An estimated 1 in 4 patients treated with durvalumab and chemotherapy (gemcitabine plus cisplatin) was alive at 2 years compared with 1 in 10 treated with chemotherapy alone, with these results contributing to the FDA's approval of the first immunotherapy to treat these cancers.
The case emphasizes the importance for clinician awareness of the potential for rare immune-mediated disorders, including acquired hemophilia A (AHA), following allogeneic hematopoietic stem cell transplantation (HSCT).
A new therapeutic paradigm has heightened the need for meaningful measures of assessing patients.
CVS announces its plan to buy Signify Health for $8 billion; government budgets and low reimbursement could limit the ability for new moms to stay on Medicaid for a year after childbirth; the long-lasting symptoms of COVID-19 could be keeping millions of people out of the workforce.
A new study finds anxiety and depression are more common in people with systemic lupus erythematosus (SLE) if they also have nephritis.
The increase in the incidence of hepatocellular carcinoma in Louisiana was nearly double that of the United States as a whole between 2005 and 2015.
The management of myeloproliferative neoplasms (MPNs) in adolescent and young adult (AYA) patients is currently similar to that of older patients. However, comprehensive research is needed to form guidelines for this younger population.
The multidisciplinary home care program aims to improve health outcomes and functioning while reducing health care use and preventing long-term nursing home placement.
A review of 6 studies on treatment options for hepatic encephalopathy found that many require further research before they can be recommended.
Inactive occupational status and low educational level were associated with pain, late disease onset, and greater number of affected areas in patients with hidradenitis suppurativa.
A digital pet app used as a prescription digital therapeutic (PDT) to encourage children to complete prescribed therapies received high engagement and function scores from children living with neurodevelopmental disabilities.
The ALLIANCE trial is investigating the responses of treatment-naïve persons living with comorbid HIV (PLWH)/hepatitis B virus to a triplet regimen of bictegravir/emtricitabine/tenofovir alafenamide vs dolutegravir plus emtricitabine/tenofovir disoproxil fumarate.
A recent review suggests point-of-care ultrasound can help home hospital care providers assess, diagnose, and monitor a range of conditions with relatively little additional training.
Older adults who reported longer total sleep time, lower rapid eye movement (REM) sleep percentage, and higher minimum oxygen saturations during REM sleep had an increased risk of developing Parkinson disease (PD).
Machine learning models collected using a crowdsourcing approach that provide feasible, quick, and accurate methods to quantify joint damage in rheumatoid arthritis (RA) could potentially be incorporated into electronic health records.
The researchers compiled data from studies of lirentelimab, mepolizumab, reslizumab, and benralizumab, highlighting the difficulties in finding an effective approach with eosinophil-targeted treatments for eosinophilic esophagitis (EoE).
Groups at risk for underrecognition and undertreatment of depression had improved rates of depression screening after implementing routine adult depressions screening in primary care.
The review of 5 phase 3 randomized controlled trials found that overall, the combination treatments improved survival outcomes while eliciting more, but manageable, side effects.
A narrative review found that some risk factors may be associated with cognitive impairment in patients with type 1 diabetes.
As the feasibility of phase 1 clinical trials for prenatal spinal muscular atrophy (SMA) therapies is explored, patient and parent input on prenatal testing and possibly treatment is a valuable tool for guiding research discussions.
Nurse-led education is an essential aspect of care for patients with bleeding disorders, but there is currently a lack of research on specific strategies to improve patient self-management through education.
A new analysis found only 1 in 10 studies of inequities in liver cancer had a European focus or origin.
New studies have linked a diet of ultra-processed food to a higher risk of colorectal cancer and to an overall risk of mortality; the CDC endorsed the updated booster shots from Moderna and Pfizer-BioNTech for use against the omicron variant; South Carolina Department of Corrections and Pear Therapeutics are teaming up to support inmates recovering from substance use disorders.
Coverage of our peer-reviewed research and news reporting in the health care and mainstream press.
While there are a number of treatment options available for patients with chronic obstructive pulmonary disease, not all options are right for all patients.
While there are a number of treatment options available for patients with chronic obstructive pulmonary disease, not all options are right for all patients.
David E. Koren, PharmD, MPH, BCPS, AAHIVP, FIDSA, infectious disease clinical pharmacist at Temple University Hospital, speaks on gaps in monkeypox vaccine availability and access and steps to improve response to the public health emergency.
A high-dose influenza vaccine reduces the risk of death and incidence of hospitalization for influenza and pneumonia among older adults.
This open-label extension of the SERAPHIN trial evaluated the long-term safety and tolerability of a small daily dose of the endothelin receptor antagonist against pulmonary arterial hypertension (PAH) among patients from the original study.
Medication-at-home pharmacy is an innovative method of medication management that is vital to the success of the health care system.
