Multiple Sclerosis

The AJMC® Multiple Sclerosis compendium is a comprehensive resource for clinical news and expert insights for the disabling disease that impacts the brain and spinal cord.

Latest News

ICYMI: Highlights From ACTRIMS 2024
ICYMI: Highlights From ACTRIMS 2024

December 12th 2024

Read about the diverse array of research presented at this year's meeting, including novel technological advancements and insights into disease progression in multiple sclerosis (MS).

Hamas' assault on Israel on October 7, 2023, was the deadliest attack on Jewish people this century | image credit: CYBERUSS - stock.adobe.com
October 7 Hamas Terrorist Attack Exacerbated MS Severity

December 11th 2024

covid-19 vaccine | Image credit: Leigh Prather - stock.adobe.com
Evaluating COVID-19 Vaccination Safety in Multiple Sclerosis

December 1st 2024

3d illustration of a b cell-sebastianlaulitzki-stock.adobe.com.jpeg
sGFAP May Predict Progression Independent of Relapse in BCDT-Treated MS

November 29th 2024

Word Biomarkers next to a DNA strand | Image credit: iQoncept - stock.adobe.com
Researchers Outline Promising Biomarkers Throughout Course of MS

November 26th 2024

Examining the Role of a Novel Class of Medications for the Management of Multiple Sclerosis

This video series provides an in-depth look at multiple sclerosis, covering its impact, pathophysiology, treatment strategies, unmet needs, patient satisfaction, and future research. Gain key insights into managing and understanding this condition.

This video series provides an in-depth look at multiple sclerosis, covering its impact, pathophysiology, treatment strategies, unmet needs, patient satisfaction, and future research. Gain valuable insights into managing and understanding this complex condition.
Continuing Medical Education
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December 13th 2024

Exploring Transthyretin-Mediated Amyloidosis and Its Phenotypes: A Comprehensive Approach to Patient Treatment

1.5 Credits / Cardiology, Neurology, Rare Diseases
December 13th 2024

The Role of the Specialty Pharmacist in Optimizing Treatment for Amyotrophic Lateral Sclerosis: The Impact of Early Intervention, Patient-Centered Care, and Disease-Modifying Therapies in Slowing Disease Progression

1.0 Credit / Neurology
December 13th 2024

Advancing Targeted Therapies Aimed at Smoldering Disease in Multiple Sclerosis

1.0 Credit / Immunology, Neurology
December 13th 2024

The Economics of Transthyretin-Mediated Amyloidosis: Balancing Equity and Access in Resource Allocation

1 Credit / Cardiology, Neurology

More News

Dr Ruth Ann Marrie
November 17th 2020

Dr Ruth Ann Marrie on Comorbidities Affecting MS Treatment Decisions

Ruth Ann Marrie, MD, PhD, director of the Multiple Sclerosis Clinic at the University of Manitoba, discusses how comorbidities affect treatment and options for patients with multiple sclerosis (MS).
Swedish Study Examines Impact of Comorbidities on Cost of MS Over Time
November 13th 2020

Swedish Study Examines Impact of Comorbidities on Cost of MS Over Time

Allison Inserro
Which types of comorbidities have the greatest impact on direct and indirect costs of multiple sclerosis (MS) over time?
Dr Patricia Coyle
November 11th 2020

Dr Patricia Coyle on Escalation vs High-Efficacy Induction in MS

Patricia K. Coyle, MD, of Stony Brook University Neurosciences Institute, explains how studies are trying to answer a debate about 2 approaches to treat multiple sclerosis (MS).
Dr Ruth Ann Marrie
November 7th 2020

Dr Ruth Ann Marrie Discusses Comorbidities in Multiple Sclerosis

Ruth Ann Marrie, MD, PhD, director of the Multiple Sclerosis Clinic at the University of Manitoba, speaks about the overall prevalence of comorbidities in patients with multiple sclerosis (MS).
Woman in pain
November 7th 2020

Adverse Childhood Experiences More Common in MS, Study Says

AJMC Staff
The study sought to determine if 2 specific types of adverse childhood experiences, abuse and neglect, are linked with multiple sclerosis (MS) and other immune-mediated inflammatory diseases.
Damaged nerves
October 31st 2020

New Recommendations Open Door a Bit to Stem Cell Transplant for MS

AJMC Staff
The procedure might work best in patients who have had multiple sclerosis (MS) for less than 10 years, the report said.
John Corboy, MD, University of Colorado Denver
October 30th 2020

Dr John Corboy on Probing Patient Quality of Life Off Medication for MS

Quality of life for patients with multiple sclerosis (MS) could be better when they are off medication because they will not have adverse effects related to those medications, said John Corboy, MD, professor of neurology, University of Colorado Denver, School of Medicine.
Cell division
October 24th 2020

MS Research Examines PPD, Ozanimod in Pregnancy

AJMC Staff
Two abstracts presented at a recent multiple sclerosis meeting examined depression in pregnancy and pregnancy outcomes in ozanimod trials.
Infant
October 24th 2020

Pregnancy Can Delay MS Onset by 3 Years, Study Says

Allison Inserro
The researchers noted that although it is known that pregnancy is linked to reduced MS activity, the effect of pregnancy before MS diagnosis is unclear.
Study Findings Highlight Differences in MS Characteristics Between Sex, Disease Course
October 15th 2020

Study Findings Highlight Differences in MS Characteristics Between Sex, Disease Course

Jaime Rosenberg
Differences in clinical and demographic characteristics between men and women with multiple sclerosis (MS) are more prevalent regarding disease course than they are when stratifying by sex.
John Corboy, MD, Rocky Mountain MS Center
October 13th 2020

Dr John Corboy Forecasts Promising Developments in Multiple Sclerosis

Rebooting the immune system is an exciting approach, noted John Corboy, MD, professor of neurology, University of Colorado Denver, School of Medicine, and co-director of the Rocky Mountain MS Center at Anschutz Medical Campus.
John Corboy, MD, Rocky Mountain MS Center
October 9th 2020

Dr John Corboy: Why Disease-Modifying Therapy Efficacy Varies With Age

Older individuals need medications that focus on effects inside the nervous system, explained John Corboy, MD, of University of Colorado Denver, School of Medicine, and Rocky Mountain MS Center at Anschutz Medical Campus.
patient and doctor
October 7th 2020

Studies Confirm Long-term Safety, Efficacy of Ozanimod in Relapsing Forms of MS

Laura Joszt, MA
Research on the long-term use of ozanimod in relapsing forms of multiple sclerosis (MS) has shown the treatment is effective with no new safety concerns.
Levels of MS Biomarker Rise When DMTs Stop in Pregnancy, Study Notes
October 3rd 2020

Levels of MS Biomarker Rise When DMTs Stop in Pregnancy, Study Notes

AJMC Staff
A recent study explored whether interrupting disease-modifying therapies (DMTs) because of pregnancy leads to increased levels of a specific biomarker of neuroaxonal injury seen in MS.
Dr Burcu Zeydan Discusses Factors in Managing Older Patients With MS
September 29th 2020

Dr Burcu Zeydan Discusses Factors in Managing Older Patients With MS

Tailoring treatment to individual patients is the ultimate goal in the complex decision-making process of managing progressive multiple sclerosis (MS), noted Burcu Zeydan, MD, assistant professor of neurology, assistant professor of radiology, Mayo Clinic.
Ocrelizumab, Rituximab Linked With More Severe COVID-19 in Multiple Sclerosis
September 25th 2020

Ocrelizumab, Rituximab Linked With More Severe COVID-19 in Multiple Sclerosis

Allison Inserro
The results were shared as part of the MSVirtual2020: 8th Joint ACTRIMS-ECTRIMS Meeting, which is concluding Saturday with a special session about coronavirus disease 2019 (COVID-19).
Picture of open office
September 24th 2020

People With MS Face Higher Rates of Harassment, Criticism at Work Than Healthy Employees

Skylar Jeremias
Patients with multiple sclerosis (MS) reported higher rates of harassment and criticism in the workplace than their healthy counterparts, even after informing employers and coworkers about their diagnosis.
Dr Burcu Zeydan Discusses How, Why Postrelapse Recovery Potential Declines With Older Age in MS
September 23rd 2020

Dr Burcu Zeydan Discusses How, Why Postrelapse Recovery Potential Declines With Older Age in MS

Relapse at an older age can significantly contribute to a worsening of multiple sclerosis (MS), explained Burcu Zeyda, MD, assistant professor of neurology, assistant professor of radiology, at Mayo Clinic.
Patricia K. Coyle, MD, screenshot
September 18th 2020

Dr Patricia Coyle Underscores the Importance of Diagnosing and Treating MS Early

Emerging data is showing that treatment within 6 months of presentation of multiple sclerosis (MS) is ideal, explained Patricia K. Coyle, MD, of Stony Brook University Neurosciences Institute.
Combined Training Program Improves Balance, Static Strength in Patients With MS
September 11th 2020

Combined Training Program Improves Balance, Static Strength in Patients With MS

Jaime Rosenberg
Results of a combined training program in 17 patients with multiple sclerosis indicate patients reap benefits from daily activities like walking or sitting-to-standing, and show the program reduces the dual-task cost of performing cognitive tasks while walking.
Case Study Highlights Possible Relationship Between MS, IBD
September 5th 2020

Case Study Highlights Possible Relationship Between MS, IBD

Jaime Rosenberg
The authors suggest that recognizing the possible link may help identify patients at greater risk, although they do caution that larger studies are needed.
Hands
September 4th 2020

Engineered Gloves Show Promise at Measuring MS Limb Disability

AJMC Staff
A small study says that gloves with sensors could measure impairments in hand function and may have advantages over standard methods.
Patients, Physicians Largely Agree on Presence of MS Relapse, Analysis Finds
August 29th 2020

Patients, Physicians Largely Agree on Presence of MS Relapse, Analysis Finds

Jaime Rosenberg
Patients were more likely to report more relapses of multiple sclerosis than physicians.
European Study Finds Patients With MS Adhere Better to Oral Therapies
August 23rd 2020

European Study Finds Patients With MS Adhere Better to Oral Therapies

Allison Inserro
Adherence to multiple sclerosis (MS) therapy is linked with improved clinical outcomes, better quality of life, lower health care costs, and other benefits.
FDA Approves Ofatumumab for Relapsing MS
August 21st 2020

FDA Approves Ofatumumab for Relapsing MS

AJMC Staff
For multiple sclerosis, the therapy will be sold as Kesimpta by Novartis; it is administered by patients once a month through the Sensoready autoinjector pen.
THC, CBD Combo Eases MS Symptoms, Extends Cutaneous Silent Period
August 20th 2020

THC, CBD Combo Eases MS Symptoms, Extends Cutaneous Silent Period

Jaime Rosenberg
A combination of delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD) relieved certain neurophysiological symptoms affecting patients with secondary progressive multiple sclerosis (MS).
Question mark
August 15th 2020

Which Factors of MS Treatment Satisfaction Have Strongest Effect on HRQOL?

Allison Inserro
Certain aspects of satisfaction with multiple sclerosis (MS) treatment can impact health-related quality of life (HRQOL).
Brain picture
August 14th 2020

Measuring Gray Matter in the Brain to Predict MS Decline

Allison Inserro
The thalamus is among the first brain areas to atrophy in multiple sclerosis (MS); this study wanted to know if measuring this loss can predict future disability.
Do Stressful Life Events Trigger Later MS Diagnosis?
August 8th 2020

Do Stressful Life Events Trigger Later MS Diagnosis?

Allison Inserro
Study Describes Ozanimod’s Mechanism of Action in Relapsing MS
August 6th 2020

Study Describes Ozanimod’s Mechanism of Action in Relapsing MS

Jared Kaltwasser
A new analysis offers insights into how ozanimod works in patients with relapsing multiple sclerosis, as well as the impact of higher dosage.
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