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Using next-generation sequencing (NGS) in clinical workflows may help address disparities in uterine cancer, which has a higher mortality for Black women.

Due to the lack of head-to-head trials comparing chemoimmunotherapy regimens with chemotherapy alone as first-line treatment for non-small cell lung cancer, researchers conducted a network meta-analysis of 17 randomized controlled trials of patients with the cancer.

Major polypharmacy use was found to increase risk of mortality between 22% and 135% for American adults with chronic kidney disease (CKD) in this subanalysis of data from the REGARDS study.

An uptick in modeling and genomic data caused by the COVID-19 pandemic could lead to important infection-prevention measures in health care settings.

Using a systems biology approach, the researchers discovered 64 genes shared between non-alcoholic fatty liver disease (NAFLD) and hypertension, considered to be core genes for the 2 conditions.

Late July brings a 64% enrollment increase; owner charged with fraudulently billing Medicare over $784 million; COVID-19 hot spots lose nurses due to burnout.

Researchers compared billing codes from electronic health records to accurately quantify how many skin cancers patients had.

Fear of negative emotions, lack of interest, and distrust of medical institutions were some of the reasons that participants refused to receive information regarding medically actionable secondary genetic findings, even after they received additional education on what the findings would include.

Investigators conducted a questionnaire-based study among patients who suffered pediatric migraine or tension-type headache.

In a recently published review, authors assessed the relationship between poor bone health and type 1 diabetes (T1D) and outlined potential mechanisms that may account for the association.

Vizient recently released its Summer 2021 Pharmacy Market Outlook, which projects pharmaceutical spending for 2022 based on an analysis of its members' data. On this episode of Managed Care Cast, we talk about some of the findings.

Chemotherapy is standard care for pediatric acute lymphoblastic leukemia (ALL), but new research shows thiopurines can cause mutations that result in relapse.

Findings of the Adult Changes in Thought study present a significant link between long-term air pollution exposure and increased risk of dementia.

A new prospective cohort study suggests joint pain, rather than skin pain or disease severity, correlates with greater use of analgesics.

Department of Defense details plan on a COVID-19 vaccine mandate for all active-duty personnel; United Nations climate change report addresses likelihood of future extreme weather events tied to global warming; Government Accountability Office report finds greater readmission risk in understaffed skilled nursing facilities.

Bobeck Modjtahedi, MD, elaborates on the importance of devising effective and convenient mechanisms for diabetic retinopathy screening.

Dawn Averitt opened the session, “Refocus on HIV: How Innovation in HIV Will Address Individual Patient Needs,” on day 1 of IAS 2021, this year's virtual annual meeting of the International AIDS Society, which took place July 18-21.

We can safely delay excising in situ and early-stage melanomas while managing our patients’ care, noted Todd Schlesinger, MD, FAAD, director, Dermatology and Laser Center of Charleston and Clinical Research Center of the Carolinas.

Multidisciplinary care is an ideal way to management non-alcoholic fatty liver disease (NAFLD) because it is a complex disease associated with numerous comorbidities and necessitating lifestyle changes.

New research published in JAMA Network Open highlights one potential cause of migraine.

Camillo Ricordi, MD, FNAI, outlines the current status of islet transplantation for patients with type 1 diabetes in the United States.

Anthony Fauci, MD, addresses potential vaccine mandates once COVID-19 vaccines gain full approval; the FDA issues finalized guidance on using a metastasis-free survival end point in clinical trials of patients with prostate cancer; spotlighting the threat of variant spread and mutation amid case surges nationwide.

The new report compared the benefits of sodium-glucose co-transporter 2 (SGLT2) inhibitors with those of other glucose-lowering drugs and found lower rates of heart disease and mortality.

Clostridioides difficile, a bacteria that creates inflammation of the colon and causes symptoms like infectious diarrhea, is of particular risk among hospitalized patients.

Getting vaccinated is important to protect yourself, your family, and your community, says William "Andy" Nish, MD, an allergist and immunologist at Northeast Georgia Physicians Group.

FDA approves avalglucosidase alfa-ngpt (Nexviazyme) for the treatment of patients 1 year and older with late-onset Pompe disease.

The analysis included 64 cost-effectiveness analysis scenarios across more than 30 studies between 2009 and 2019, approximately half (53%) of which determined precision diagnostic testing to be cost-effective.

Relaxed social and professional constraints brought on by pandemic-related lockdowns benefitted the sleep schedules of patients with central hypersomnias.