Researchers conducting a large epigenome-wide association study identified several methylation sites associated with hereditary transthyretin amyloidosis (hATTR), a rare, life-threatening disorder caused by amyloidogenic coding mutations in the TTR gene.
This week, the top managed care news included FDA advising against changes to vaccine dose schedules; drop in mammography screenings during the first months of the pandemic; first anti-TIGIT therapy granted Breakthrough Therapy designation by the FDA.
Patients with psoriasis may be more likely to have additional autoimmune disorders, including vitiligo, diabetes, autoimmune thyroiditis, rheumatoid arthritis, and inflammatory bowel disease.
Patients with heart failure should be prioritized during vaccine rollout because of increased mortality risks reportedly associated with coronavirus disease 2019 (COVID-19).
A recent meta-analysis appearing in Journal of Cancer indicates a connection between minimal residual disease (MRD)–positive status and worse progression-free survival (PFS) and overall survival (OS) following induction and consolidation therapies.
Complete response to first-line therapy, as determined by the International Working Group 2006 response criteria, can be used as a surrogate end point for overall survival in higher-risk patients with myelodysplastic syndromes (MDS), according to a study published in Cancer Medicine.
A Democratic majority in the United States Senate could mean changes in health care policy are to come; CDC says benefits of the coronavirus disease 2019 (COVID-19) vaccine outweigh risks of allergic reactions; Los Angeles faces a shortage of oxygen.
Michael Snyder, PhD, professor and chair of genetics at the Stanford University School of Medicine, discusses the ways in which precision health measurements can aid physicians in detecting and better managing diabetes.
Age, renal disease, and suboptimal myeloma control were among the many factors identified in a recent study as increasing the risk of death from coronavirus disease 2019 (COVID-19) for patients being treated for multiple myeloma (MM).
Telehealth services have saw a spike in October as COVID-19 cases continued to rise, as seen in claims tracked by FAIR Health.
Study findings, published in Frontiers in Medicine, underscore the importance of metabolic profiling for discovering candidate screening biomarkers for interstitial lung disease (ILD) in rheumatoid arthritis.
Addressing the social health needs of those ill with coronavirus disease 2019 (COVID-19) is a challenge for providers and health care systems. On this episode of Managed Care Cast, we speak with Bechara Choucair, MD, senior vice president and chief health officer for Kaiser Permanente, who discusses the organization's guide that walks clinicians through considerations to keep in mind when screening patients in order to improve health outcomes as well as reduce community transmission.
The coronavirus disease 2019 (COVID-19) pandemic disrupted many mental health services for children; a study on the long-term effects of COVID-19 will soon kick off; a $13-billion deal has been struck for UnitedHealth to buy Change Healthcare.
Pain is a subjective response with multiple features and components, said Frank Porreca, PhD, professor of pharmacology and anesthesiology at the University of Arizona and a member of the Department of Collaborative Research at Mayo Clinic in Arizona.
Despite limited resources to combat the coronavirus disease 2019 pandemic, collaborative efforts among the government, health plans, and providers in Puerto Rico exemplify how care can be better optimized in communities in the United States impacted by disparities in health care services.
Decades ago, companies refused to heat-treat their blood products, which resulted in pooled plasma, among others, enabling many viruses to be transmitted, noted Robert K. Massie Jr, PhD, MA, of the Society for Progress.
In recent clinical practice guidelines issued by the American Academy of Sleep Medicine (AASM), authors established recommendations for the use of behavioral and psychological treatments for chronic insomnia disorder in adults.
In an effort to detect sea fan neovascularization from ultra-widefield color fundus photographs from patients with sickle cell hemoglobinopathy, researchers developed an automated system with high sensitivity and specificity, which holds potential to improve screening for vision-threatening proliferative sickle cell retinopathy.
The FDA warns against making any changes to the authorized dosing schedules of coronavirus disease 2019 (COVID-19) vaccines; joint health care venture, Haven, dissolves; Moderna announced it will increase production of its vaccine by 100 million doses for 2021.
The emotional, functional and physical effects of vertigo on patients with vestibular migraine were shown to be more significant compared with the experiences of patients with benign paroxysmal positional vertigo (BPPV) in a recent study.
An abstract from last month’s San Antonio Breast Cancer Symposium identifies factors linked with longer-term controlled substance use after treatment of breast cancer with mastectomy plus breast reconstruction in women receiving opioids, benzodiazepines, and other sedative/hypnotics.
Patients with newly diagnosed Parkinson disease (PD) who carried mutations in the Parkin gene were found to exhibit worse quality of life, longer disease duration, and an earlier age at disease onset than those with PD who did not carry the mutation.
Results from a cross-sectional study show individuals with Parkinson disease exhibited decreased retinal vessel and perfusion density, as well as choroidal structural changes compared with age- and sex-matched controls.
A reduction in glycated hemoglobin (A1C) may result in improved perinatal and maternal outcomes among women with prepregnancy diabetes, according to results of a cohort study published in JAMA Network Open.
Discussions between the FDA and Operation Warp Speed officials have mentioned the implementation of half-dose coronavirus disease 2019 vaccine regimens; the United Kingdom becomes the first country to administer the AstraZeneca/Oxford vaccine; the outlook for mental health in 2021.
A new study from Sweden cautions against routine discontinuation of renin-angiotensin system (RAS) inhibitors in patients with chronic kidney disease (CKD).
Chimeric antigen receptor (CAR) T-cell exhaustion likely stems from chemotherapy prior to transplant, noted Michael R. Green, PhD, University of Texas MD Anderson Cancer Center.
Coronavirus disease 2019 (COVID-19) dominated 2020. This is a look back at how the pandemic evolved and progressed through the year, which closed with the arrival of vaccines, but also continued challenges.
