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On this episode of Managed Care Cast, we discuss senior health needs amid the pandemic and how Centerwell Senior Primary Care's holistic, team-based approach and value-based care delivery contributed to upticks in senior patient visits despite fears of COVID-19.

Moderna's COVID-19 vaccine was found to be safe and effective in children aged 6 to 11 years; the Biden administration seeks to increase the availability of cost-effective rapid at-home COVID-19 tests; President Joe Biden will impose new vaccine requirements for international air travelers and lift current travel restrictions.

Pregnant women with psoriasis were found to be at increased risk of experiencing preterm birth and Cesarean delivery, with patients undergoing anti-rheumatic treatment during their first pregnancy indicated to be at significantly greater risk.

A pan-cancer reference atlas provides a framework for an immune-based patient stratification that study authors expect to be predictive for patient prognosis and immunotherapy response at an elevated level after further studies.

Results of a retrospective study found no benefits among older patients whose diabetes medication was intensified following short hospital admissions.

In patients refractory to conventional therapy, the combination resulted in a 70% reduction in a key biomarker compared with placebo.

Posters presented at AMCP Nexus 2021 evaluated the health care resource utilization (HRU) and costs associated with the chimeric antigen receptor T-cell therapies tisagenlecleucel and axicabtagene ciloleucel.

Migraineurs tend to have more anxiety when it comes to dental procedures compared with those without migraine.

Education is needed for both patients and pharmacists to ensure appropriate understanding, investigators reported at the Academy of Managed Care Pharmacy (AMCP) Nexus 2021 meeting.

The first-of-its-kind port delivery system with ranibizumab serves as the first wet age-related macular degeneration (AMD) treatment in 15 years to provide an alternative to frequent eye injections.

Local anesthesia yields superior outcomes in pregnant women with pulmonary arterial hypertension (PAH) undergoing cesarean deliveries compared with general anesthesia.

The nation's top infectious disease expert expects COVID-19 vaccination to be made available for children aged 5 to 11 years by early November; Walmart recalls aromatherapy spray due to rare and deadly bacteria contamination; COVID-19–related brain fog has been found to persist in patients for months after infection.

Patients and prescribers should be able to see the total bottom-line cost of medications along with the clinical support for why they are using them.

Many novel traits are shared through gene transfer, but scientists haven’t been able to determine why some bacteria engage in gene transfer while others do not.

An abnormal retention of mitochondria can trigger the cascade of inappropriate and harmful immune activity that is characteristic of lupus, the report said.

The issue of systemic lupus erythematosus (SLE) is particularly important in Asia, because patients there suffer from more severe disease and damage compared with patients in Western countries.

This new study from Serbia compared outcomes on oral glucose tolerance tests between women who are pregnant and those who have polycystic ovary syndrome (PCOS).

Two abstracts presented at the CHEST Annual Meeting 2021 showed that patients with narcolepsy treated with once-nightly sodium oxybate, FT218, vs placebo exhibited significant improvements in sleep latency and cataplexy.

The WISDOM study—Women Informed to Screen Depending On Measures of risk—was launched to test a personalized approach to screening compared to annual mammograms. Funmi Olopade, MD, FACP, is a professor of Medicine and Human Genetics and founding director of the Center for Clinical Cancer Genetics and Global Health at the University of Chicago Medical Center, and a co-investigator of WISDOM. She discussed how the COVID-19 pandemic actually helped increase participation in the WISDOM study and what it means for future trials.

Approximately half of patients with proliferative diabetic retinopathy exhibited long lapses in care when prescribed ranibizumab across a 5-year follow-up.

Molecular profiling is more often used after standard cancer treatments have failed; a recent study suggests that it could effectively guide first-line treatment, especially for cancers with a poor prognosis.

The MScanFit method assessed changes in motor unit configuration in adult patients undergoing treatment for spinal muscular atrophy (SMA).

A recent study found that nurses who worked in operating rooms for 15 or more years are 46% to 69% more likely to develop chronic obstructive pulmonary disease (COPD) than nurses who had never worked in an operating room.

Angelman syndrome affects roughly 1 in every 20,000 children and it has no approved treatment.

Researchers hope that the benefits seen in a new protocol for deep brain stimulation (DBS) in Parkinsonian mice will extend to humans.

A report suggests that people with chronic obstructive pulmonary disease (COPD) and asthma have a protein in their lungs that leaks a small molecule into their bloodstream that restricts their breathing instead of relaxing their airways.

Health care costs are 3 to 5 times greater for people with rare diseases compared with those without, according to a new study.

Mortality and liver-related complications increased with fibrosis stage in patients with nonalcoholic fatty liver disease (NAFLD).