The AJMC® Ophthalmology compendium is a comprehensive resource for clinical news and expert insights for treatment of disorders of the eye.
Ophthalmology Overview: Racial Inequities in Ocular Health Care, Eye Implications of Alzheimer Disease, and More
Highlighting the latest ophthalmology-related news reported across MJH Life Sciences™.
Preservative-Free Beta-blockers Appear to Hold Up Well Against Preserved Formulations in Treating Glaucoma
A new meta-analysis finds rigorous evidence lacking; however, existing data suggest preservative-free formulations of beta-blockers may work just as well as preserved beta-blockers in reducing intraocular pressure.
Ophthalmology Overview: Early Diagnosis of Blinding Diseases, Increasing Access to Eye Care, and More
Ophthalmology Overview: Unraveling Biological Pathways of Glaucoma, Classification for Uveitis Subtypes, and More
New Study Data May Help Shape Treatments for Ocular Hypertension
Over 20 years, 1 in 4 patients with ocular hypertension suffered visual field loss from primary open-angle glaucoma, according to a new study.
Ophthalmology Overview: Addressing Dry Eye in Sjogren Syndrome, Chronic Uveitis Treatment, and More
Experts Develop Classification Criteria to Distinguish 25 Most Common Uveitides
Classification criteria developed using machine learning will allow doctors to conduct disease-specific research about this collection of inflammatory eye diseases.
Ophthalmology Overview: Bevacizumab for Wet AMD, AI in Retinal Disease Management, and More
Lighting System Quality May Impact Color Discrimination in Patients With Glaucoma
Patients with glaucoma who were tested under a quantum dot LED were able to better distinguish differences in color, indicating that the quality of light systems may have an impact on color discrimination.
Ophthalmology Overview: Gene Therapy Partially Restores Vision in Blind Patient, Presbyopia Therapy, and More
Sex Likely Not a Disease-Modifying Factor Among Women, Men With Stargardt Disease
A reported association between sex and mild ABCA4 alleles among patients with Stargardt disease did not hold up upon reevaluation.
What We’re Reading: Restoring Eyesight; New Moderna Vaccine Indication Possible; COVID-19 Origin Investigation
Optogenics was used to partially restore a blind man’s eyesight; the FDA could soon approve Moderna’s COVID-19 vaccine for use among adolescents; HHS calls for a new investigation into COVID-19’s origins.
Ophthalmology Overview: COVID-19 Infection in Eye Cells, Vision Loss and Blindness Prevalence, and More
Novel Method Evaluates Progression of Sickle Cell Retinopathy
The technique uses optical coherence tomography angiography to assess the motion of blood flow, instead of static images.
Ophthalmology Overview: Progress in Diabetic Retinopathy Management, Nurse Involvement in Retinal Care, and More
RVO Stabilizes, but Does Not Improve, With Dexamethasone Implant, Study Says
Intravitreal dexamethasone implants stabilized, but did not improve, vision for most patients with macular edema due to retinal vein occlusion (RVO).
Racial, Ethnic Disparities Seen in Ophthalmology Drug Trials, Study Says
Blacks and Hispanics were underrepresented in relation to their US racial distribution in clinical trials for ophthalmology drug approvals from 2000 to 2020.
Examining the Relationship Between Anti-VEGF Drugs and Major Cardiovascular Events
According to a recent review, intravitreal anti-vascular endothelial growth (anti-VEGF) drugs were not associated with an increase in major cardiovascular events.
OCT Easier on Infants Than Typical US Method in Determining ROP, Study Says
Optical coherence tomography (OCT) appears to be less stressful to preterm infants than ocular indirect ophthalmoscopy (BIO) in assessing retinopathy of prematurity (ROP).
Low Rate of Ocular Abnormalities Seen Among Newborns Exposed to SARS-CoV-2 In Utero
A study of newborns exposed to SARS-CoV-2, the virus that causes COVID-19, during gestation found few instances of ocular abnormalities, with none detected in exposed infants who testing positive.
Optimal Oxygen Saturation to Ward Off ROP Remains Unknown
Higher oxygen saturation targets are linked with greater progression in some cases of retinopathy of prematurity (ROP), but the incidence remains stable.
Evaluating Cost Savings of Adenoviral Conjunctivitis PCR Testing Among Employees
Polymerase chain reaction testing of suspected cases of adenoviral conjunctivitis in a hospital setting resulted in large cost savings by avoiding unnecessary employee furloughs.
Therapy Slows Diabetic Retinopathy but Vision Loss Benefit No Better Than Regular Care
More information will come from 4-year results, which will be critical to assess whether there is any long-term benefit to visual acuity using aflibercept.
Machine Learning Helps Identify Eyes With Pathologic Myopia
Using a support vector machine model, researchers were able to distinguish between eyes with pathologic myopia and healthy myopia.
Formulas May Predict Visual Acuity in Patients With Astigmatism
Researchers developed regression formulas that may be clinically beneficial for estimating visual prognosis after astigmatic correction and determining the surgical indication of astigmatic correction.
Study Finds Higher Rates of Hearing Loss Associated With Teprotumumab
Study findings presented at ENDO 2021, the Endocrine Society's annual meeting, show rates of hearing loss among 28 patients who took teprotumumab were higher than previously reported in phase 2 and 3 trials.
Comparing Treatment Outcomes in Eyes With Proliferative Diabetic Retinopathy and NVE, NVD
Disc neovascularization (NVD) was less frequent among patients with proliferative diabetic retinopathy but was associated with more resistance to currently available treatments compared with neovascularization elsewhere (NVE), according to post hoc analysis findings published in JAMA Ophthalmology.
Fear of COVID-19 Limits Patients’ Uptake of Ophthalmic Care
Fear of exposure to COVID-19 is associated with patients missing ophthalmic care appointments, suggesting the potential importance of conveying practices’ infection-control measures, according to results of a non-validated survey.
Macular Damage May Lead to Impaired Facial Recognition
Field loss may not be the only visual deficit resulting from macular damage while resulting functional losses may impair facial recognition, according to new research published in JAMA Ophthalmology.
Program Aims to Increase Genetic Testing for Inherited Retinal Degenerations
Implementation of the free My Retina Tracker Genetic Testing Study program was associated with an increased proportion of patients with inherited retinal degeneration successfully obtaining genetic testing, according to analysis results published in JAMA Ophthalmology.
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