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Test your knowledge of the April 2024 issue of AJMC with a quick quiz!

A case controlled study suggests a gene variant may offer some protection from frontal fibrosing alopecia (FFA), but only if there is no prior history of oral contraceptive pill use, which appears to increase the risk for carriers of this variant.

The treatment showed effectiveness in achieving local control of acute myeloid leukemia (AML) that developed in the eyes of a pediatric patient.

Shawn Kwatra, MD, dermatologist, John Hopkins University, recounts his study assessing the use of nemolizumab in prurigo nodularis presented at the American Academy of Dermatology conference.

The annual conference taking place from June 1 to June 5, 2024, will feature sessions on the relationship between mental health and sleep, artificial intelligence in sleep, and different sleep conditions.

This international study, incorporating data from the US, Brazil, Singapore, and Spain, shows that durvalumab as maintenance therapy for use against non–small cell lung cancer remains a cost-prohibitive treatment option.

A real-world study assessed the impact of cannabis-based medicinal products on health-related quality of life in patients with multiple sclerosis (MS).

Despite diversity enrollment goals, clinical trials funded by the National Institutes of Health (NIH) often enroll fewer patients among underrepresented racial groups; nicotine alternatives used in vapes may be more potent and addictive than nicotine itself; telehealth company Ro built a drug supply tracker to help patients find available doses of GLP-1 drugs.

In this episode of Managed Care Cast, Nihar Desai, MD, MPH, cardiologist and vice chief of Cardiology at the Yale School of Medicine, discusses therapies for cardiovascular conditions as they relate to patient adherence, polypharmacy, and health access.

A US study found that a commercially available artificial intelligence (AI) algorithm for breast cancer screening produced more false-positives in Black patients and people with denser breasts, highlighting the importance of diverse datasets in training AI algorithms to reduce health care disparities.

The report found a selective serotonin reuptake inhibitor (SSRI) did not offset the effects of myasthenia gravis (MG) medication.

In this interview ahead of the 2024 American Society of Clinical Oncology annual meeting (ASCO), Ravin Ratan, MD, MEd, The University of Texas MD Anderson Cancer Center, discusses study data he is excited to hear more about on the combination of trabectedin and low-dose irinotecan for relapsed/refractory Ewing sarcoma.

Findings from a retrospective study suggested a possible causal relationship between prior infection and the development of hypersomnolence disorders such as narcolepsy and idiopathic hypersomnia, but more research is needed.

A new report builds on previous research that could help scientists better understand type 1 diabetes (T1D) risk.

According to new research from Jordan, patients with both heart failure (HF) and diabetes had a higher prevalence of HF with preserved ejection fraction (HFpEF), elevated cholesterol, low-density lipoprotein, and impaired kidney function.

An analysis of 2 phase 3 trials supporting the use of pegcetacoplan (PEG) in the treatment of paroxysmal nocturnal hemoglobinuria (PNH) assessed the benefits of this treatment compared with eculizumab (ECU) and supportive care measures.

Scientists are worried that fertilized hen eggs remain the main ingredient for the H5N1 bird flu vaccine; an increased risk of preterm delivery and stillbirth exists in the US due to the worsening climate; health care executives are discussing whether they should bring in outside consultants or hire more employees in preparation for cyberattacks.

Clinical use of liquid biopsies to determine the likelihood of CRC is the goal based on its effectiveness in recent studies.

Recent studies reveal that simoctocog alfa (Nuwiq) offers effective prophylaxis and treatment for severe hemophilia A in children, with low inhibitor rates and strong long-term safety and efficacy.

A study using a large Korean health database found that people with a rare hair loss disorder called primary cicatricial alopecia were more likely to also have additional health problems like diabetes and high blood pressure compared with people who had other hair loss conditions or no hair loss at all.

Posters presented at the American Thoracic Society (ATS) 2024 International Conference examined factors of the pandemic that may have influenced the clinical presentation and diagnosis of respiratory symptoms, as well as health care resource utilization for serious asthma outcomes.

Exercise and dietary interventions reduced fatigue and improved both fat-free mass and physical functioning in patients with ovarian cancer (OC), but no significant differences in improvement were found between the intervention and control groups.

Amy Shapiro, MD, medical director, Indiana Hemophilia and Thrombosis Center, discusses the clinical trials that influenced plasminogen's (Ryplazim; Kedrion Biopharma) FDA approval, as well as details valuable information for the treatment of patients with plasminogen deficiency.

Expert speakers at the American Thoracic Society (ATS) 2024 international conference share their favorite parts of the event and the key takeaways they will leave the conference with.

Experts warn of insufficient support for patients amid surge in prescriptions for weight loss; new Florida law will allow C-sections in clinics; focus shifts to amending international health regulations for pandemic preparedness.

Among the many topics discussed at the American Thoracic Society 2024 International Conference (ATS 2024), the majority touched on barriers to health equity and access, regardless of the key focus of each talk or study. Experts examined this within the field, emphasizing the importance of enhancing data diversity, modernizing diagnostic tools, and revising regulatory standards to promote equitable health outcomes for diverse populations.

MicroRNAs could be a key to future testing for colorectal cancer (CRC) and determining treatment.

Cardiovascular disease (CVD) risk was reduced by 1.2% in the intention-to-treat analysis and 5% in the per protocol analysis for adults aged 75 and older.