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New study findings have identified a subtype of multiple sclerosis—myelocortical multiple sclerosis—that has neuronal loss but no demyelination of the brain’s white matter, indicating that demyelination and neuronal degeneration occur independently.

The public, including most Republicans, wants protections for people with pre-existing conditions preserved, finds the latest Kaiser Family Foundation health tracking poll. The poll was released as a federal court case regarding the constitutionality of the Affordable Care Act got underway in Texas and as Brett Kavanaugh began his second day of questioning from senators regarding his nomination to the Supreme Court.

While funders and researchers have long held that clinical trials should enroll more diverse patients to better reflect the populations in which approved drugs will eventually be used, patient populations enrolled in clinical trials remain largely homogenous.

In the second quarter of 2018, real US drug prices declined 5.8%, and it may be thanks to co-payment accumulators; more than 25 patient and consumer groups released a statement that said a new bill to protect Americans with pre-existing conditions would not be sufficient; the Department of Justice has issued a warning to cities planning to set up supervised injection sites as a tactic to curb opioid overdose deaths.

FDA's designation is based on phase 2 data presented earlier this year at the American Society of Clinical Oncology Annual Meeting.

Newly published findings indicate that physician burnout is associated with an increased risk of patient safety incidents, poorer quality of care, and reduced patient satisfaction.

Consolidation in California’s healthcare system has had a noticeable impact on measures of vertical integration and premiums for insurance bought through the exchanges established under the Affordable Care Act, according to a study published Tuesday in Health Affairs.

Amgen has submitted a supplemental New Drug Application to the FDA to expand the prescribing information of carfilzomib (Kyprolis) to include a once-weekly dosing option in combination with dexamethasone for patients with relapsed or refractory multiple myeloma.

The COMBI study, a prospective, open‐label, single‐arm phase 2 study ongoing in Denmark, is investigating the feasibility of treating patients with low- to intermediate-risk myelofibrosis or polycythemia vera with low-dose pegylated interferon alfa-2 in combination with ruxolitinib.

A new index released by Oxfam has ranked Washington, DC, along with the 50 US states based on their policies around minimum wages, health and safety, leave, etc—which could be used as a surrogate for the well-being of the labor force. Virginia ranked last and Washington, DC, led the list.

Oncology care model (OCM) practices are awaiting CMS' release of the first performance period one true-up and performance period two initial reconciliation results.

A new long-acting treatment for hemophilia A has been approved for previously treated patients, aged 12 years and older. Bayer’s Jivi was also approved for on-demand treatment and the perioperative management of bleeding in the same population.

As the healthcare system considers alternative payment models that reward high-value care delivery, programs that utilize lay health workers (LHW) may be valuable. A study in JAMA Oncology analyzed whether an LHW program can increase the documentation of patients’ care preferences.

Ovid Therapeutics Inc., a biopharmaceutical company, recently announced that the phase 2 STARS trial, which tested the efficacy of the investigational drug OV101, achieved its primary endpoint of safety and tolerability for treating Angelman syndrome.

Fragility fractures are a serious complication of type 1 and type 2 diabetes, but many clinicians who treat patients with diabetes are not aware of the increased risk of these fractures.

Early hospital readmissions for patients with asthma and chronic obstructive pulmonary disease (COPD) represent a major economic burden within the healthcare system and recent research found that comorbid chronic rhinitis is significantly associated with 30-day asthma and COPD related readmissions

A recent review of nearly 582,000 heart attack cases over the span of 19 years found that female patients had a significantly higher survival rate when treated by a female physician in the emergency department.

New research from the Employee Benefit Research Institute has found that although there was some erosion in health insurance offered by employers after the implementation of the Affordable Care Act, the percentage of private-sector employers offering health benefits increased in 2017 for the first time since 2008.

Here are the top 5 articles for the month of August.

Coverage of our peer-reviewed research and news reporting in the healthcare and mainstream press.

E-cigarette use in the United States is more prevalent in people who are younger, have comorbid conditions, or are former or current conventional cigarette smokers, according to results from a recent Behavioral Risk Factor Surveillance System national report.

Researchers evaluating the different methods used to predict the progression of multiple sclerosis (MS) found that human–machine hybrid predictions led to better prognoses than did machine learning algorithms or groups of humans alone.

This week, the top managed care stories included encouraging results from the Next Generation Accountable Care Organization model; concerns that CMS' new billing rules will hurt the sickest patients; a study confirms the value of daily aspirin for patients with diabetes.

A study recently found that an immunotherapy combination treatment of ipilimumab (Yervoy) and nivolumab (Opdivo) shrank melanoma that had spread to the brain in more than half of participants.

It’s been more than 100 days since President Trump and HHS Secretary Alex Azar announced the “American Patients First” drug pricing blueprint. Here are 5 actions the government has taken since its release.

A judge tossed a lawsuit brought by pharmaceutical companies to block a California law requiring advance notice of big price increases; the FDA is testing all angiotensin II receptor blockers (ARBs) over a discovered impurity that is linked to cancer; research in monkeys has suggested that an experimental painkiller is effective at easing pain without being addictive.

A survey of patients in the United Kingdom who were diagnosed with cancer found that patients with blood cancers were the least likely to say they completely understood what was wrong when the doctor explained it. They were also less likely to say that their treatment options were explained before treatment started compared with patients with other cancers.

Patient with chronic migraine were more likely to have aggression, anger, and hostility. Comorbid aggression may help to identify suicidality in migraine patients.