All News

A new meta-analysis finds high rates of efficacy and high rates of toxicity in multiple myeloma patients treated with B-cell maturation agent (BCMA)-targeted chimeric antigen receptor (CAR)- T cells.

The panel could not reach consensus on what an expanded label might look like in an area where there are no approved therapies.

An outcomes-based agreement conducted by Boehringer Ingelheim and Highmark found that use of Jardiance (empagliflozin) among adults with type 2 diabetes (T2D) and known cardiovascular disease (CVD) was associated with a total cost of care savings of over 20%.

Visual hallucinations (VH) among patients with Parkinson disease (PD) appear to be associated with thinning of the inner retina, according to research published in Scientific Reports.

In a recently published review, researchers highlighted the disease burden of migraine, advances in preventive therapies, key takeaways from the most recent migraine management consensus statement, and advocated for increased pharmacist intervention in migraine medication management.

Kashyap Patel, MD, associate editor of Evidence-Based Oncology, a publication of The American Journal of Managed Care, will serve a 1-year term beginning in January.

FDA regulators find Moderna's experimental coronavirus disease 2019 (COVID-19) vaccine safe and effective; 27 states and the District of Columbia are asking HHS to step in regarding drug companies restricting access to 340B pharmaceuticals; pandemic worsens food insecurity in America.

In an abstract presented at CHEST 2020, investigators revealed that the emotions that patients with pulmonary arterial hypertension (PAH) regarding their illness are more complex than previously thought.

Friction of surgical instruments has the greatest association with incisional Descemet membrane detachment (DMD) during cataract surgery, according to results of a case series published in JAMA Ophthalmology.

Results from a phase 2 trial show PXL770 yielded consistently greater responses in high-risk patients with comorbid nonalcoholic steatohepatitis (NASH) and type 2 diabetes (T2D) compared with placebo.

Stark realities exposed by the pandemic have led some to advocate for redirecting resources to have the most impact on vulnerable populations.

Answer our poll: What do you think was the top non–COVID-19 story in 2020?

AstraZeneca has agreed to acquire Alexion Pharmaceuticals for $39 billion; CDC issues coronavirus disease 2019 (COVID-19) vaccine guidance for those with a history of severe reactions to vaccines; 2.9 million COVID-19 vaccine doses began traveling this past weekend to all 50 states.

The analysis, published in Cephalalgia, found that more than 50% of patients exhibited reversion from chronic migraine to episodic migraine after week 12 of the double-blind treatment phase.

Insurance status can influence an individual’s ability to access care, stated Milena Murray, PharmD, MSc, BCIDP, AAHIVP, associate professor at Midwestern University College of Pharmacy.

The authors wrote that in states that expanded Medicaid health insurance coverage in 2014, there was an increase of early-stage colon cancer diagnoses compared with states that did not implement expansion.

Scientists in Japan describe how a population of spinal cord astrocytes appear to have a role in producing pain hypersensitivity.

Patients with COVID-19 and end-stage renal disease were 11 times more likely to be admitted to the hospital than patients without kidney disease.

The findings help explain why costly CAR T-cell therapy does not work for some patients.

Circulating tumor DNA (ctDNA) has a host of benefits in treating and managing patients with early-stage disease, noted Alexey Aleshin, MD, senior medical director of Oncology at biotech giant Natera.

A review published earlier this year examines the rationale and evidence for using a multidrug approach in pulmonary arterial hypertension (PAH).

The study showed that that patients with higher disease activity had significantly lower levels of physical activity.

A variety of factors contributed to discontinuation rates in FIDELIO-DKD, said George Bakris, MD, professor of medicine and director of the American Heart Association Comprehensive Hypertension Center at the University of Chicago Medicine.

The genes are part of the family that cause cancer cells to grow.

The abstract, presented at the 2020 American Society of Hematology Annual Meeting and Exposition, found favorable overall survival and leukemia-free survival for these patients.

In its 2021 Hospital Outpatient Prospective Payment Final Rule, CMS announced it will delay its radiation oncology payment model from January 2020 until July 2021.

Among patients with obstructive sleep apnea (OSA), the presence of anxiety was shown to have an inverse relationship with the severity of OSA, whereas symptoms of depression did not exhibit a similar relationship.

Despite heavy alcohol consumption being linked to increased incidence of atrial fibrillation (AF) and bleeding in patients with the condition, recommendations to control heavy drinking among this patient population are lacking.