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The most-viewed eosinophilic esophagitis (EoE) content of the year covered new developments in treatment options for EoE, the prevalence of EoE in the allergic disease population, and the impact of EoE on a child’s well-being.

Jessica Allegretti, MD, MPH, medical director of the Crohn's and Colitis Center, Brigham and Women's Hospital, explained the mechanism of action for Rebyota, the first fecal transplant therapy approved by the FDA for the prevention of recurrent Clostridioides difficile infection (CDI) in individuals 18 years and older, following antibiotic treatment for recurrent CDI.

In heart failure this year, value-based care, left ventricular ejection fraction, and disease prevention were among the most popular topics discussed.

A research letter examined the clinical presentation, disease severity, associated comorbidities, and management of hidradenitis suppurativa in older adults aged 65 years or older.

A new study found that short sleep duration and high siesta ratio were associated with a higher risk of hypertension and elevated risk of cardiovascular diseases.

Incidence of Parkinson disease in North America was 50% higher than previous estimates of 60,000 diagnoses annually.

The top 5 most-read content in leukemia and lymphoma for 2022 addressed chimeric antigen receptor T-cell therapy, updates in recommended treatment, and President Joe Biden’s announcement on the return of the Cancer Moonshot.

Diagnoses of psoriatic arthritis, rheumatoid arthritis, axial spondyloarthritis, or undifferentiated inflammatory arthritis saw a dramatic decline during the early stages of the COVID-19 pandemic.

A pair of abstracts presented at this year’s 64th American Society of Hematology Annual Meeting and Exposition bear out the significant transfusion-free rate at 3 years following beti-cell administration and marked improvements in patient-reported outcomes, including the ability to work and be physically active.

Content published on AJMC.com focusing on automated insulin delivery devices over the past year highlighted utilization of these devices by age, compared different types of systems, looked at barriers to uptake, and examined equity issues standing in the way of access.

A new study has found that Mexican Americans and non-Hispanic Black Americans had low rates of glycemic control compared with non-Hispanic White Americans.

Among young adults, 2-year cancer survival increased more in states with expanded Medicaid coverage; some pharmacies implemented purchase limits to help combat children’s medicine supply shortages; an FDA advisory panel will meet next month to discuss the state of the COVID-19 pandemic.

The top biosimilars content of 2022 reviewed perceptions around switching to a trastuzumab biosimilar, drug costs, and the successful implementation of biosimilars in practice.

New study findings call into question the necessity of spirometry as a criterion for participation in palliative care research among patients with chronic obstructive pulmonary disease (COPD).

A retrospective study found roxadustat to be more effective in improving hemoglobin levels in patients who had with chronic kidney disease (CKD) compared with recombinant human erythropoietin.

Overall survival for patients with combined hepatocellular-cholangiocarcinoma is poor, but those who received adjuvant transarterial chemoembolization (TACE) after surgery had a prolonged recurrence-free survival (RFS).

This new study, which followed patients up to 6 months after functional endoscopic sinus surgery, evaluated results using objective and subjective measures.

Martin Levine, MD, MBA, chief medical officer at the PolyClinic at Optum Washington, describes why caregivers need more resources to adequately manage patients with Alzheimer disease and what clinics can do to ensure access to those resources.

Eli Lilly is experiencing a shortage of the diabetes drug tirzepatide (Mounjaro); a data breach has caused over 200,000 Medicare enrollees to receive new identification cards; a restructuring of the current model for developing and selling antibiotics could be a solution to shortages and drug-resistant germs.

Having lower levels of a personality traits know as personal reserve was linked with an increased probability of sustained remission (SR) in patients with major depressive disorder.

Although rare, stiff person syndrome spectrum disorders can significantly affect patient quality of life, and current knowledge gaps warrant further research.

While the combination improved multiple depression scores, patients receiving both therapies did have more adverse events than those in control groups, the meta-analysis found.

A recent meta-analysis found ASXL1 mutations to be independent risk factors for worse overall survival and transformation to acute myeloid leukemia in patients with myelodysplastic syndromes (MDS), as well as worse overall survival in acute myeloid leukemia (AML).

The US Preventive Services Task Force (USPSTF) announced its recommendation for HIV pre-exposure prophylaxis (PrEP).

The combination therapy of levodopa and benserazide was associated with a significantly reduced risk of lower urinary tract infections, particularly among women, when compared with another Parkinson disease combination therapy of levodopa and carbidopa.

Tom Robinson, vice president of global access at JDRF, talks about how the community and people living with type 1 diabetes (T1D) have contributed to the T1D Index, from development to publication and going forward.

M. Hossein Kazemi, MD, medical oncologist and hematologist, Astera Cancer Care, identifies key tools in de-escalating treatment for patients with multiple myeloma.