The AJMC® Ophthalmology compendium is a comprehensive resource for clinical news and expert insights for treatment of disorders of the eye.
Visual Field Defects Are Consistent in Macular Measurements Among Those With Glaucoma, High Myopia
Findings published in BMC Ophthalmology suggest that during diagnosis and follow-up of glaucoma with high myopia, more attention ought to be focused on structure and functional defects in macular areas.
Female Hormone Therapy Not Associated With Increased Risk of Retinal Vein, Artery Occlusions
Women filling a prescription for female hormone therapy (FHT), and presumably taking FHT, are not at increased risk of retinal artery or retinal vein occlusions.
Meta-analysis Outlines Accuracy of Red Reflex Test
An abnormal red reflex finding most likely reflects an underlying ocular pathology in infants, but finding a normal red reflex during screening does not altogether exclude ocular disease.
Rise in Drug Use–Related Hospitalizations for Endogenous Endophthalmitis
Between 2003 and 2016, the United States saw a 4-fold increase in drug use–related endogenous endophthalmitis hospitalizations, contributing to a substantial health care use burden.
Research Highlights Efficacy of Teprotumumab for Thyroid Eye Disease
New data to be presented at the American Academy of Ophthalmology’s Annual Meeting highlight the efficacy of Tepezza (teprotumumab), the first and only FDA approved medicine for thyroid eye disease.
Diabetic Retinopathy Severity Associated With Central Retinal Vessel Density in Eyes Without PPL
Central retinal vessel density is associated with diabetic retinopathy severity in eyes without, but not with, predominantly peripheral lesions (PPL) according to a study published in JAMA Ophthalmology.
Vision Impairment Associated With Lower Preventive Screening Service Rates in Older Adults
Older Americans with vision impairment may be less likely to use cancer-related preventive services compared with their counterparts without vision impairment.
Vitamin D, Marine ω-3 Fatty Acid Supplementations Have No Impact on AMD
Results from a prespecified ancillary study show neither vitamin D3 nor marine ω-3 fatty acid supplementation had a significant overall effect on age-related macular degeneration (AMD) incidence or progression.
Study Outlines Genetic, Ophthalmologic Characteristics of Rare Retinitis Pigmentosa Subtype
In a longitudinal cohort study, researchers identified 17 seemingly novel variants of the PDE6A retinitis pigmentosa gene, suggesting it may be amenable to gene therapy.
Researchers Estimate Lifetime Outcomes of Anti-VEGF Treatment for nAMD
Anti–vascular endothelial growth factor (VEGF) treatment was associated with preserved useful visual acuity in almost 20% of patients with neovascular age-related macular degeneration (nAMD).
Age Impacts Success of Probing for Congenital Nasolacrimal Duct Obstruction
Although probing for congenital nasolacrimal duct obstruction is safe and effective , age at the time of initial intervention and bilateral surgery constitutes a significant risk for a failed procedure, according to study results published in BMC Ophthalmology.
Researchers Use OCT-A to Determine Association Between Ocular Features, ACS
Acute coronary syndrome (ACS) was associated with lower inner vessel length density, measured via optical coherence tomography angiography (OCT-A), and with higher concentrations of angiopoietin-2 and osteoprotegerin, according to study results published in Scientific Reports.
Trial Finds Low-Dose Atropine Eyedrops May Slow Myopia Progression
Compared with placebo, low-dose atropine (0.01%) eyedrops may slow myopia (nearsightedness) progression and axial elongation in Chinese children with low and moderate myopia.
Report Describes Case of SARS-CoV-2 Found in Ocular Tissues of Former COVID-19 Patient
Researchers found the nucleocapsid protein (NP) antigen of SARS-CoV-2, the virus which causes coronavirus disease 2019 (COVID-19), existed intracellularly in the ocular tissues of a patient who previously had COVID-19.
Data Highlight Efficacy, Safety of Potential Pharmacologic Treatment for Ptosis
Oxymetazoline, 0.1% may hold potential as a promising treatment option for individuals with acquired blepharoptosis, according to results of a pooled analysis published in JAMA Ophthalmology.
Membrane Contraction Contributes to Increase in Choroidal Thickness in Patients With ERM
In patients with idiopathic epiretinal membrane (ERM), membrane contraction contributed to increased choroidal thickness, according to study results published in PLoS One.
Ban on Gay Men Donating Corneas May No Longer Be Supported by Evidence
Federal policy in the United States and Canada prohibiting men who have sex with another man (MSM) from donating corneas has led to the disqualification of between 1558 and 3217 cornea donations in 2018 alone, according to research published in JAMA Ophthalmology.
Tool Holds Potential for Biomarker-Based Diagnoses of Adolescent Concussion
For the first time, researchers demonstrated that quantitative pupillary light reflex (PLR) metrics can be used to differentiate concussed adolescent athletes from healthy athletes.
Age of Myopia Onset May Impact Risk of High Myopia in Adulthood
The risk of developing high myopia is relatively high among children with myopia onset at a young age, while each year of delay in the age of onset substantially reduces the chance of developing high myopia in adulthood.
Can Wearing Eyeglasses Mitigate COVID-19 Risk?
Among individuals hospitalized with coronavirus disease 2019 (COVID-19) in Suizhou, China, the proportion of patients who wore glasses for extended daily periods was smaller than the general population.
High Add Power Multifocal Contact Lenses Slow Myopia Progression in Children
In children, high add power multifocal contact lenses significantly reduced the rate of myopia (nearsightedness) progression over 3 years compared with medium add power and single-vision lenses.
Study Details Long-term CSC Recurrence After IVBI Treatment
In patients with central serous chorioretinopathy, eyes treated with intravitreal bevacizumab injections and which achieved complete resolution of subretinal fluid have a 50% chance of CSC recurrence in the long term.
Model Finds AI Diagnosis of Pediatric Diabetic Retinopathy Effective, Cost-Saving
Point-of-care diabetic retinopathy screening using autonomous artificial intelligence (AI) systems is effective and cost-saving for children with diabetes and their caregivers.
Pandemic May Significantly Limit Access to Pediatric Ophthalmology Care
Survey results show the coronavirus disease 2019 pandemic will leave some pediatric ophthalmology practices strained if not irreparably harmed.
Researchers Repair Damaged Corneas Using Healthy Stem Cells
For the first time in the United States, researchers have rebuilt damaged corneas using a patient’s own stem cells to aid in the recovery from ocular injuries such as chemical burns.
Study Highlights COVID-19 Ocular Manifestations in Children
Children hospitalized with coronavirus disease 2019 (COVID-19) in Wuhan, China presented with a series of eye manifestations, according to a new study.
Study Highlights Sex Differences in Stargardt Disease
Sex may play a modifying role in the 25% of patients with Stargardt disease who carried a combination of a mild and a severe allele, according to results of a cross-sectional study published in JAMA Ophthalmology.
Review Highlights Role of OCT-A in Neurodegenerative Diseases
According to a review published in Eye and Brain, the use of OCT-A, a noninvasive imaging technique for analyzing the retinal and choroidal microvasculature in vivo, can play a pivotal role in the detection and monitoring of neurodegenerative diseases.
Are Ophthalmology Practices Adhering to AAO Guidelines?
A study published in JAMA Ophthalmology found that as of April 30, 2020, most practices were complying with American Academy of Ophthalmology (AAO) guidelines for scheduling patients during the pandemic.
Does Retinal Microvascular Structure Impact Neurocognitive Development in Children?
Retinal venular widening and a higher vessel tortuosity are associated with lower performance of short-term visual recognition memory in children aged 4 to 5 years, according to a study published in JAMA Network Open.
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