were linked with lowering the mortality risk.
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Multidisciplinary, Holistic Approach Appears Effective in MS Treatment
May 13th 2020Almost twice as many young women than men account for the 60% of Canadian adults with multiple sclerosis (MS) diagnosed between ages 20 and 49 years. Researchers developed an expert review of the most common comorbidities, as well as effective management styles available.
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Patients With MS Should Not Stop DMT Because of Pandemic, Experts Say
May 1st 2020In a commentary published in Multiple Sclerosis and Related Disorders, experts addressed common concerns individuals with multiple sclerosis (MS) might have when it comes to the coronavirus disease 2019 (COVID-19) pandemic and the use of disease-modifying therapies (DMTs).
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How Has COVID-19 Changed Multiple Sclerosis Care?
April 25th 2020Online systems, including telehealth, are imperative to maintaining optimal care for patients with multiple sclerosis (MS) during the coronavirus disease 2019 (COVID-19) pandemic, said June Halper, MSN, APN-C, MSCN, FAAN, chief executive officer, Consortium of Multiple Sclerosis Centers, in an interview with The American Journal of Managed Care® (AJMC®).
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FDA Approves Ozanimod for Patients With RMS
March 26th 2020The FDA approved Bristol Myers Squibb’s ozanimod (Zeposia) 0.92 mg as an oral treatment for relapsing forms of multiple sclerosis (RMS). Ozanimod can be used to treat clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive disease.
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Researchers Use Virtual Reality to Detect Early MS Balance Problems
March 24th 2020Researchers at the University of North Carolina School of Medicine found that falls simulated through virtual reality could enable early detection of balance problems in patients with multiple sclerosis (MS), according to a study published in PLoS One.
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Synthetic MRI Can Be Useful in Calculating Myelin Volume Fraction, MS Study Says
March 23rd 2020A new study compares synthetic magnetic resonance imaging (SyMRI) to other techniques for measuring myelin volume fraction in patients with multiple sclerosis (MS). The data indicate the technique is effective.
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Multisensor Tool Accurately Measures MS Limb Dysfunction
March 3rd 2020Researchers developed a multisensor tool that quickly and simply records motor changes in patients with multiple sclerosis (MS), according to a study recently published in Annals of Clinical and Translational Neurology. Researchers hope the introduction of the device will lead to future developments in neurological vital signs using wearable technology.
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Aspects of Epstein-Barr Virus, Together and Independently, Increase Risk of MS
February 27th 2020Researchers determined 2 aspects of Epstein-Barrvirus, levels of anti–Epstein-Barr virus nuclear antigen-1 antibodies and history of infectious mononucleosis, act together and independently to increase risk of multiple sclerosis, according to a study published in Frontiers in Neurology.
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Study Examines Link Between MS Survival Rate, Gastrostomy Tube Use
February 11th 2020Patients younger than 50 years who have multiple sclerosis (MS) who receive a gastrostomy tube to enable home enteral feeding live longer than those older than 50 years, according to a study published in Multiple Sclerosis Journal- Experimental, Translational, Clinical.
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Study With MS Implications Shows How Microglia Limit Macrophage Infiltration After Demyelination
February 8th 2020Scientists have long known that both microglia and blood-derived macrophages play roles in how the central nervous system responds to demyelination, which occurs in multiple sclerosis. A new study explains how the two interact.
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Brain Fluid Flow Associated With MS Pathogenesis, Progression
February 5th 2020Researchers determined that patients with multiple sclerosis (MS) present with significant Aqueduct of Sylvius enlargement over time, which may be attributable to regional atrophy changes and ex vacuo expansion of the aqueduct, according to a study recently published in Fluids and Barriers of the CNS.
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Immune System Changes May Increase Efficacy of Treatment for Secondary Progressive MS
January 25th 2020Shifting towards an anti-inflammatory and suppressive homeostatic immune system may contribute to increased clinical efficacy of siponimod in patients with secondary progressive multiple sclerosis (SPMS), a recent study in JCI Insight reported.
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MTX Treatment May Increase Risk of Developing Late Left Ventricular Dysfunction in Patients with MS
January 20th 2020Patients with Multiple sclerosis (MS) treated with mitoxantrone (MTX)—an antracyclin drug used to treat chronic refractory MS—may be at an increased risk of developing early and late left ventricular (LV) dysfunction, suggesting the need for these patients to be periodically evaluated for complications, a recent study found.
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Researchers Develop Trial Protocol on Ketogenic and Fasting Diets for Patients With MS
January 17th 2020For patients with multiple sclerosis, ketogenic diets and fasting diets may be potentially safe and inexpensive complementary treatment options. However, additional clinical studies and data are needed to prove this theory.
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