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Sacubitril/valsartan reduced mean pulmonary artery pressure (mPAP) and improved lung congestion, functional capacity, and quality of life in a subset of patients with heart failure with preserved ejection fraction and pulmonary hypertension (HFpEF-PH) using a remote monitoring platform.

Investigators in Spain tested whether the tool would work in elderly patients in the primary care setting.

The label expansion means risdiplam is approved for spinal muscular atrophy for all ages.

The researchers found that socioeconomic status likely drives survival disparities between Hispanic patients and non-Hispanic whites (NHWs). They also found that, while both underserved populations, Hispanics and non-Hispanic blacks have different survival outcomes compared with NHWs.

Patients with comorbid chronic rhinosinusitis (CRS) with nasal polyps and asthma reported significant reductions in endoscopic sinus score and severity, as well as decreased dosage of oral steroids and antibiotics after long-term use of budesonide nasal irrigation.

The year that full benefits will stop for Medicare and Social Security is now a year later than previously estimated; diagnostic companies are racing to develop tests for monkeypox as cases surge; the rate of firearm suicides increased by 15% in youth aged between ages 10 and 24.

A retrospective study found low treatment adherence and no significant benefits to adjuvant chemotherapy or chemoradiotherapy following cholangiocarcinoma resection.

A recent review found that patients with chronic obstructive pulmonary disease (COPD) were at increased risk for mild cognitive impairment and dementia.

Coverage of our peer-reviewed research and news reporting in the health care and mainstream press.

Age-related macular degeneration (AMD) was found to be associated with relative telomere length in women specifically when investigating older patients.

Drawing on data from more than 2000 patients, the researchers of the retrospective study found that pulmonary function test results were associated with overall survival in non-small cell lung cancer (NSCLC).

Prior to the pandemic, youth with sickle cell disease were more likely to report depressive symptoms, but the opposite was true during the pandemic.

Findings from the phase 3 SHINE trial could make ibrutinib the standard treatment option for older patients with mantle cell lymphoma (MCL), who often cannot tolerate chemotherapy or transplant strategies, according to study authors.

Chest computed tomography scans demonstrated a lower frequency of pneumonia in fully vaccinated patients compared with unvaccinated patients, with a significantly lower frequency among patients who received the Pfizer vaccine.

Researchers published a framework and course design of digital brief therapy for insomnia (dBTI).

The drop in telehealth utilization was likely due to continuing reduction in the reported number and severity of COVID-19 infections, which may have led more patients to return to in-person healthcare services.

Prescribing is a complex process with multiple factors to consider on top of the 3 primary questions about effectiveness, harm, and cost. Pharmacogenetics has put this complexity under the spotlight and prompted educational programs and the development of new clinical decision support systems.

Whole-exome sequencing of a family with early-onset cancers found a novel variant in programmed cell death 1 ligand 2 that could potentially indicate germline predisposition to lymphoma.

The FDA approval for Fylnetra represents the fifth approval for a biosimilar referencing Neulasta (pegfilgrastim) in the United States.

Risk of ectopic pregnancy, the leading cause of maternal morbidity and mortality in the first trimester of pregnancy, was significantly associated with psoriasis in Danish women, especially those with moderate to severe disease.

For the second year, the meeting will focus on health equity, as American Society of Clinical Oncology (ASCO) President Everett Vokes, MD, FASCO, has selected the theme “Advancing Equitable Cancer Care Through Innovation.”

Regeneron will purchase Sanofi’s stake of cemiplimab (Libtayo) for $900 million in addition to royalties and other possible payments; a patient receives a 3D printed ear implant created using her own cells; the FDA accepts Pfizer’s EUA application for its COVID-19 vaccine for children aged younger than 5.

A cure for sickle cell disease could more than double the lifetime incomes of patients, the study found.

Randall A. Oyer, MD, medical director, oncology, and medical director, Cancer Risk Evaluation Program, Lancaster General Health, and clinical professor of cancer biology at Penn Medicine, discusses the recent American Society of Clinical Oncology/Association of Community Cancer Centers recommendations for improving diversity in clinical trials.

Forty-two percent of patients in the cohort had an adverse pregnancy outcome.

Kashyap Patel, MD, CEO of Carolina Blood and Cancer Care Associates, current president of the Community Oncology Alliance, and associate editor of Evidence-Based Oncology™, talks with us ahead of the 2022 American Society of Clinical Oncology (ASCO) Annual Meeting.

Susan Redline, MD, MPH, professor of sleep medicine and epidemiology, Harvard T.H. Chan School of Public Health, gives a preview of her SLEEP 2022 keynote and discusses her 30 years of sleep epidemiology advocacy.

Encouraging outcomes in recent studies have the authors of a recent review calling for more research on the effect of cannabinoids on sleep disorders.